Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mingtan Tang"'
Publikováno v:
Toxicology Communications, Vol 6, Iss 1, Pp 30-34 (2022)
AbstractIntroduction Our study investigated whether lipid emulsion therapy could act as an antidote for intravenous amiodarone toxicity in a rat model.Methods 20 rats were randomised to receive lipid emulsion (ILE) or saline. Rats were infused with a
Externí odkaz:
https://doaj.org/article/a44cd5b2180742c9940dd1ed4a0079a9
Autor:
Joy N. Reginald-Opara, Darren Svirskis, Song Yee Paek, Mingtan Tang, Simon J. O'Carroll, Justin M. Dean, Lawrence W. Chamley, Zimei Wu
Publikováno v:
Materials Today Bio, Vol 13, Iss , Pp 100212- (2022)
Despite the demonstrated effectiveness of nano-materials for drug delivery to the brain, a comprehensive understanding of their transport processes across the blood brain barrier (BBB) remains undefined. This multidisciplinary study aimed to gain an
Externí odkaz:
https://doaj.org/article/d4808d2f0dc0461a9ab958e26a05d8f9
Publikováno v:
Pharmaceutics, Vol 13, Iss 3, p 395 (2021)
In recent years, a number of groups have been investigating the use of “empty” liposomes with no drug loaded as scavengers both for exogenous intoxicants and endogenous toxic molecules. Preclinical trials have demonstrated that repurposing liposo
Externí odkaz:
https://doaj.org/article/0da581de6b514275b834a16b9165afba
Publikováno v:
Pharmaceutical Development and Technology. 26:1000-1009
Conventional non-pH-sensitive liposomes for cytoplasmic delivery of protein suffer from poor efficiency. Here we investigated mannosylated pH-sensitive liposomes (MAN-PSL) for cytoplasmic delivery of protein to macrophages RAW 264.7 using PSL and non
Publikováno v:
International journal of pharmaceutics. 626
Notwithstanding the growing evidence of improved drug delivery efficiency to the brain by ligand modification of PEGylated liposomes, the comprehensive knowledge of their transport processes and payload across the BBB is yet to be revealed. Herein, t
Publikováno v:
RSC Advances. 10:19089-19105
Breast cancer stem(-like) cells (BCSCs) have been found to be responsible for therapeutic resistance and disease relapse. BCSCs are difficult to eradicate due to their high resistance to conventional treatments and high plasticity. Functionalised nan
Autor:
Mimi M. Yang, Sasi Bhushan Yarragudi, Stephen M. F. Jamieson, Mingtan Tang, William R. Wilson, Zimei Wu
Publikováno v:
Pharmaceutical research. 39(6)
While delivery of chemotherapeutics to cancer cells by nanomedicines can improve therapeutic outcomes, many fail due to the low drug loading (DL), poor cellular uptake and endosomal entrapment. This study investigated the potential to overcome these
Autor:
Joy N. Reginald-Opara, Darren Svirskis, Song Yee Paek, Mingtan Tang, Simon J. O'Carroll, Justin M. Dean, Lawrence W. Chamley, Zimei Wu
Publikováno v:
Materials Today Bio, Vol 13, Iss, Pp 100212-(2022)
Despite the demonstrated effectiveness of nano-materials for drug delivery to the brain, a comprehensive understanding of their transport processes across the blood brain barrier (BBB) remains undefined. This multidisciplinary study aimed to gain an
Publikováno v:
International Journal of Pharmaceutics. 626:122153
Small extracellular vesicles (sEVs) have emerged as attractive drug delivery systems. However, the intracellular release of their cargoes is restricted. This study aimed to develop an efficient approach to re-engineer sEVs by hybridisation with pH-se
Publikováno v:
Pharmaceutics, Vol 13, Iss 395, p 395 (2021)
Pharmaceutics
Pharmaceutics
In recent years, a number of groups have been investigating the use of “empty” liposomes with no drug loaded as scavengers both for exogenous intoxicants and endogenous toxic molecules. Preclinical trials have demonstrated that repurposing liposo