Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ming-min Cai"'
Autor:
Fang Zhou, Jianguo Sun, Lan Yao, Ming-min Cai, Xin-yu Wang, Bin Chen, Qi-zhi Wang, Dong Feng, Guangji Wang, Jingwei Zhang, Yi-wen Zheng
Publikováno v:
Acta Pharmacologica Sinica
Etimicin (ETM), a fourth-generation aminoglycosides (AGs), is now widely clinically used in China due to its high efficacy and low toxicity. However, the mechanisms underlying its low nephrotoxicity and ototoxicity remain unclear. In the present stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364025210c55a69a50e3a23a1151da1b
https://doi.org/10.1038/s41401-019-0342-5
https://doi.org/10.1038/s41401-019-0342-5
Purpose: Pyrotinib (PTN) is primarily metabolized by cytochrome P450 (CYP)3A4 isozyme. Rifampicin (RIF) is a strong CYP3A4 inducer. Thus, the effect of oral RIF on PTN pharmacokinetics (PK) was evaluated to provide dose recommendation when co-adminis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d3ad8b13ef8a6ea031ab42865403150
https://doi.org/10.21203/rs.3.rs-1215281/v1
https://doi.org/10.21203/rs.3.rs-1215281/v1
Publikováno v:
Investigational new drugs. 40(4)
Pyrotinib (PTN), an irreversible EGFR/HER2 dual tyrosine kinase inhibitor used for treating HER2-positive breast cancer, is primarily metabolized by cytochrome P450 (CYP)3A4 isozyme. Rifampicin (RIF) is a strong index CYP3A4 inducer. Therefore, the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9c189d70cef31d226cc849b4f05038
https://pubmed.ncbi.nlm.nih.gov/35435627
https://pubmed.ncbi.nlm.nih.gov/35435627
Autor:
Ming-min Cai, Suiying Ni, Kai Zhou, Qingyun Cai, Guangji Wang, Jiali Liu, Fang Zhou, Jingwei Zhang, Lan Yao, Wenyue Liu, Qi-zhi Wang
Publikováno v:
Acta Pharmacologica Sinica. 40:556-562
Tumor vascular normalization has been proposed as a therapeutic strategy for malignant neoplasms, which can also interpret the synergistic effect of anti-angiogenesis agents combined with chemotherapy. Apatinib (Apa), a highly selective VEGFR2 inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924e6fa06dc81f29c2215765b12a0339
https://doi.org/10.1038/s41401-018-0058-y
https://doi.org/10.1038/s41401-018-0058-y
Autor:
Guangji Wang, Jianguo Sun, Fang Zhou, Xiaoliang Jin, Ying Peng, Qianying Chen, Jingwei Zhang, Ming-min Cai, Lan Yao
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 146
Etimicin (ETM), which belongs to the newest generation of aminoglycosides (AGs), has been proven to not only maintain but also strengthen the advantages of former AGs with relatively less toxicity. Now, it is widely applied for the treatment of bacte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3844c358d6e1cb1e4ed0c1a33bb7b6
https://pubmed.ncbi.nlm.nih.gov/28881316
https://pubmed.ncbi.nlm.nih.gov/28881316