Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Mingcan Xia"'
Autor:
Jing Wang, Jes S Lindholt, Galina K Sukhova, Michael A Shi, Mingcan Xia, Han Chen, Meixiang Xiang, Aina He, Yi Wang, Na Xiong, Peter Libby, Jian‐An Wang, Guo‐Ping Shi
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 7, Pp 952-969 (2014)
Abstract Immunoglobulin E (IgE) activates mast cells (MCs). It remains unknown whether IgE also activates other inflammatory cells, and contributes to the pathogenesis of abdominal aortic aneurysms (AAAs). This study demonstrates that CD4+ T cells ex
Externí odkaz:
https://doaj.org/article/42c6f3509a484046914cdb7a4ae8d78b
Autor:
Mengyang Liao, Yunzhe Wang, Junli Guo, Xian Zhang, Jingyuan Ren, Peter Libby, Karen Inouye, Gökhan S. Hotamisligil, Guanyi Lu, Guo-Ping Shi, Gilbert R. Upchurch, Mingcan Xia, Cong-Lin Liu, Marcela M. Santos, Jinying Zhang, Galina K. Sukhova, Dafeng Yang, Songyuan Luo
Publikováno v:
European Heart Journal
Aims Obesity is a risk factor of abdominal aortic aneurysm (AAA). Inflammatory cytokine interleukin-18 (IL18) has two receptors: IL18 receptor (IL18r) and Na-Cl co-transporter (NCC). In human and mouse AAA lesions, IL18 colocalizes to its receptors a
Publikováno v:
The Journal of allergy and clinical immunology. 142(4)
BACKGROUND: Exposure to traffic-related particulate matter (PM) promotes asthma and allergic diseases. However, the precise cellular and molecular mechanisms by which PM exposure acts to mediate these effects remain unclear. OBJECTIVE: We sought to e
Autor:
Michiko K. Oyoshi, Mingcan Xia, Hani Harb, Talal A. Chatila, Emmanuel Stephen Victor, Magali Noval Rivas
Publikováno v:
Journal of Allergy and Clinical Immunology. 143:AB123
Autor:
Limin Zhang, Joselyn N. Allen, Mingcan Xia, Mary J. Kennett, Shan Yu, Gayathri Balandaram, Na Xiong, Adwitia Dey, Jeffrey M. Peters, Pamela A. Hankey-Giblin, Andrew D. Patterson
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 197(1)
Obesity is a chronic inflammatory disease mediated in large part by the activation of inflammatory macrophages. This chronic inflammation underlies a whole host of diseases including atherosclerosis, hepatic steatosis, insulin resistance, type 2 diab
Autor:
Mingcan Xia, Guo-Ping Shi, Kangkang Yang, Galina K. Sukhova, Nadia Guerra, David H. Raulet, Na Xiong, Carla K. Miller
Publikováno v:
Circulation. 124:2933-2943
Background— The interplay between the immune system and abnormal metabolic conditions sustains and propagates a vicious feedback cycle of chronic inflammation and metabolic dysfunction that is critical for atherosclerotic progression. It is well es
Autor:
Yan Jin, Kavitha Narayan, David L. Wiest, Mingcan Xia, Joonsoo Kang, Yanming Wang, Christina M. Saylor, Na Xiong
Publikováno v:
The Journal of Immunology. 185:7156-7160
Various innate-like T cell subsets preferentially reside in specific epithelial tissues as the first line of defense. However, mechanisms regulating their tissue-specific development are poorly understood. Using the prototypical skin intraepithelial
Autor:
Carter R. Petty, Amparito Cunningham, Mingcan Xia, Amir Massoud, Talal A. Chatila, Peggy S. Lai, Wanda Phipatanakul
Publikováno v:
Journal of Allergy and Clinical Immunology. 141:794-796.e3
Publikováno v:
Journal of Allergy and Clinical Immunology. 141:AB283
Publikováno v:
Blood. 114:564-571
The Tec kinase Itk is critical for the development of alphabeta T cells as well as differentiation of CD4(+) T cells into Th2 cells. Itk null mice have defects in the production of Th2 cytokines; however, they paradoxically have significant elevation