Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Minghai T"'
Autor:
Mengshi Hu, Tao Yang, Linyu Yang, Lu Niu, Jinbing Zhu, Ailin Zhao, Mingsong Shi, Xue Yuan, Minghai Tang, Jianhong Yang, Heying Pei, Zhuang Yang, Qiang Chen, Haoyu Ye, Ting Niu, Lijuan Chen
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/6aeb2b5162d94e52bba8affde5d0b2f5
Autor:
Qiang Qiu, Linyu yang, Yunyu Feng, Zejiang Zhu, Ning Li, Li Zheng, Yuanyuan Sun, Cong Pan, Huandi Qiu, Xue Cui, Wei He, Fang Wang, Yuyao Yi, Minghai Tang, Zhuang Yang, Yunfan Yang, Zhihui Li, Lijuan Chen, Yiguo Hu
Publikováno v:
Bioactive Materials, Vol 21, Iss , Pp 483-498 (2023)
Purinostat Mesylate (PM) is a novel highly selective and active HDAC I/IIb inhibitor, and the injectable formulation of PM (PMF) based on the compound prescription containing cyclodextrin completely can overcome PM's poor solubility and improves its
Externí odkaz:
https://doaj.org/article/0d7da28d05d149efa099f6bd699967a1
Autor:
Lu Qi, Xiangyu Pan, Xuelan Chen, Pengpeng Liu, Mei Chen, Qi Zhang, Xiaohang Hang, Minghai Tang, Dan Wen, Lunzhi Dai, Chong Chen, Yu Liu, Zhengmin Xu
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-8 (2023)
Abstract Deletions of chromosome 17p, where TP53 gene locates, are the most frequent chromosome alterations in human cancers and associated with poor outcomes in patients. Our previous work suggested that there were p53–independent mechanisms invol
Externí odkaz:
https://doaj.org/article/975f3c683e924fb88770790ccca7a190
Autor:
Zejiang Zhu, Jiaolin Wen, Yaohui Xu, Heying Pei, Dan Li, Minghai Tang, Peng Bai, Jun He, Zhuang Yang, Lijuan Chen
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 743-753 (2022)
Background: Previous studies have proven that Purinostat Mesylate (PM) is a new HDAC inhibitor and exhibits significant antitumor efficacy. However, the clinical application of PM was greatly limited by its poor solubility in water and low bioavailab
Externí odkaz:
https://doaj.org/article/79621c5371944ab3ab0dc32252cd9bfa
Autor:
Mengshi Hu, Tao Yang, Linyu Yang, Lu Niu, Jinbing Zhu, Ailin Zhao, Mingsong Shi, Xue Yuan, Minghai Tang, Jianhong Yang, Heying Pei, Zhuang Yang, Qiang Chen, Haoyu Ye, Ting Niu, Lijuan Chen
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 3, Pp 1-13 (2022)
Abstract Janus kinase 2 (JAK2) hyperactivation by JAK2 V617F mutation leads to myeloproliferative neoplasms (MPNs) and targeting JAK2 could serve as a promising therapeutic strategy for MPNs. Here, we report that Flonoltinib Maleate (FM), a selective
Externí odkaz:
https://doaj.org/article/ee4d744644724e00a080c51ba6c16a47
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1325 (2023)
Colorectal cancer (CRC) is a prevalent malignancy of the digestive tract with the second highest mortality rate globally. Piper nigrum is a widely used traditional medicinal plant, exhibiting antitumor activity against various tumor cells. At present
Externí odkaz:
https://doaj.org/article/83134278315a493085796b78d9622e42
Autor:
Jinzhu Zhang, Minghai Tang, Yujie Chen, Dan Ke, Jie Zhou, Xinyu Xu, Wenxian Yang, Jianxiong He, Haohao Dong, Yuquan Wei, James H. Naismith, Yi Lin, Xiaofeng Zhu, Wei Cheng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Steviol glycosides from the plant Stevia rebaudiana are already used as lowcalorie sweeteners, but the most abundant naturally occurring compounds have a bitter aftertaste. Here, the authors characterize and engineer rice glycosyltransferase OsUGT91C
Externí odkaz:
https://doaj.org/article/3992bcac521a4b928331e2b513baaeab
Publikováno v:
Journal of Functional Foods, Vol 98, Iss , Pp 105237- (2022)
Cancer is still considered a “hopeless case”, which seriously endangers human health. Therefore, it is of great significance to research and develop novel anticancer drugs. Active natural products play an important role in anticancer drug discove
Externí odkaz:
https://doaj.org/article/06ad03e1d83a4c2fa628e81caa6dcd32
Autor:
Jianyu Liu, Minghai Tang, Tao Li, Zhengying Su, Zejiang Zhu, Caixia Dou, Yan Liu, Heying Pei, Jianhong Yang, Haoyu Ye, Lijuan Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/62b2acb3e46243b9928d4c0135d3e767
Autor:
Rui Tao, Lin Xiao, Lifang Zhou, Zhaoyue Zheng, Jie Long, Lixing Zhou, Minghai Tang, Biao Dong, Shaohua Yao
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 95- (2022)
Externí odkaz:
https://doaj.org/article/429c85f2e6ad4614bd91c9353cf0decb