Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mingxiong Tian"'
Autor:
Zhennan Zhao, Jingya Zhou, Mingxiong Tian, Min Huang, Sheng Liu, Yufeng Xie, Pu Han, Chongzhi Bai, Pengcheng Han, Anqi Zheng, Lutang Fu, Yuanzhu Gao, Qi Peng, Ying Li, Yan Chai, Zengyuan Zhang, Xin Zhao, Hao Song, Jianxun Qi, Qihui Wang, Peiyi Wang, George F. Gao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The SARS-CoV-2 Omicron variant spreads rapidly. Here the authors show that Omicron S preferentially adopts the one-RBD-up conformation, which leads to a non-RBM-binding monoclonal antibody escape. Mutagenesis reveals that S371L, S373P and S375F subst
Externí odkaz:
https://doaj.org/article/90e8f270726e4bf38984d7f2e5f9e902
Autor:
Chao Su, Juanhua He, Pengcheng Han, Bin Bai, Dedong Li, Jian Cao, Mingxiong Tian, Yu Hu, Anqi Zheng, Sheng Niu, Qian Chen, Xiaoyu Rong, Yanfang Zhang, Weiwei Li, Jianxun Qi, Xin Zhao, Mengsu Yang, Qihui Wang, George Fu Gao
Publikováno v:
Journal of virology. 96(17)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted between humans and minks, and some mutations in the spike (S) protein, especially in the receptor-binding domain (RBD), have been identified in mink-derived viruses. Here, we
Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2
Autor:
Pengcheng Han, Linjie Li, Sheng Liu, Qisheng Wang, Di Zhang, Zepeng Xu, Pu Han, Xiaomei Li, Qi Peng, Chao Su, Baihan Huang, Dedong Li, Rong Zhang, Mingxiong Tian, Lutang Fu, Yuanzhu Gao, Xin Zhao, Kefang Liu, Jianxun Qi, George F. Gao, Peiyi Wang
Publikováno v:
Cell
COVID-19 pandemic continues worldwide with many variants arising, especially those of variants of concern (VOCs). A recent VOC, Omicron (B.1.1.529), which obtains a large number of mutations in the receptor-binding domain (RBD) of the spike protein,