Basement membrane-related MMP14 predicts poor prognosis and response to immunotherapy in bladder cancer

Autor: Xuezhou Zhang, Baoan Hong, Hongwei Li, Jiahui Zhao, Mingchuan Li, Dechao Wei, Yongxing Wang, Ning Zhang

Publikováno v: BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)

Abstract Background Basement membrane (BM) is an important component of the extracellular matrix, which plays an important role in the growth and metastasis of tumor cells. However, few biomarkers based on BM have been developed for prognostic assess

Externí odkaz: https://doaj.org/article/51f46a545cb941d6a4c6cf2b04630229

New insights on dislocation forming mechanism of nickel-based superalloy fabricated by laser powder bed fusion

Autor: Mingchuan Li, Rui Ma, Yiqun Ren, Shuai Chang, Liqun Li

Publikováno v: Journal of Materials Research and Technology, Vol 30, Iss , Pp 4303-4309 (2024)

In this work, the forming mechanism of dislocation in laser powder bed fusion (LPBF) built IN738LC alloy was elucidated by studying the intrinsic relationships between the density and distribution of dislocation and the orientation and size of dendri

Externí odkaz: https://doaj.org/article/63d1af4cb0664c83935e68f2a2fe6de8

Development and validation of a circulating tumor cells-related signature focusing on biochemical recurrence and immunotherapy response in prostate cancer

Autor: Xuezhou Zhang, Baoan Hong, Zhipeng Sun, Jiahui Zhao, Mingchuan Li, Dechao Wei, Yongxing Wang, Ning Zhang

Publikováno v: Heliyon, Vol 9, Iss 12, Pp e22648- (2023)

Background: Studies have shown that the circulating tumor cells (CTCs) play a key role for invasion and formation of distant metastases in prostate cancer (PCa). However, few CTCs-related genes (CRGs) have been developed for biochemical recurrence (B

Externí odkaz: https://doaj.org/article/45a1bfe217b44106bbf40d3f23def6f2

Constraints on the axial-vector and pseudo-scalar mediated WIMP-nucleus interactions from PandaX-4T experiment

Autor: Zhou Huang, Chencheng Han, Abdusalam Abdukerim, Zihao Bo, Wei Chen, Xun Chen, Yunhua Chen, Chen Cheng, Zhaokan Cheng, Xiangyi Cui, Yingjie Fan, Deqing Fang, Changbo Fu, Mengting Fu, Lisheng Geng, Karl Giboni, Linhui Gu, Xuyuan Guo, Ke Han, Changda He, Jinrong He, Di Huang, Yanlin Huang, Ruquan Hou, Xiangdong Ji, Yonglin Ju, Chenxiang Li, Jiafu Li, Mingchuan Li, Shu Li, Shuaijie Li, Qing Lin, Jianglai Liu, Xiaoying Lu, Lingyin Luo, Yunyang Luo, Wenbo Ma, Yugang Ma, Yajun Mao, Yue Meng, Xuyang Ning, Ningchun Qi, Zhicheng Qian, Xiangxiang Ren, Nasir Shaheed, Changsong Shang, Xiaofeng Shang, Guofang Shen, Lin Si, Wenliang Sun, Andi Tan, Yi Tao, Anqing Wang, Meng Wang, Qiuhong Wang, Shaobo Wang, Siguang Wang, Wei Wang, Xiuli Wang, Zhou Wang, Yuehuan Wei, Mengmeng Wu, Weihao Wu, Jingkai Xia, Mengjiao Xiao, Xiang Xiao, Pengwei Xie, Binbin Yan, Xiyu Yan, Jijun Yang, Yong Yang, Chunxu Yu, Jumin Yuan, Zhe Yuan, Xinning Zeng, Dan Zhang, Minzhen Zhang, Peng Zhang, Shibo Zhang, Shu Zhang, Tao Zhang, Yingxin Zhang, Yuanyuan Zhang, Li Zhao, Qibin Zheng, Jifang Zhou, Ning Zhou, Xiaopeng Zhou, Yong Zhou, Yubo Zhou

Publikováno v: Physics Letters B, Vol 834, Iss , Pp 137487- (2022)

We present the constraints on the axial-vector and pseudo-scalar mediated WIMP-nucleus interactions from the PandaX-4T experiment, using the data set corresponding to a total exposure of 0.63 tonne⋅year. No significant signal excess is observed, an

Externí odkaz: https://doaj.org/article/29d4d3081e284b6585c5e736d5d9a1ec

Understanding Anthracycline Cardiotoxicity From Mitochondrial Aspect

Autor: Junqi Huang, Rundong Wu, Linyi Chen, Ziqiang Yang, Daoguang Yan, Mingchuan Li

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Anthracyclines, such as doxorubicin, represent one group of chemotherapy drugs with the most cardiotoxicity. Despite that anthracyclines are capable of treating assorted solid tumors and hematological malignancies, the side effect of inducing cardiac

Externí odkaz: https://doaj.org/article/a2e2c7e669fc4d6482e121de35c44f6a