Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Ming-shi Chang"'
Autor:
Hsiao-Hsuan Wang, Wei-Yu Chen, Yi-Hsun Huang, Sheng-Min Hsu, Yeou-Ping Tsao, Yu-Hsiang Hsu, Ming-Shi Chang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-18 (2022)
Abstract Background Dry eye disease (DED) is a common disease in ophthalmology, affecting millions of people worldwide. Recent studies have shown that inflammation is the core mechanism of DED. IL-20 is a proinflammatory cytokine involved in various
Externí odkaz:
https://doaj.org/article/9cedbe4563d04603a4a4cade0da8550c
Autor:
Shao-Wei Lu, Hong-Chin Pan, Yu-Hsiang Hsu, Kung-Chao Chang, Li-Wha Wu, Wei-Yu Chen, Ming-Shi Chang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The pro-inflammatory cytokine IL-20 promotes tumor growth in several cancer types. Here, the authors show that high levels of IL-20 are associated with poor survival in patients with pancreatic ductal adenocarcinoma (PDAC) and that IL-20 blockade red
Externí odkaz:
https://doaj.org/article/daecbc35c3a24e828aa4c37a7583f7d1
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background Spinal cord injury (SCI) causes devastating neurological consequences, which can result in partial or total paralysis. Irreversible neurological deficits and glial scar formation are characteristic of SCI. Inflammatory responses a
Externí odkaz:
https://doaj.org/article/7b4e1f9c52af4a66bd65573c206fb872
Autor:
Hsiao-Hsuan Wang, Jian-Hao Huang, Min-Hao Sue, Wei-Chih Ho, Yu-Hsiang Hsu, Kung-Chao Chang, Ming-Shi Chang
Publikováno v:
EBioMedicine, Vol 64, Iss , Pp 103213- (2021)
Background: Interleukin-24 (IL-24) binds to two kinds of receptor complexes, namely IL-20R1/IL-20R2 and IL-20R2/IL-22R1, which are also bound by IL-20. IL-20 plays a detrimental role in liver fibrosis. Due to the sharing of receptor complexes, we aim
Externí odkaz:
https://doaj.org/article/dc0d72cbd28d42c3821f37cb3793da0b
Publikováno v:
Journal of Biomedical Science, Vol 25, Iss 1, Pp 1-10 (2018)
Abstract Background Millions of people around the world suffer from bone disorders, likes osteoporosis, rheumatoid arthritis (RA), and cancer-induced osteolysis. In general, the bone remodeling balance is determined by osteoclasts and osteoblasts, re
Externí odkaz:
https://doaj.org/article/ad54a03d38e64f58a988ff66844451e0
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Asthma is a chronic inflammatory disease of the airway. Its major symptoms are reversible breathing problems causing airway narrowing and obstruction. IL-19 is a member of the IL-10 family cytokines. We previously showed that IL-19 induces T-helper 2
Externí odkaz:
https://doaj.org/article/bc3b151dd74c40a58c13b4f493b8aba6
Autor:
Kun-Ling Tsai, Wan-Ching Chou, Hui-Ching Cheng, Yu-Ting Huang, Ming-Shi Chang, Shih-Hung Chan
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 275 (2021)
Acute myocardial infarction (AMI) is the most critical event in the disease spectrum of coronary artery disease. To rescue cardiomyocytes in AMI, it is important to restore blood supply as soon as possible to reduce ischemia-induced injury. However,
Externí odkaz:
https://doaj.org/article/8d6e301b6e4446d7aeec59fb6095d8f1
Autor:
Yu-Hsiang Hsu, Ya-Yu Yang, Man-Hsiang Huwang, Yun-Han Weng, I-Ming Jou, Po-Tin Wu, Tain-Yu Lin, Li-Wha Wu, Ming-Shi Chang
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175802 (2017)
Osteoarthritis (OA) is a degenerative joint disease characterized by progressive destruction of articular cartilage. Interleukin (IL)-20 is a proinflammatory cytokine involved in the pathogenesis of rheumatoid arthritis. We investigated the role of I
Externí odkaz:
https://doaj.org/article/fe0ed321c346413dae950475601e91d3
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139871 (2015)
Interleukin (IL)-20 is a proinflammatory cytokine in the IL-10 family. IL-20 is associated with tumor promotion in the pathogenesis of oral, bladder, and breast cancer. However, little is known about the role of IL-20 in prostate cancer. We hypothesi
Externí odkaz:
https://doaj.org/article/18f86b40054548f3be9c53ea1ca9f462
Autor:
Yu-Hsiang Hsu, Ming-Shi Chang
Publikováno v:
Cell Transplantation, Vol 23 (2014)
Interleukin (IL)-20, a member of the IL-10 family of cytokines, was discovered in 2001. IL-20 acts on multiple cell types by activating on a heterodimer receptor complex of either IL-20R1–IL-20R2 or IL-22R1–IL-20R2. Recent evidence indicates that
Externí odkaz:
https://doaj.org/article/bc13c25cfb4f43faa76243b7655576d4