Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Mingli Hsieh"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract This study investigated the therapeutic effects of astragaloside IV (AST) on spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD), a neurodegenerative disorder. Human neuroblastoma SK-N-SH cells expressing mutant
Externí odkaz:
https://doaj.org/article/6c3f7f8be7bd4a0b84758276b51aa4a0
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31021- (2024)
Introduction: No markers have been used to diagnose historical peritoneal dialysis (PD)-related peritonitis. Cyclophilin A (CypA) is associated with glucose toxicity and inflammation. We hypothesize that dialysate CypA can be a marker for historical
Externí odkaz:
https://doaj.org/article/37915c1ab0eb438a8900c6ec5247b2bb
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1389 (2022)
Unlike other nuclear factor erythroid-2-related factor 2 (Nrf2) activators, the mechanism of action of curcumin analog, ASC-JM17 (JM17), in regulating oxidative homeostasis remains unknown. Spinocerebellar ataxia type 3 (SCA3) is an inherited polyglu
Externí odkaz:
https://doaj.org/article/5f9d9f3ac7fc4fb090f4d1a86ce5b1c8
Autor:
Mingli Hsieh, Pei-Ju Huang, Pei-Yu Chou, Shih-Wei Wang, Hsi-Chi Lu, Wei-Wen Su, Yuan-Chiang Chung, Min-Huan Wu
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1030 (2022)
Carbonic anhydrase VIII (CAVIII) is a member of the CA family, while CA8 is the oncogene. Here we observed increased expression of CAVIII with high expression in colorectal cancer tissues. CAVIII is also expressed in more aggressive types of human co
Externí odkaz:
https://doaj.org/article/968d3857e18c4de7ba6cdf213a7b0768
Autor:
Jui-Chih Chang, Ko-Hung Liu, Yu-Chi Li, Shou-Jen Kou, Yau-Huei Wei, Chieh-Sen Chuang, Mingli Hsieh, Chin-San Liu
Publikováno v:
Neurosignals, Vol 21, Iss 3-4, Pp 160-173 (2012)
We explored the feasibility of mitochondrial therapy using the cell-penetrating peptide Pep-1 to transfer mitochondrial DNA (mtDNA) between cells and rescue a cybrid cell model of the mitochondrial disease myoclonic epilepsy with ragged-red fibres (M
Externí odkaz:
https://doaj.org/article/c0b29780493649ef83e12a59ed1c3fca
Autor:
Yu-Ling, Wu, Shiuan-Chih, Chen, Jui-Chih, Chang, Wei-Yong, Lin, Chin-Chu, Chen, Chien-Chun, Li, Mingli, Hsieh, Haw-Wen, Chen, Tzu-Yi, Chang, Chin-San, Liu, Kai-Li, Liu
Publikováno v:
Free Radical Biology and Medicine. 195:1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29f3b87bb54053114913f6b20f51885
https://doi.org/10.1016/j.freeradbiomed.2022.12.005
https://doi.org/10.1016/j.freeradbiomed.2022.12.005
Autor:
Guan-Yu Lin, Chung-Yung Ma, Li-Chung Kuo, Benjamin Y. Hsieh, Hanbing Wang, Chin-San Liu, Mingli Hsieh
Publikováno v:
Metabolic Brain Disease. 37:2103-2120
Machado-Joseph disease (MJD), also known as spinocerebellar ataxia type 3 (SCA3), is an autosomal dominant neurodegenerative disease. This disorder is caused by polyglutamine (polyQ)-containing mutant ataxin-3, which tends to misfold and aggregate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d854d55a7d6e9c779580476ed63ecb8
https://doi.org/10.1007/s11011-022-00994-7
https://doi.org/10.1007/s11011-022-00994-7
Publikováno v:
Journal of Neuroscience Research. 97:1278-1297
Machado-Joseph disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) is an inherited neurodegenerative disease that can lead to a regression of motor coordination and muscle control in the extremities. It is known that expansion of CAG repeats encodes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82232b240e9d5b039aeedf7ad45a3854
https://doi.org/10.1002/jnr.24474
https://doi.org/10.1002/jnr.24474
Publikováno v:
Cellular and molecular neurobiology. 41(6)
Carbonic anhydrase 8 (CA8), an isozyme of α-carbonic anhydrases, lacks the ability to catalyze the reversible hydration of CO2 to bicarbonate and proton. Previous studies have shown that single point mutations of CA8, CA8-S100P, and CA8-G162R, are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004fac3024bb44b6469c61f12de9bc7a
https://pubmed.ncbi.nlm.nih.gov/32583043
https://pubmed.ncbi.nlm.nih.gov/32583043
Autor:
Shou Jen Kuo, Ching Liang Hsieh, Hui Ju Chang, Ko Hung Liu, Huei Shin Chang, Wei Yong Lin, Jui Chih Chang, Sheng Fei Chuang, Chin San Liu, Mingli Hsieh, Shin Wu Liu, Ta Tsung Lin, Wen Ling Cheng
Publikováno v:
The Cerebellum. 18:22-32
Spinocerebellar ataxia type 3 (SCA3) is a polyglutamine neurodegenerative disease resulting from the misfolding and accumulation of a pathogenic protein, causing cerebellar dysfunction, and this disease currently has no effective treatments. Far-infr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c9454451b4bf21ad4f478b31f60a6e
https://doi.org/10.1007/s12311-018-0936-3
https://doi.org/10.1007/s12311-018-0936-3