Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Minglong Qiu"'
Autor:
Minglong Qiu, Leilei Chang, Guoqing Tang, Wenkai Ye, Yiming Xu, Nijiati Tulufu, Zhou Dan, Jin Qi, Lianfu Deng, Changwei Li
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 7, Pp 1574-1590 (2024)
Abstract The hypoxia-inducible factor-1α (HIF-1α) pathway coordinates skeletal bone homeostasis and endocrine functions. Activation of the HIF-1α pathway increases glucose uptake by osteoblasts, which reduces blood glucose levels. However, it is u
Externí odkaz:
https://doaj.org/article/8a448bbb63684992b2a95ecce48a1c24
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32889- (2024)
Osteocytes are terminally differentiated cells derived from osteoblasts and are deeply embedded within the bone matrix. They play a critical role in bone remodeling by generating a lacuno-canalicular network (LCN) and controlling the transport of nut
Externí odkaz:
https://doaj.org/article/dc1e3b6482b849f6b112f361c15a42d7
Autor:
Zhengwei Cai, Zhijie Chen, Yuan Tang, Liang Cheng, Minglong Qiu, Ningtao Wang, Wei Jiang, Zhanchun Li, Catarina Leite Pereira, Yunhai Zhang, Bruno Sarmento, Wenguo Cui
Publikováno v:
Small Science, Vol 4, Iss 6, Pp n/a-n/a (2024)
Significance of endogenous mineralization in bone reconstruction is paramount, as it facilitates the accumulation of calcium ions for bone tissue deposition. However, conventional 3D‐printed scaffolds lack the capacity for calcium ion enrichment an
Externí odkaz:
https://doaj.org/article/204e3e97b1ee4b1cacfc315267dcecec
Publikováno v:
Advanced Science, Vol 11, Iss 1, Pp n/a-n/a (2024)
Abstract A fundamental understanding of inflammation and tissue healing suggests that the precise regulation of the inflammatory phase, both in terms of location and timing, is crucial for bone regeneration. However, achieving the activation of early
Externí odkaz:
https://doaj.org/article/dcc004e7351e439daa345333309eb86c
Autor:
Zhijie Chen, Mengyuan Lv, Jing Liang, Kai Yang, Fan Li, Zhi Zhou, Minglong Qiu, Haoyi Chen, Zhengwei Cai, Wenguo Cui, Zhanchun Li
Publikováno v:
Advanced Science, Vol 10, Iss 33, Pp n/a-n/a (2023)
Abstract Postmenopausal osteoporosis (PMO) is often accompanied by neuroendocrine changes in the hypothalamus, which closely associates with the microbial diversity, community composition, and intestinal metabolites of gut microbiota (GM). With the e
Externí odkaz:
https://doaj.org/article/abcec11047bd41cbac86c46bae0092fe
Autor:
Minglong Qiu, Changwei Li, Zhengwei Cai, Cuidi Li, Kai Yang, Nijiati Tulufu, Bo Chen, Liang Cheng, Chengyu Zhuang, Zhihong Liu, Jin Qi, Wenguo Cui, Lianfu Deng
Publikováno v:
Advanced Science, Vol 10, Iss 16, Pp n/a-n/a (2023)
Abstract The formation of a calcified cartilaginous callus (CACC) is crucial during bone repair. CACC can stimulate the invasion of type H vessels into the callus to couple angiogenesis and osteogenesis, induce osteoclastogenesis to resorb the calcif
Externí odkaz:
https://doaj.org/article/53da85b6621043ee9ecc74aad7683b23
Autor:
Kaizhe Chen, Jian Zhao, Minglong Qiu, Lianfang Zhang, Kai Yang, Leilei Chang, Peng Jia, Jin Qi, Lianfu Deng, Changwei Li
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
The activation of hypoxia-inducible factor 1α (HIF-1α) signaling has promising implications for the treatment of bone diseases such as osteoporosis and skeletal fractures. However, the effects of manipulating HIF-1α pathway on bone micro-structure
Externí odkaz:
https://doaj.org/article/b7e13136b31446e687a22bcf8fd5a4b7
Autor:
Changwei Li, Minglong Qiu, Leilei Chang, Jin Qi, Lianfang Zhang, Bernhard Ryffel, Lianfu Deng
Publikováno v:
Cell Death & Differentiation. 29:1123-1136
Bone homeostasis is maintained through a balance of bone formation by osteoblasts and bone resorption by osteoclasts. Ubiquitin-specific proteases (USPs) are involved in regulating bone metabolism by preserving bone formation or antagonizing bone res
Autor:
Zhijie, Chen, Lianlian, Wang, Changjun, Guo, Minglong, Qiu, Liang, Cheng, Kaizhe, Chen, Jin, Qi, Lianfu, Deng, Chuan, He, Xinming, Li, Yufei, Yan
Publikováno v:
SSRN Electronic Journal.
Wound repair involves a sophisticated process that includes angiogenesis, immunoregulation and collagen deposition. However, weak revascularization performance and the lack of biochemical cues to trigger immunomodulatory function currently limit biom
Autor:
Ce Ji, Minglong Qiu, Huitong Ruan, Cuidi Li, Liang Cheng, Juan Wang, Changwei Li, Jin Qi, Wenguo Cui, Lianfu Deng
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(8)
Three dimension (3D) printed scaffolds have been shown to be superior in promoting tissue repair, but the cell-level specific regulatory network activated by 3D printing scaffolds with different material components to form a symbiosis niche have not