Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mingxi Weng"'
Autor:
Mingxi Weng, Ralf Jauch
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 11, Pp 2333-2334 (2024)
Externí odkaz:
https://doaj.org/article/b27b5f6777674868b8e72f311781b919
Autor:
Vikas Malik, Laura V. Glaser, Dennis Zimmer, Sergiy Velychko, Mingxi Weng, Markus Holzner, Marius Arend, Yanpu Chen, Yogesh Srivastava, Veeramohan Veerapandian, Zahir Shah, Miguel A. Esteban, Huating Wang, Jiekai Chen, Hans R. Schöler, Andrew P. Hutchins, Sebastiaan H. Meijsing, Sebastian Pott, Ralf Jauch
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Oct4, along with Sox2 and Klf4 can induce pluripotency, but structurally similar factors like Oct6 cannot. Here, using pluripotency competent and incompetent factors, the authors show that Sox2 plays a dominant role in facilitating chromatin opening
Externí odkaz:
https://doaj.org/article/5d839fd6128d4d118a7cbf72a69b4f17
Autor:
Veeramohan Veerapandian, Jan Ole Ackermann, Yogesh Srivastava, Vikas Malik, Mingxi Weng, Xiaoxiao Yang, Ralf Jauch
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 593-606 (2018)
Summary: Directed biomolecular evolution is widely used to tailor and enhance enzymes, fluorescent proteins, and antibodies but has hitherto not been applied in the reprogramming of mammalian cells. Here, we describe a method termed directed evolutio
Externí odkaz:
https://doaj.org/article/4737b90551e640e2bf59e1c9bc496420
Autor:
Mingxi Weng1,2, Haoqing Hu1, Graus, Matthew S.3,4, Daisylyn Senna Tan1, Ya Gao1, Shimiao Ren1, Derek Hoi Hang Ho1,2, Langer, Jakob1, Holzner, Markus1, Yuhua Huang1, Guang Sheng Ling1, Cora Sau Wan Lai1,5, Francois, Mathias3,4,6, Jauch, Ralf1,2 ralf@hku.hk
Publikováno v:
Science Advances. 8/25/2023, Vol. 9 Issue 34, p1-23. 23p.
Autor:
Mingxi Weng, Sik Y. Ho, Xiaoxiao Yang, Yanpu Chen, Derek Hoi Hang Ho, Ralf Jauch, Jian Yan, Hans R. Schöler, Johannes Graumann, Gary D. Stormo, Yogesh Srivastava, Anastasia Bednarz, Ya Gao, Yuanjie Wei, Sergiy Velychko, Thomas Braun, Daisylyn Senna Tan, Johnny Kim, Vikas Malik, Ligang Fan
Publikováno v:
Molecular Biology and Evolution
Transcription factor-driven cell fate engineering in pluripotency induction, transdifferentiation, and forward reprogramming requires efficiency, speed, and maturity for widespread adoption and clinical translation. Here, we used Oct4, Sox2, Klf4, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a59703c3bb3cce02eb205c63ea6683d
https://doi.org/10.1093/molbev/msab075
https://doi.org/10.1093/molbev/msab075
Autor:
Vlad Cojocaru, Vikas Malik, Daisylyn Senna Tan, Mingxi Weng, Yogesh Srivastava, Lydia W.T. Cheung, Ralf Jauch, Guangming Wu, Asif Javed, Veeramohan Veerapandian
Publikováno v:
FEBS Journal, 287(1), 122-144. Wiley-Blackwell
The functional consequences of cancer-associated missense mutations are unclear for the majority of proteins. We have previously demonstrated that the activity of SOX and Pit-Oct-Unc (POU) family factors during pluripotency reprogramming can be switc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454c03752ac8a860e61b55539192c5c6
https://hdl.handle.net/20.500.11755/71f1888a-7614-4101-8c39-09d156b776c5
https://hdl.handle.net/20.500.11755/71f1888a-7614-4101-8c39-09d156b776c5
Autor:
Lifang Han, Xianwei Chen, Youshan Heng, Mingjie Zhang, Mingxi Weng, Zeyu Shen, Gang Wang, Zhenguo Wu, Shaopu Zhou, Xinrong Fu, Han Zhu
Publikováno v:
Proc Natl Acad Sci U S A
Significance This work investigated the in vivo role of Paxbp1, a poorly studied nuclear protein, in regulating adult mouse muscle stem cells (MuSCs). By deleting Paxbp1 in adult mouse quiescent MuSCs, we found that Paxbp1 -null MuSCs were unable to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05482208dd4c9c72f7084902b72b48c5
https://doi.org/10.1073/pnas.2021093118
https://doi.org/10.1073/pnas.2021093118
Autor:
Zahir Shah, Sebastian Pott, Dennis Zimmer, Vikas Malik, Veeramohan Veerapandian, Miguel A. Esteban, Sergiy Velychko, Markus Holzner, Marius Arend, Mingxi Weng, Sebastiaan H. Meijsing, Yogesh Srivastava, Ralf Jauch, Laura V. Glaser, Yanpu Chen, Andrew P. Hutchins, Huating Wang, Jiekai Chen, Hans R. Schöler
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Oct4, along with Sox2 and Klf4 (SK), can induce pluripotency but structurally similar factors like Oct6 cannot. To decode why Oct4 has this unique ability, we compare Oct4-binding, accessibility patterns and transcriptional waves with Oct6 and an Oct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95564dd529158482eb3683b451d2c99d
https://hdl.handle.net/21.11116/0000-0005-9084-221.11116/0000-0005-9086-0
https://hdl.handle.net/21.11116/0000-0005-9084-221.11116/0000-0005-9086-0
Autor:
Xiaoxiao Yang, Ralf Jauch, Veeramohan Veerapandian, Vikas Malik, Yogesh Srivastava, Jan Ole Ackermann, Mingxi Weng
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 11, Iss 2, Pp 593-606 (2018)
Stem Cell Reports, Vol 11, Iss 2, Pp 593-606 (2018)
Summary Directed biomolecular evolution is widely used to tailor and enhance enzymes, fluorescent proteins, and antibodies but has hitherto not been applied in the reprogramming of mammalian cells. Here, we describe a method termed directed evolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb40b4c5441633a831a5ee2d58671cc
https://pubmed.ncbi.nlm.nih.gov/30078555
https://pubmed.ncbi.nlm.nih.gov/30078555
Autor:
Shaopu Zhou, Lifang Han, Mingxi Weng, Han Zhu, Youshan Heng, Gang Wang, Zeyu Shen, Xianwei Chen, Xinrong Fu, Mingjie Zhang, Zhenguo Wu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 3/30/2021, Vol. 118 Issue 13, p1-12, 12p