Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Mingrui Zhu"'
Autor:
Buse Eglenen-Polat, Ryan R. Kowash, Hai-Cheng Huang, Silvia Siteni, Mingrui Zhu, Kenian Chen, Matthew E. Bender, Ilgen Mender, Victor Stastny, Benjamin J. Drapkin, Prithvi Raj, John D. Minna, Lin Xu, Jerry W. Shay, Esra A. Akbay
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract There are few effective treatments for small cell lung cancer (SCLC) underscoring the need for innovative therapeutic approaches. This study focuses on exploiting telomerase, a critical SCLC dependency as a therapeutic target. A prominent ch
Externí odkaz:
https://doaj.org/article/d143811484044c1b88f499b5d0432d04
Publikováno v:
Biomimetics, Vol 9, Iss 1, p 28 (2024)
Steel strip is an important raw material for the engineering, automotive, shipbuilding, and aerospace industries. However, during the production process, the surface of the steel strip is prone to cracks, pitting, and other defects that affect its ap
Externí odkaz:
https://doaj.org/article/170efd07dd564f958c7f9d32883d0614
Publikováno v:
Shipin gongye ke-ji, Vol 43, Iss 1, Pp 351-358 (2022)
To investigate the effects of Altay lipid and its extract on liver lipid level and oxidative stress in mice, 84 Kunming mice were randomly divided into two batches of 20 days and 40 days, 7 groups each (n=6): blank group (basic feed feeding), rapesee
Externí odkaz:
https://doaj.org/article/5bdfc2e857084e469e3bb158fc2d8417
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Previous researches indicated that emotional regulation can be associated with depression and anxiety, which may be an important mediating factor between emotional regulation and internet addiction. However, the mechanism between these associations h
Externí odkaz:
https://doaj.org/article/4b3b1871bd0e4905abefc5b7c50720ba
Autor:
Juan J. Miret, Paul Kirschmeier, Shohei Koyama, Mingrui Zhu, Yvonne Y. Li, Yujiro Naito, Min Wu, Venkat S. Malladi, Wei Huang, William Walker, Sangeetha Palakurthi, Glenn Dranoff, Peter S. Hammerman, Chad V. Pecot, Kwok-Kin Wong, Esra A. Akbay
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Background Tumor orchestrated metabolic changes in the microenvironment limit generation of anti-tumor immune responses. Availability of arginine, a semi-essential amino acid, is critical for lymphocyte proliferation and function. Levels of
Externí odkaz:
https://doaj.org/article/78dba48bba534719a4cc483ade3990dd
Autor:
Bin Liu, Shangwen Jiang, Min Li, Xuelian Xiong, Mingrui Zhu, Duanzhuo Li, Lei Zhao, Lili Qian, Linhui Zhai, Jing Li, Han Lu, Shengnan Sun, Jiandie Lin, Yan Lu, Xiaoying Li, Minjia Tan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Ubiquitin-specific protease 14 (USP14) is a proteasome-associated deubiquitinating enzyme with known roles in physiology and disease. Here the authors show that fatty acid synthase (FASN) is a substrate of USP14, and that by stabilizing FASN, it play
Externí odkaz:
https://doaj.org/article/3581473922f6403895adb5219d0ee52b
Publikováno v:
Complexity, Vol 2021 (2021)
circRNA is a novel class of noncoding RNA with closed-loop structure. Increasing biological experiments have shown that circRNAs play an important role in many diseases by acting as a miRNA sponge to indirectly regulate the expression of miRNA target
Externí odkaz:
https://doaj.org/article/e80b1e81fc2e4b6090b4fa1af8371c83
Autor:
Zhongya Sun, Hao Zhang, Yuanyuan Zhang, Liping Liao, Wen Zhou, Fengcai Zhang, Fulin Lian, Jing Huang, Pan Xu, Rukang Zhang, Wenchao Lu, Mingrui Zhu, Hongru Tao, Feng Yang, Hong Ding, Shijie Chen, Liyan Yue, Bing Zhou, Naixia Zhang, Minjia Tan, Hualiang Jiang, Kaixian Chen, Bo Liu, Chuanpeng Liu, Yongjun Dang, Cheng Luo
Publikováno v:
Advanced Science, Vol 7, Iss 14, Pp n/a-n/a (2020)
Abstract The Rho family GTPases are crucial drivers of tumor growth and metastasis. However, it is difficult to develop GTPases inhibitors due to a lack of well‐characterized binding pockets for compounds. Here, through molecular dynamics simulatio
Externí odkaz:
https://doaj.org/article/2e4dbc3d2ae14c49977b0ef0da5f68ca
Autor:
Hitoshi Shiota, Sophie Barral, Thierry Buchou, Minjia Tan, Yohann Couté, Guillaume Charbonnier, Nicolas Reynoird, Fayçal Boussouar, Matthieu Gérard, Mingrui Zhu, Lisa Bargier, Denis Puthier, Florent Chuffart, Ekaterina Bourova-Flin, Sarah Picaud, Panagis Filippakopoulos, Afsaneh Goudarzi, Ziad Ibrahim, Daniel Panne, Sophie Rousseaux, Yingming Zhao, Saadi Khochbin
Publikováno v:
Cell Reports, Vol 24, Iss 13, Pp 3477-3487.e6 (2018)
Summary: Nuclear protein in testis (Nut) is a universal oncogenic driver in the highly aggressive NUT midline carcinoma, whose physiological function in male germ cells has been unclear. Here we show that expression of Nut is normally restricted to p
Externí odkaz:
https://doaj.org/article/df3c3fd21a274a8b95f2d28fef81b222
Publikováno v:
IEEE Transactions on Image Processing. 32:483-495