Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Minglong, Cai"'
Autor:
Yujun Sheng, Jiali Zhang, Keke Li, Hongyan Wang, Wenjun Wang, Leilei Wen, Jinping Gao, Xianfa Tang, Huayang Tang, He Huang, Minglong Cai, Tao Yuan, Lu Liu, Xiaodong Zheng, Zhengwei Zhu, Yong Cui
Publikováno v:
FEBS Open Bio, Vol 11, Iss 2, Pp 395-403 (2021)
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by abnormal activation of T cells and caused by an imbalance in the production and clearance of apoptotic cells. We previously showed that the transcription regulator Ba
Externí odkaz:
https://doaj.org/article/2143e338bf8040c5978eaf4f37243b3b
Publikováno v:
Journal of Bio-X Research, Vol 2, Iss 4, Pp 153-158 (2019)
Abstract. Many common diseases are characterized by polygenic architectures in which a single variant has only a small effect on phenotype. Genome-wide association studies and next generation sequencing have identified thousands of genetic variants o
Externí odkaz:
https://doaj.org/article/cdc71678241d45b289cbea553c872ff6
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is characterized by the inflammation of small and medium vessels and presence of proteinase 3-ANCA or myeloperoxidase-ANCA in the circulation. AAV comprises three clinical subtype
Externí odkaz:
https://doaj.org/article/85e230ada8024a19ae3f7528a67b49d0
Autor:
Minglong Cai, Tao Yuan, He Huang, Lan Gui, Li Zhang, Ziyuan Meng, Wenjuan Wu, Yujun Sheng, Xuejun Zhang
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Vitiligo is a multifactorial polygenic disorder, characterized by acquired depigmented skin and overlying hair resulting from the destruction of melanocytes. Genome-wide association studies (GWASs) of vitiligo have identified approximately 100 geneti
Externí odkaz:
https://doaj.org/article/664507a7d1c84642a40a801ee8e714d5
Autor:
Minglong Cai, He Huang, Zhulin Hu, Tao Yuan, Weiran Li, Yaoguang Liu, Lijun Zheng, Yan Zhang, Yujun Sheng, Xuejun Zhang
Publikováno v:
International Journal of Genomics, Vol 2020 (2020)
Psoriasis is a multifactorial immune-mediated skin disease with a strong genetic background. Previous studies reported that psoriasis with a family history (PFH) and sporadic psoriasis (SP) have a distinct manifestation and genetic predisposition. Ho
Externí odkaz:
https://doaj.org/article/cf1ce2751a774620ac20cf69b3c38a7f
Autor:
Xianyong, Yin, Kwangwoo, Kim, Hiroyuki, Suetsugu, So-Young, Bang, Leilei, Wen, Masaru, Koido, Eunji, Ha, Lu, Liu, Yuma, Sakamoto, Sungsin, Jo, Rui-Xue, Leng, Nao, Otomo, Young-Chang, Kwon, Yujun, Sheng, Nobuhiko, Sugano, Mi Yeong, Hwang, Weiran, Li, Masaya, Mukai, Kyungheon, Yoon, Minglong, Cai, Kazuyoshi, Ishigaki, Won Tae, Chung, He, Huang, Daisuke, Takahashi, Shin-Seok, Lee, Mengwei, Wang, Kohei, Karino, Seung-Cheol, Shim, Xiaodong, Zheng, Tomoya, Miyamura, Young Mo, Kang, Dongqing, Ye, Junichi, Nakamura, Chang-Hee, Suh, Yuanjia, Tang, Goro, Motomura, Yong-Beom, Park, Huihua, Ding, Takeshi, Kuroda, Jung-Yoon, Choe, Chengxu, Li, Hiroaki, Niiro, Youngho, Park, Changbing, Shen, Takeshi, Miyamoto, Ga-Young, Ahn, Wenmin, Fei, Tsutomu, Takeuchi, Jung-Min, Shin, Keke, Li, Yasushi, Kawaguchi, Yeon-Kyung, Lee, Yong-Fei, Wang, Koichi, Amano, Dae Jin, Park, Wanling, Yang, Yoshifumi, Tada, Yu Lung, Lau, Ken, Yamaji, Zhengwei, Zhu, Masato, Shimizu, Takashi, Atsumi, Akari, Suzuki, Takayuki, Sumida, Yukinori, Okada, Koichi, Matsuda, Keitaro, Matsuo, Yuta, Kochi, Kazuhiko, Yamamoto, Koichiro, Ohmura, Tae-Hwan, Kim, Sen, Yang, Takuaki, Yamamoto, Bong-Jo, Kim, Nan, Shen, Shiro, Ikegawa, Hye-Soon, Lee, Xuejun, Zhang, Chikashi, Terao, Yong, Cui, Sang-Cheol, Bae
