Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mingxia Zhai"'
Publikováno v:
Shipin Kexue, Vol 45, Iss 18, Pp 124-133 (2024)
This study was carried out in order to investigate the effects of goji berries fermented by Lactobacillus plantarum NXU0011 on serum metabolites in mice with ulcerative colitis (UC). A mouse model of UC was induced by oral administration of dextran s
Externí odkaz:
https://doaj.org/article/a145b1194b2449cab54e14cce07aae6f
Autor:
Yuanming Qi, Bingyu Li, Xinghua Sui, Wenjie Zhai, Mingxia Zhai, Jiangfeng Du, Guanyu Chen, Wanqiong Li, Xiaoxi Wang, Xueqin Zhu, Yahong Wu, Guodong Li, Xiuman Zhou, Yanfeng Gao
Publikováno v:
Journal of Controlled Release. 334:376-388
Blockade of the immune checkpoint PD-1/PD-L1 with monoclonal antibodies demonstrated unprecedented clinical efficacies in many cancers. But the orally available low molecular weight inhibitors remain infancy. Compared to small molecules, peptide exhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67f4f87d880a2de93bccd651b842803
https://doi.org/10.1016/j.jconrel.2021.04.036
https://doi.org/10.1016/j.jconrel.2021.04.036
Autor:
Yunhui Ran, Mingxia Zhai, Lingxiao Xing, Xiuman Zhou, Wenjie Zhai, Yanfeng Gao, Jiangfeng Du, Wenshan Zhao, Yuanming Qi, Yixuan Sun, Wanqiong Li
Publikováno v:
Science China. Life sciences. 64(4)
The interaction of PD-1/PD-L1 allows tumor cells to escape from immune surveillance. Clinical success of the antibody drugs has proven that blockade of PD-1/PD-L1 pathway is a promising strategy for cancer immunotherapy. Here, we developed a cyclic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daedbd25be9296e174d6b3ae6bd0bcdc
https://pubmed.ncbi.nlm.nih.gov/32737851
https://pubmed.ncbi.nlm.nih.gov/32737851
Publikováno v:
Cancer Immunology, Immunotherapy. 62:1723-1732
PIWIL2, a member of PIWI/AGO family, is expressed in germline stem cells and precancerous stem cells, but not in adult somatic cells. PIWIL2 plays an important role in tumor development. It is considered as a cancer–testis antigen (CT80). It has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a981b1d6c0204178c0b382ef5307d559
https://doi.org/10.1007/s00262-013-1478-7
https://doi.org/10.1007/s00262-013-1478-7
A Novel Cytotoxic T lymphocyte Epitope Analogue with Enhanced Activity Derived From Cyclooxygenase-2
Autor:
Ranran Shi, Y. J. He, Wenjie Zhai, Zongyin Wu, Mingxia Zhai, Yuanming Qi, Y. H. Wu, Yanfeng Gao, Meng Sun, X. Chen
Publikováno v:
Scandinavian Journal of Immunology. 76:278-285
Cyclooxygenase-2 is a promising target for cancer immunotherapy. Here, we designed the analogues p321-9L and p321-1Y9L (YLIGETIKL) from cyclooxygenase-2-derived native peptide p321. Then, we tested the binding affinity and stability of the analogues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa601ff4fe8e4b001bddb517d8fc16cc
https://doi.org/10.1111/j.1365-3083.2012.02738.x
https://doi.org/10.1111/j.1365-3083.2012.02738.x
Publikováno v:
Microbiology and Immunology. 56:548-553
The identification of novel cytotoxic T lymphocyte (CTL) epitopes is important to analysis of the involvement of CD8+ T cells in Mycobacterium tuberculosis infection as well as to the development of peptide vaccines. In this study, a novel CTL epitop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8dbad9a68802bc40f2855c8c82ca3ba
https://doi.org/10.1111/j.1348-0421.2012.00470.x
https://doi.org/10.1111/j.1348-0421.2012.00470.x
Publikováno v:
Scandinavian Journal of Immunology. 74:561-567
MAGE-4 is considered as an attractive cancer-testis (CT) antigen for tumour immunotherapy, and it is overexpressed in oesophageal carcinoma (EC). To identify MAGE-4-derived HLA-A2 restricted epitopes, native peptides and their analogues were predicte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d772857b399826569fb93525843ed23c
https://doi.org/10.1111/j.1365-3083.2011.02606.x
https://doi.org/10.1111/j.1365-3083.2011.02606.x
Publikováno v:
Immunology Letters. 140:68-73
Cytotoxic T lymphocytes (CTLs) play an important role in the immunity of Mycobacterium tuberculosis (Mtb) infection. In the present study, the identification of novel CTL epitopes from efflux pumps, Rv1258c and Rv1410c, was reported. Candidate native
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b643cecb702be8bbda63a605fd2cc39a
https://doi.org/10.1016/j.imlet.2011.06.009
https://doi.org/10.1016/j.imlet.2011.06.009
Autor:
Lu Li, Zongyin Wu, Yuanming Qi, Mingxia Zhai, Chao Dai, Yahong Wu, Yanfeng Gao, Wei Liu, Meng Sun
Publikováno v:
Amino Acids. 42:2257-2265
Identification of cytotoxic T lymphocyte (CTL) epitopes from tumor antigens is essential for the development of peptide vaccines against tumor immunotherapy. Among all the tumor antigens, the caner-testis (CT) antigens are the most widely studied and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3439902f54268726e7ce1f6feab49471
https://doi.org/10.1007/s00726-011-0966-3
https://doi.org/10.1007/s00726-011-0966-3
Autor:
Mingxia Zhai, Fei Chen, Yuhuang Zhu, Hong Lv, Yuanming Qi, Zongyin Wu, Lu Li, Yanfeng Gao, Yahong Wu, Wei Liu
Publikováno v:
Immunology Letters. 133:94-98
CFP21 is a major secreted protein of Mycobacterium tuberculosis (Mtb) which is considered as a promising antigen for immunotherapy. To identify CFP21-derived HLA-A*0201 restricted epitopes, a series of native peptides and their analogues were predict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1105d6af435de13aa910e75243f931da
https://doi.org/10.1016/j.imlet.2010.07.007
https://doi.org/10.1016/j.imlet.2010.07.007