Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mingquan Su"'
Publikováno v:
Journal of International Medical Research, Vol 49 (2021)
Objectives To investigate the association between poly(ADP-ribose) polymerase 1 ( PARP1 ) rs1136410 Val762Ala and cancer risk in Asian populations, as published findings remain controversial. Methods The PubMed and EMBASE databases were searched, and
Externí odkaz:
https://doaj.org/article/a723fd5734d645d7a1dc85fe099899f0
Publikováno v:
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. 37(7)
To analyze the clinical phenotype and genetic basis of a consanguineous pedigree affected with hereditary coagulation factor XII (FXII) deficiency.Following extraction of genomic DNA, all exons and flanking regions of F12 gene were subjected to PCR a
Autor:
Zhuo Li, Mingquan Su, Yi Xu, Wei-Xiao Fan, Yun Ye, Yang Ji, Juan Wang, La-Xiu Li, Su-Liang Li, Yueyun Ma, Yanjun Diao, Liu Yang, Lin Lei, Xiaoke Hao
Publikováno v:
Oncotarget
// Yun Ye 1, 2, * , Su-Liang Li 2, * , Yue-Yun Ma 1 , Yan-Jun Diao 1 , Liu Yang 1 , Ming-Quan Su 1 , Zhuo Li 2 , Yang Ji 3 , Juan Wang 1 , Lin Lei 1 , Wei-Xiao Fan 1 , La-Xiu Li 1 , Yi Xu 1 and Xiao-Ke Hao 1 1 Department of Laboratory Medicine, Xijin
Autor:
Bin Xu, Yueyun Ma, Mingquan Su, Xiaoke Hao, Yuqi Yang, Yunfeng Xiao, Jianbing Ding, Yanhua Li, Wenfang He, Liu Yang
Publikováno v:
Frontiers in Laboratory Medicine, Vol 1, Iss 1, Pp 16-26 (2017)
Background: We analyzed respiratory tract bacterial flora in patients with influenza H1N1 virus infection, and investigated the role of H1N1 virus in secondary bacterial infection. Method: A total of 12,766 operational taxonomic units (OTUs) were obt
Publikováno v:
Genetics and molecular research : GMR. 15(2)
The widespread use of antifungal agents has led to increasing azole resistance in Candida species. A major azole-resistance mechanism involves point mutations in the ERG11 gene, which encodes cytochrome P450 lanosterol 14a-demethylase. In this study,
Publikováno v:
Cancer biologytherapy. 17(5)
Specific and efficient delivery of siRNA into intended tumor cells remains as a challenge, even though RNAi has been exploited as a new strategy for prostate cancer therapy. This work aims to address both specificity and efficiency of SURVIVIN-siRNA
Autor:
Mingquan Su, Yin Long, Yinye Miao, Qing Zhang, Hua Han, Jiayun Liu, Xiaoke Hao, Jian-Jun Shen
Publikováno v:
Acta Biochimica et Biophysica Sinica. 41:223-230
Survivin, a member of inhibitor of apoptosis family protein, has become an attractive therapeutic target in cancer due to its selective expression in tumor cells and its important roles for tumor cell viability. Here, we show that vector-based small
The programmed death-1 (PD-1)/PD-ligand 1 (PD-L1) signaling pathway is a negative regulatory mechanism that inhibits T cell proliferation and cytokine production. Soluble PD-1 (sPD-1) and soluble PD-L1 (sPD-L1), are also involved in regulation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5629a46fbc62375c5c6565ab0b61e721
https://europepmc.org/articles/PMC4726854/
https://europepmc.org/articles/PMC4726854/
Autor:
Guo-qiang Bao, Jiayun Liu, Qing Zhang, Jing Yi, Jian-Jun Shen, Xiaoke Hao, Mingquan Su, Sihe Zhang
Publikováno v:
Cancer Immunology, Immunotherapy. 56:477-489
The HAMA response is a major challenge when murine antibodies are repeatedly administered for antibody directed enzyme prodrug therapy in vivo. In this study we have achieved humanization of the anti-gamma-seminoprotein E(4)B(7) murine mAb by guided
Autor:
Jiayun Liu, Xiaoke Hao, Mingquan Su, Lei Zhou, Yijuan Xin, Yueyun Ma, Feng Liu, Qing Zheng, Xiao-dong Cheng, Jiacuo Danzheng, Xian-Fei Zeng, Liu Yang
Publikováno v:
International journal of antimicrobial agents. 46(1)
Two-component systems (TCSs) have been reported to exhibit a sensing and responding role under drug stress that induces drug resistance in several bacterial species. However, the relationship between TCSs and multidrug resistance in Mycobacterium tub