Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Mingshan Niu"'
Autor:
Tongxuan Guo, Changyong Wu, Lingni Zhou, Junhao Zhang, Wanzhou Wang, Yang Shen, Ludong Zhang, Mingshan Niu, Xu Zhang, Rutong Yu, Xuejiao Liu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Glioblastoma (GBM) is a brain tumor with the highest level of malignancy and the worst prognosis in the central nervous system. Mitochondrial metabolism plays a vital role in the occurrence and development of cancer, which provide
Externí odkaz:
https://doaj.org/article/b0754ccd0c3a447f8ba401fe3b0a4ab6
Publikováno v:
Hematology, Vol 28, Iss 1 (2023)
ABSTRACTBackground: Clinical outcome of patients with chronic myeloid leukemia (CML) has improved dramatically since the introduction of tyrosine kinase inhibitors such as imatinib mesylate (IM). However, approximately 20-30% of patients experience I
Externí odkaz:
https://doaj.org/article/7ad297ee06d841d0b29d389c63a0a7c9
Autor:
Guanzheng Liu, Jiefeng Yu, Runqiu Wu, Lin Shi, Xu Zhang, Wanhong Zhang, Xiaomin Zhong, Yifeng Wang, Huan Li, Yang Shen, Changyong Wu, Rutong Yu, Mingshan Niu, Xuejiao Liu
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/06880ced148c45e88c88053adefa7f0a
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Acute myeloid leukemia (AML) is an aggressive hematologic malignancy with high mortality that urgently requires new treatments. ROCK1 plays an essential role in regulating growth and survival in AML cells. In this study, we evaluated GSK269962A, a se
Externí odkaz:
https://doaj.org/article/b3df557efa5d45a4ada7ab54a73b042d
Autor:
Guanzheng Liu, Jiefeng Yu, Runqiu Wu, Lin Shi, Xu Zhang, Wanhong Zhang, Xiaomin Zhong, Yifeng Wang, Huan Li, Yang Shen, Changyong Wu, Rutong Yu, Mingshan Niu, Xuejiao Liu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-13 (2021)
Abstract Glioblastoma multiforme (GBM) is an extremely aggressive brain tumor for which new therapeutic approaches are urgently required. Unfolded protein response (UPR) plays an important role in the progression of GBM and is a promising target for
Externí odkaz:
https://doaj.org/article/686657be80554fa58d87c62f380f9f6d
Autor:
Xuejiao Liu, Yiming Tu, Yifeng Wang, Di Zhou, Yulong Chong, Lin Shi, Guanzheng Liu, Xu Zhang, Sijin Wu, Huan Li, Shangfeng Gao, Mingshan Niu, Rutong Yu
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Activation of nuclear factor-kappa B (NF-κΒ) through DNA damage is one of the causes of tumor cell resistance to radiotherapy. Chromosome region 1 (CRM1) regulates tumor cell proliferation, drug resistance, and radiation resista
Externí odkaz:
https://doaj.org/article/403d076e5b3d423698adbf67970d7385
Autor:
Lin Shi, Huize Liu, Yifeng Wang, Yulong Chong, Jie Wang, Guanzheng Liu, Xu Zhang, Xiangyu Chen, Huan Li, Mingshan Niu, Jun Liang, Rutong Yu, Xuejiao Liu
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Switch-associated protein 70 (SWAP-70) is a guanine nucleotide exchange factor that is involved in cytoskeletal rearrangement and regulation of migration and invasion of malignant tumors. However, the mechanism by which SWAP-70 re
Externí odkaz:
https://doaj.org/article/cc43cc565cdf41ba8aece8018e766d8e
Autor:
Xuejiao Liu, Xiangyu Chen, Lin Shi, Qianqian Shan, Qiyu Cao, Chenglong Yue, Huan Li, Shengsheng Li, Jie Wang, Shangfeng Gao, Mingshan Niu, Rutong Yu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Glioblastoma (GBM) is a fatal brain tumor, lacking effective treatment. Epidermal growth factor receptor (EGFR) is recognized as an attractive target for GBM treatment. However, GBMs have very poor responses to the first- and seco
Externí odkaz:
https://doaj.org/article/9ff8f18883c842dbaf80e4363393a3e6
Autor:
Huihui Zhang, Ninghan Zhang, Rong Wang, Tingting Shao, Yuan Feng, Yao Yao, Qingyun Wu, Shengyun Zhu, Jiang Cao, Huanxin Zhang, Zhenyu Li, Xuejiao Liu, Mingshan Niu, Kailin Xu
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background Acute myeloid leukemia (AML) is a highly heterogeneous malignancy with various outcomes, and therefore needs better risk stratification tools to help select optimal therapeutic options. Methods In this study, we identify miRNAs th
Externí odkaz:
https://doaj.org/article/e6809d5683fc400e9f4eb39452b07a16
Autor:
Chen Yang, Tingting Shao, Huihui Zhang, Ninghan Zhang, Xiaoying Shi, Xuejiao Liu, Yao Yao, Linyan Xu, Shengyun Zhu, Jiang Cao, Hai Cheng, Zhiling Yan, Zhenyu Li, Mingshan Niu, Kailin Xu
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background Acute myeloid leukemia (AML) is a highly heterogeneous disease. MicroRNAs function as important biomarkers in the clinical prognosis of AML. Methods This study identified miR-425 as a prognostic factor in AML by screening the TCGA
Externí odkaz:
https://doaj.org/article/ca3c49855a054f88a95fa08a31732863