Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Mingjing Shen"'
Autor:
Dantong Sun, Lipin Tan, Yongbing Chen, Qiang Yuan, Kanqiu Jiang, Yangyang Liu, Yuhang Xue, Jinzhi Zhang, Xianbao Cao, Minzhao Xu, Yang Luo, Zhonghua Xu, Zhonghen Xu, Weihua Xu, Mingjing Shen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background Lung cancer remains one of the most prevalent cancer types worldwide, with a high mortality rate. Upregulation of programmed cell death protein 1 (PD-1) and its ligand (PD-L1) may represent a key mechanism for evading immune surve
Externí odkaz:
https://doaj.org/article/a5c8c51ef27847c69ee69bbe67c23fcd
Autor:
Kanqiu Jiang, Shasha Liu, Yongbing Chen, Zhonghen Xu, Zhonghua Xu, Bo Qian, Qifeng Ding, Hongxia Cui, Yiqun Sui, Defu Cao, Weihua Xu, Mingjing Shen
Publikováno v:
Thoracic Cancer, Vol 14, Iss 27, Pp 2745-2753 (2023)
Abstract Background T cell factor‐1 (TCF‐1) + stem‐like tumor‐infiltrating lymphocytes (stem‐like TILs) are important memory cells in the tumor microenvironment. However, their relationship with clinicopathological features, CD8+ TIL densit
Externí odkaz:
https://doaj.org/article/a7dd0ba75d984864aca297faeb452034
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-11 (2022)
Abstract Sphingosine kinase 1 (SphK1) and sphingosine kinase (SphK2) are both important therapeutic targets of non-small cell lung cancer (NSCLC). SKI-349 is a novel, highly efficient and small molecular SphK1/2 dual inhibitor. Here in primary human
Externí odkaz:
https://doaj.org/article/739f3e91e8e546069af3a84394a04e69
Autor:
Kaili Ma, Lina Sun, Mingjing Shen, Xin Zhang, Zhen Xiao, Jiajia Wang, Xiaowei Liu, Kanqiu Jiang, F. Xiao-Feng Qin, Feng Guo, Baojun Zhang, Lianjun Zhang
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104347- (2022)
Summary: Exhausted CD8+ T cells with limited effector functions and high expression of multiple co-inhibitory receptors are one of the main barriers hindering antitumor immunity. The NADase CD38 has received considerable attention as a biomarker of C
Externí odkaz:
https://doaj.org/article/95851dc10bb64e0bb9cf11c80aab7481
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2019)
Abstract Adipose-derived stem cells (ASCs) are promising therapeutic cells for ischemic heart diseases, due to the ease and efficiency of acquisition, the potential of myocardial lineage differentiation, and the paracrine effects. Recently, many rese
Externí odkaz:
https://doaj.org/article/b184f54c23a44c209c1581d9bb33e32a
Autor:
Mingjing Shen, Zhonghua Xu, Weihua Xu, Kanqiu Jiang, Fuquan Zhang, Qifeng Ding, Zhonghen Xu, Yongbing Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background The cisplatin-resistance is still a main course for chemotherapy failure of lung cancer patients. Cisplatin-resistant cancer cells own higher malignance and exhibited increased metastatic ability, but the mechanism is not clear. I
Externí odkaz:
https://doaj.org/article/4516da242d8c43b1b0bb29c04c2f15e7
Autor:
LiJun Xu, XiaoDong Chen, MingJing Shen, Dong‐Rong Yang, Laifu Fang, Guobin Weng, Ying Tsai, Peter C. Keng, Yuhchyau Chen, Soo Ok Lee
Publikováno v:
Molecular Oncology, Vol 12, Iss 3, Pp 269-286 (2018)
To investigate whether IL‐6 signaling affects the susceptibility of castration‐resistant prostate cancer (CRPC) cells to cytotoxic action of natural killer (NK) cells, CRPC cell lines (having different IL‐6 levels) were developed by lentiviral
Externí odkaz:
https://doaj.org/article/0e1b38ca22934efe8f176cd3c35dcb5c
Autor:
Li Yang, MingJing Shen, Li Jun Xu, Xiaodong Yang, Ying Tsai, Peter C. Keng, Yuhchyau Chen, Soo Ok Lee
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Major progress has been made clinically in inhibiting the programmed death receptor 1 (PD-1)/PD-L1 interaction to enhance T cell-mediated immune function, yet the effectiveness of anti-PD-L1/PD-1 agents in enhancing natural killer (NK) cell
Externí odkaz:
https://doaj.org/article/c269617aaab84a4390a2877858fd746b
Publikováno v:
Tumor Biology, Vol 39 (2017)
In this study, we evaluated the prognostic potential and functional regulation of human nature antisense, brain-derived neurotrophic factor antisense, in non–small cell lung cancer. Non–small cell lung cancer carcinoma and adjacent non-carcinoma
Externí odkaz:
https://doaj.org/article/95be49b28af04dcaa4fbaf6a58db31b5
Autor:
Zhonghua Xu, Weihua Xu, Yiqun Sui, Yongbing Chen, Mingjing Shen, Hongxia Cui, Zhonghen Xu, Qifeng Ding, Youyou Wang, Kanqiu Jiang, Huan Zhang
Publikováno v:
Lung Cancer. 160:84-91
CD66b positive tumor-infiltrating neutrophils (TINs) are key immunity cells in the tumor microenvironment (TME). However, their relationship with clinicopathological features, immune checkpoints (ICs), and prognostic value remains undetermined in lun