Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Ming-wen Hu"'
Autor:
Mya Abousy, BA, Bani Antonio-Aguirre, MD, MPH, Kanza Aziz, MD, Ming-Wen Hu, MS, PhD, Jiang Qian, MS, PhD, Mandeep S. Singh, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 1, Pp 100327- (2024)
Objective: To cluster the diverse phenotypic features of Stargardt disease (STGD) using unsupervised clustering of multimodal retinal structure and function data. Design: Retrospective cross-sectional study. Subjects: Eyes of subjects with STGD and f
Externí odkaz:
https://doaj.org/article/6326443b2e4544328031df86666dd6d8
Autor:
Ali Reza Ahmadi, Guang Song, Tianshun Gao, Jing Ma, Xiaomei Han, Ming-Wen Hu, Andrew M Cameron, Russell N Wesson, Benjamin Philosophe, Shane Ottmann, Elizabeth King, Ahmet Gurakar, Le Qi, Brandon Peiffer, James Burdick, Robert Anders, Zhanxiang Zhou, Hongkun Lu, Dechun Feng, Chien-Sheng Chen, Jiang Qian, Bin Gao, Heng Zhu, Zhaoli Sun
Publikováno v:
eLife, Vol 12 (2023)
The pathogenesis of antibodies in severe alcoholic hepatitis (SAH) remains unknown. We analyzed immunoglobulins (Ig) in explanted livers from SAH patients (n=45) undergoing liver transplantation and tissues from corresponding healthy donors (HD, n=10
Externí odkaz:
https://doaj.org/article/91991a6ef49842e4bddb37b9334ef7f1
Autor:
Jing Zhang, Deepti Sharma, Aumreetam Dinabandhu, Jaron Sanchez, Brooks Applewhite, Kathleen Jee, Monika Deshpande, Miguel Flores-Bellver, Ming-Wen Hu, Chuanyu Guo, Shaima Salman, Yousang Hwang, Nicole M. Anders, Michelle A. Rudek, Jiang Qian, M. Valeria Canto-Soler, Gregg L. Semenza, Silvia Montaner, Akrit Sodhi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Many patients with diabetic eye disease respond inadequately to anti-VEGF therapies, implicating additional vasoactive mediators in its pathogenesis. We demonstrate that levels of angiogenic proteins regulated by HIF-1 and -2 remain elevated in the e
Externí odkaz:
https://doaj.org/article/208f02b363f54dcab967e446a3a95992
Autor:
Chi Zhang, Ming-Wen Hu, Xue-Wei Wang, Xiang Cui, Jing Liu, Qian Huang, Xu Cao, Feng-Quan Zhou, Jiang Qian, Shao-Qiu He, Yun Guan
Publikováno v:
eLife, Vol 11 (2022)
Functionally distinct subtypes/clusters of dorsal root ganglion (DRG) neurons may play different roles in nerve regeneration and pain. However, details about their transcriptomic changes under neuropathic pain conditions remain unclear. Chronic const
Externí odkaz:
https://doaj.org/article/91a1655da9c249699b25c6982e8956ac
Autor:
Sayan Ghosh, Haitao Liu, Meysam Yazdankhah, Nadezda Stepicheva, Peng Shang, Tanuja Vaidya, Stacey Hose, Urvi Gupta, Michael Joseph Calderon, Ming-Wen Hu, Archana Padmanabhan Nair, Joseph Weiss, Christopher S. Fitting, Imran A. Bhutto, Santosh Gopi Krishna Gadde, Naveen Kumar Naik, Chaitra Jaydev, Gerard A. Lutty, James T. Handa, Ashwath Jayagopal, Jiang Qian, José-Alain Sahel, Dhivyaa Rajasundaram, Yuri Sergeev, J. Samuel Zigler, Swaminathan Sethu, Simon Watkins, Arkasubhra Ghosh, Debasish Sinha
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-19 (2021)
Ghosh et al. show that a lens protein βA1-crystallin inhibits PTP1B activity, regulating the metabolism of retinal astrocytes. They find that knockdown of βA1-crystallin exacerbates the streptozotocin-induced diabetic retinopathy-like phenotype in
Externí odkaz:
https://doaj.org/article/73f2d2042a5b442cb0991f9ae494dfe7
Autor:
Srinivasa R. Sripathi, Ming-Wen Hu, Ravi Chakra Turaga, Rebekah Mikeasky, Ganesh Satyanarayana, Jie Cheng, Yukan Duan, Julien Maruotti, Karl J. Wahlin, Cynthia A. Berlinicke, Jiang Qian, Noriko Esumi, Donald J. Zack
Publikováno v:
Cells, Vol 12, Iss 8, p 1155 (2023)
Epithelial-mesenchymal transition (EMT), which is well known for its role in embryonic development, malignant transformation, and tumor progression, has also been implicated in a variety of retinal diseases, including proliferative vitreoretinopathy
Externí odkaz:
https://doaj.org/article/d5409e6c65bb44babe7141eeb0848c9b
Autor:
Xuan Cao, Jaron Castillo Sanchez, Aumreetam Dinabandhu, Chuanyu Guo, Tapan P. Patel, Zhiyong Yang, Ming-Wen Hu, Lijun Chen, Yuefan Wang, Danyal Malik, Kathleen Jee, Yassine J. Daoud, James T. Handa, Hui Zhang, Jiang Qian, Silvia Montaner, Akrit Sodhi
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 2 (2022)
Background To reduce the treatment burden for patients with neovascular age-related macular degeneration (nvAMD), emerging therapies targeting vascular endothelial growth factor (VEGF) are being designed to extend the interval between treatments, the
Externí odkaz:
https://doaj.org/article/a3a68e0a11a043ca991ca3c7280e1c9b
Autor:
Xue-Wei Wang, Shu-Guang Yang, Chi Zhang, Ming-Wen Hu, Jiang Qian, Jin-Jin Ma, Yingchi Zhang, Bin-Bin Yang, Yi-Lan Weng, Guo-Li Ming, Anish R. Kosanam, Saijilafu, Feng-Quan Zhou
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: In addition to altered gene expression, pathological cytoskeletal dynamics in the axon are another key intrinsic barrier for axon regeneration in the central nervous system (CNS). Here, we show that knocking out myosin IIA and IIB (myosin II
Externí odkaz:
https://doaj.org/article/bb0c04d931504ca59145aa66a31b03c9
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 8, p e1007040 (2019)
Single-cell RNA-sequencing (scRNA-seq) provides new opportunities to gain a mechanistic understanding of many biological processes. Current approaches for single cell clustering are often sensitive to the input parameters and have difficulty dealing
Externí odkaz:
https://doaj.org/article/d3a830bf473d41f993f0cfef169d5f55
Autor:
Ming-Wen Hu, 胡銘文
92
Magneto Hydrodynamic Theory (MHD) is a drive way based of Lorentz force in the direction perpendicular to both magnetic and electric fields. The goal of this thesis is constructing a desalination system with MHD pump by applying MHD theory. I
Magneto Hydrodynamic Theory (MHD) is a drive way based of Lorentz force in the direction perpendicular to both magnetic and electric fields. The goal of this thesis is constructing a desalination system with MHD pump by applying MHD theory. I
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/40675575563413633701