Výsledky vyhledávání - "Minghuan Ren"

The design and synthesis of novel orally active inhibitors of AP-1 and NF-κB mediated transcriptional activation. SAR of In vitro and In vivo studies

Autor: Moorthy S. S. Palanki, Lynn J. Ransone, Minghuan Ren, Ryuichi Totsuka, Sonal Desai, Arnie Ow, Paul Erdman, Peter W. Tsao, Cheryl Spooner, Brydon L. Bennett, Mark J. Suto, Wataru Toriumi, Anthony M. Manning

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 13:4077-4080

We have developed novel orally active quinazoline analogues as inhibitors of AP-1 and NF-κB mediated transcriptional activation. Among the derivatives prepared, 1-[2-(2-thienyl)quinazolin-4-ylamino]-3-methyl-3-pyrroline-2,5-dione ( 10 ) showed signi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dea96edefc7cf5e62bc9d946524597
https://doi.org/10.1016/j.bmcl.2003.08.047

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