Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Minglu Zhou"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The binding of therapeutic antagonists to their receptors often fail to translate into adequate manipulation of downstream pathways. To fix this ‘bug’, here we report a strategy that stitches cell surface ‘patches’ to promote recepto
Externí odkaz:
https://doaj.org/article/b78e36ce8f314155ad7b49ce002ad5f5
Autor:
Bo Li, Ping Zhang, Junlin Li, Rui Zhou, Minglu Zhou, Chendong Liu, Xi Liu, Liqiang Chen, Lian Li
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Allogeneic tumor cell vaccines provide off‐the‐shelf convenience but lack patient specificity due to heterogeneity in tumor antigens. Here, allogeneic tumor cell corpses are converted into “zombie cells” capable of assimilating heter
Externí odkaz:
https://doaj.org/article/d7739c8a245740c5844dc37d5e213e60
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 8, Pp 3383-3397 (2022)
Tumor recurrence and metastasis is the leading cause of mortality for postoperative breast cancer patients. However, chemotherapy intervention after surgery is often unsatisfactory, because residual microtumors are difficult to target and require fre
Externí odkaz:
https://doaj.org/article/488e5bad9501467ca81a6b39848ac6b2
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 3, Pp 615-625 (2019)
Multidrug resistance (MDR) has been considered as a huge challenge to the effective chemotherapy. Therefore, it is necessary to develop new strategies to effectively overcome MDR. Here, based on the previous research of N-(2-hydroxypropyl)methacrylam
Externí odkaz:
https://doaj.org/article/94837da0296b4685875d18bcd9d6bf49
Publikováno v:
Advanced Science, Vol 8, Iss 4, Pp n/a-n/a (2021)
Abstract Mitochondria are highly involved in the metastasis of cancer cells. However, low permeability of mitochondria impedes the entry of anti‐cancer drugs. Here, a self‐assembled nanoparticle platform is designed that not only targets the DNA
Externí odkaz:
https://doaj.org/article/541e7700f0be4ab982a29dd31a3b27ae
Publikováno v:
Nano Research. 15:3446-3457
Publikováno v:
Nano Research. 15:3376-3386
Mitochondria are highly involved in the metastasis of cancer cells. However, tumor cells impede the efficiency of mitochondrial targeted drugs by protecting mitochondria through an intrinsic and adaptive antioxidant mechanism. We aim to disturb the r
Publikováno v:
ACS nano. 16(4)
Tumor surgery can create an inflammatory trauma to aggravate residual tumor "seed" to colonize pre-metastatic niches (PMNs) "soil" at secondary sites, thereby promoting post-operative metastasis. However, two-pronged strategies for post-surgical elim
Publikováno v:
Nanoscale. 14(12)
Pre-metastatic initiation is essential in tumor metastasis, and the inhibition of it could prevent the spread of cancers to distant organs. Both tumor-associated macrophages (TAMs) and the epithelial-mesenchymal transition (EMT) play an important rol
Autor:
Rui Zhou, Jiatao Yang, Yucheng Xiang, Yuan Huang, Qiuyi Li, Minglu Zhou, Dandan Xie, Xi Lin, Zhou Zhou
Publikováno v:
Journal of Materials Chemistry B. 9:1336-1350
Distant organ metastasis is the main cause of death in breast cancer patients. Evidences have shown that mitochondria also play a crucial role in tumor metastasis, except for as apoptosis center. However, the treatment of tumor growth and metastasis