Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mingchee Tan"'
Autor:
Roberto C. Andresen Eguiluz, Sierra G. Cook, Mingchee Tan, Cory N. Brown, Noah J. Pacifici, Mihir S. Samak, Lawrence J. Bonassar, David Putnam, Delphine Gourdon
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 5 (2017)
Lubricin (LUB), a major mucinous glycoprotein of mammalian synovial fluids, is believed to provide excellent lubrication to cartilage surfaces. Consequently, when joint disease or replacement leads to increased friction and surface damage in the join
Externí odkaz:
https://doaj.org/article/c92d838484044ccb8d9f34fe6f4d47da
Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening
Autor:
Amanda Chung, Rachel S. Riley, Rui Zhang, Margaret M. Billingsley, Lili Wang, Roman Spektor, Pedro P.G. Guimarães, Mingchee Tan, Rakan El-Mayta, James M. Wilson, Michael J. Mitchell
Publikováno v:
J Control Release
Messenger RNA (mRNA) has recently emerged as a promising class of nucleic acid therapy with the potential to induce protein production to treat and prevent a range of diseases. While significant progress has been made in the design of in vitro-transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8727ddebb2c77175384448c4ddf85cc6
https://doi.org/10.1016/j.jconrel.2019.10.028
https://doi.org/10.1016/j.jconrel.2019.10.028
Autor:
Roberto C. Andresen Eguiluz, David Putnam, Lawrence J. Bonassar, Kirk J. Samaroo, Delphine Gourdon, Mingchee Tan
Publikováno v:
Biotribology. 9:18-23
The glycoprotein lubricin is the primary boundary lubricant of articular cartilage. Its boundary lubricating abilities arise from two key structural features: i) a dense mucin-like domain consisting of hydrophilic oligosaccharides and ii) an end term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab0fd7adfdfb9763a415b8b413e3db67
https://doi.org/10.1016/j.biotri.2017.02.001
https://doi.org/10.1016/j.biotri.2017.02.001
Autor:
Gabriel Courties, Ribhu Nayar, David Rohde, Piotr S. Kowalski, Stephen P. Schmidt, Filip K. Swirski, Omar F. Khan, Robert Langer, Amanda Chung, Gregory R. Wojtkiewicz, Marvin Krohn-Grimberghe, Sebastian Cremer, Yoshiko Iwamoto, Yuan Sun, Vanessa Frodermann, Pedro P.G. Guimarães, Maarten Hulsmans, Daniel G. Anderson, Michael J. Mitchell, Karin Wang, Maximilian J. Schloss, Friedrich Felix Hoyer, Jamie Webster, Mingchee Tan, Matthias Nahrendorf
Publikováno v:
PMC
© 2020, The Author(s), under exclusive licence to Springer Nature Limited. Bone-marrow endothelial cells in the haematopoietic stem-cell niche form a network of blood vessels that regulates blood-cell traffic as well as the maintenance and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682398d42e04f16a5b7daa28f06b0885
https://pubmed.ncbi.nlm.nih.gov/33159192
https://pubmed.ncbi.nlm.nih.gov/33159192
Autor:
Celso Tarso Rodrigues Viana, Katherine Wu, Robert Langer, Karin Wang, Pedro P.G. Guimarães, Matthias A. Oberli, Amanda Chung, Tuomas Tammela, Michael J. Mitchell, Mingchee Tan, Tyler Jacks, Roman Spektor, Rachel S. Riley
Publikováno v:
PMC
Activation of the Wnt signaling pathway promotes lung cancer progression and contributes to poor patient prognosis. The porcupine inhibitor LGK974, a novel orally bioavailable cancer therapeutic in Phase I clinical trials, induces potent Wnt signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aca9f91916ae1feee58ca0d839adf32
https://hdl.handle.net/1721.1/126038
https://hdl.handle.net/1721.1/126038
Autor:
Delphine Gourdon, Noah J. Pacifici, Cory N. Brown, Roberto C. Andresen Eguiluz, David Putnam, Lawrence J. Bonassar, Sierra G Cook, Mingchee Tan, Mihir S. Samak
Publikováno v:
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology, Vol 5 (2017)
Frontiers in Bioengineering and Biotechnology, Vol 5 (2017)
Lubricin, a major mucinous glycoprotein of mammalian synovial fluids, is believed to provide excellent lubrication to cartilage surfaces. Consequently, when joint disease or replacement leads to increased friction and surface damage in the joint, rob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871119d5cbaf113fe7fa8606d8ab1b23
https://pubmed.ncbi.nlm.nih.gov/28702455
https://pubmed.ncbi.nlm.nih.gov/28702455
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 35(3)
The glycoprotein, lubricin, is the primary boundary lubricant of articular cartilage and has been shown to prevent cartilage damage after joint injury. In this study, a library of eight bottle-brush copolymers were synthesized to mimic the structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f68331fabe10e7d8e16043c2940e279e
https://pubmed.ncbi.nlm.nih.gov/27419808
https://pubmed.ncbi.nlm.nih.gov/27419808