Clinical value of Cyclin D1 and P21 in the differential diagnosis of papillary thyroid carcinoma

Autor: Chen-chen Wang, Dan-dan Lu, Ming-hong Shen, Ru-lei Chen, Zhi-hong Zhang, Jing-huan Lv

Publikováno v: Diagnostic Pathology, Vol 18, Iss 1, Pp 1-10 (2023)

Abstract Background With the continuous discovery of new borderline thyroid lesions and benign and malignant “gray areas”, coupled with the limitations of traditional immune indicators, the differential diagnosis of papillary thyroid carcinoma (P

Externí odkaz: https://doaj.org/article/ddfa31b7b1434739bdb71411060212f3

Assessment of Response of Kidney Tumors to Rapamycin and Atorvastatin in Tsc1+/− Mice

Autor: Ming Hong Shen, Paulina Samsel, Louise L. Shen, Kalin Narov, Jian Yang, Julian R. Sampson

Publikováno v: Translational Oncology, Vol 10, Iss 5, Pp 793-799 (2017)

Atorvastatin is widely used to lower blood cholesterol and to reduce risk of cardiovascular disease–associated complications. Epidemiological investigations and preclinical studies suggest that statins such as atorvastatin have antitumor activity f

Externí odkaz: https://doaj.org/article/d46705bbfdce49699e9d8199866c06ff

An Enhanced Tilted-Angle Acoustofluidic Chip for Cancer Cell Manipulation

Autor: Aled Clayton, Meng Cai, Xin Yang, Zhiyong Yang, Fangda Wu, Jian Yang, Chao Sun, Hanlin Wang, Xinghua Qin, Roman Mikhaylov, Jun Wei, Zhenlin Wu, Ming Hong Shen, Yong Qing Fu, Zhihua Xie, Xianfang Sun, Dongfang Liang, Fan Yuan, Liangfei Tian

In recent years, surface acoustic wave (SAW) devices have demonstrated great potentials and increasing applications in the manipulation of nano- and micro-particles including biological cells with the advantages of label-free, high sensitivity and ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583661f8d04121bfe4f420b64fb4a220
https://www.repository.cam.ac.uk/handle/1810/318259

Development and characterisation of acoustofluidic devices using detachable electrodes made from PCB

Autor: Fan Yuan, Ming Hong Shen, Hanlin Wang, Chao Sun, Zhihua Xie, Dongfang Liang, Christian Burton, Yinhua Dong, Rachel J. Errington, Zhiyong Yang, Xin Yang, Zhenlin Wu, Yong Qing Fu, Jian Yang, Despina Moschou, Marie Wiltshire, Aled Clayton, Fangda Wu, Roman Mikhaylov

Publikováno v: Mikhaylov, R, Wu, F, Wang, H, Clayton, A, Sun, C, Xie, Z, Liang, D, Dong, Y, Yuan, F, Moschou, D, Wu, Z, Shen, M H, Yang, J, Fu, Y, Yang, Z, Burton, C, Errington, R J, Wiltshire, M & Yang, X 2020, ' Development and characterisation of acoustofluidic devices using detachable electrodes made from PCB ', Lab on a Chip, vol. 20, no. 10, pp. 1807-1814 . https://doi.org/10.1039/c9lc01192g

Acoustofluidics has been increasingly applied in biology, medicine and chemistry due to its versatility in manipulating fluids, cells and nano-/micro-particles. Reducing cost and time for manufacturing surface acoustic wave (SAW)-based acoustofluidic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc4f73be6a1ff7e7d5a4ea3792aa32b

Allosteric and ATP-competitive inhibitors of mTOR effectively suppress tumor progression-associated epithelial-mesenchymal transition in the kidneys of Tsc2+/− Mice

Autor: Julian R. Sampson, Elizabeth P. Henske, Ming Hong Shen, Ashley T. Jones, Jian Yang, Kalin Narov

Publikováno v: Neoplasia (New York, N.Y.)

In tuberous sclerosis (TSC)–associated tumors, mutations in the TSC genes lead to aberrant activation of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway. mTORC1 signaling impacts many biological processes including the epit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e90b372016093f42e28d9c9ac220ff7