Publikováno v:
Annals of the Rheumatic Diseases. 81:1273-1280
ObjectiveGenome-wide association studies (GWAS) have identified >100 risk loci for systemic lupus erythematosus (SLE), but the disease genes at most loci remain unclear, hampering translation of these genetic discoveries. We aimed to prioritise genes
Autor:
Yeon-Kyung Lee, Kohei Karino, Dae Jin Park, Xiaoting Chen, Xiaodong Zheng, Dong-Qing Ye, So-Young Bang, Leilei Wen, Tae-Hwan Kim, Takuaki Yamamoto, Yukinori Okada, Young Mo Kang, Sreeja Parameswaran, Xuejun Zhang, Cheng-Xu Li, Eunji Ha, Sang Cheol Bae, Hiroyuki Suetsugu, Koichi Amano, Tsutomu Takeuchi, Takayuki Sumida, Ken Yamaji, Hye-Soon Lee, Yuanjia Tang, Seung-Cheol Shim, Viktoryia Laurynenka, Sen Yang, Wanling Yang, Yujun Sheng, Xianyong Yin, Koichi Matsuda, Keitaro Matsuo, Akari Suzuki, Chang-Hee Suh, Weiran Li, Kwangwoo Kim, Lu Liu, Kyungheon Yoon, Bong-Jo Kim, Mi Yeong Hwang, Takeshi Kuroda, Shruti Eswar, Koichiro Ohmura, Keke Li, Tomoya Miyamura, Shiro Ikegawa, Hanan Salim, Yuta Kochi, Chikashi Terao, Won Tae Chung, Sungsin Jo, Changbing Shen, Kazuhiko Yamamoto, Daisuke Takahashi, Mengwei Wang, Masaya Mukai, Minglong Cai, Matthew T. Weirauch, Nao Otomo, Kazuyoshi Ishigaki, Yuma Sakamoto, Nan Shen, Hiroaki Niiro, Takashi Atsumi, Yong-Fei Wang, Junichi Nakamura, Young-Chang Kwon, Leah C. Kottyan, Yong Cui, John B. Harley, Goro Motomura, Masato Shimizu, Yasushi Kawaguchi, Nobuhiko Sugano, Rui-Xue Leng, Jung-Yoon Choe, Takeshi Miyamoto, Yong Beom Park, Jung-Min Shin, Masaru Koido, G.Y. Ahn, Huihua Ding, Wen-Min Fei, Shin-Seok Lee, Young-Ho Park, He Huang, Yoshifumi Tada
Publikováno v:
Annals of the Rheumatic Diseases
ObjectiveSystemic lupus erythematosus (SLE), an autoimmune disorder, has been associated with nearly 100 susceptibility loci. Nevertheless, these loci only partially explain SLE heritability and their putative causal variants are rarely prioritised,
Autor:
Lu Liu, Minglong Cai, Huayang Tang, Yong Cui, Hongyan Wang, Wenjun Wang, He Huang, Jinping Gao, Keke Li, Zhengwei Zhu, Leilei Wen, Xiaodong Zheng, Jiali Zhang, Tao Yuan, Yujun Sheng, Xianfa Tang
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 11, Iss 2, Pp 395-403 (2021)
FEBS Open Bio, Vol 11, Iss 2, Pp 395-403 (2021)
Bach2 is closely associated with systemic lupus erythematosus (SLE). Peripheral blood mononuclear cells and CD4+ T cells of SLE patients exhibit a decrease of Bach2 expression and an increase in the proportions of Th9 cells. Bach2 overexpression repr
Autor:
Minglong Cai, Xuejun Zhang, Yujun Sheng, Xiaojie Hong, Weiran Li, Zhu-Lin Hu, Tao Yuan, He Huang, Lijun Zheng
Publikováno v:
European Journal of Dermatology. 30:554-560
The efficacy and safety of secukinumab, an interleukin-17 inhibitor, as systemic treatment for patients with moderate-to-severe psoriasis have been demonstrated, but real-world data pertaining to this is limited in China. To evaluate the efficacy and
Autor:
Minglong Cai, Yong Cui, Lu Liu, Xue Shen, Ying Qiu, Yujun Sheng, Hui Li, Danfeng Qian, Zhengwei Zhu, Songke Shen, He Huang, Leilei Wen
Publikováno v:
Annals of Human Genetics. 84:221-228
Single-nucleotide polymorphisms (SNPs) in the UHRF gene have been shown to be associated with systemic lupus erythematosus (SLE) in European and Hong Kong Chinese, but statistically significant evidence for association has not been found in a mainlan