Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ming-hao DONG"'
Autor:
Yue Tang, Ming-Hao Dong, Xiao-Wei Pang, Hang Zhang, Yun-Hui Chu, Luo-Qi Zhou, Sheng Yang, Lu-Yang Zhang, Yun-Fan You, Li-Fang Zhu, Wei Wang, Chuan Qin, Dai-Shi Tian
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Circulating miR-30c-2-3p has been closely related to vascular diseases, however, its role and underlying mechanisms in ischemic stroke remained unclear. Our study addressed this gap by observing elevated levels of exosomal miR-30c-2-3p in pa
Externí odkaz:
https://doaj.org/article/1ef79620e5954a4292516fb148491c7b
Autor:
Lu‐Yang Zhang, Yun‐Hui Chu, Yun‐Fan You, Ming‐Hao Dong, Xiao‐Wei Pang, Lian Chen, Li‐Fang Zhu, Sheng Yang, Luo‐Qi Zhou, Ke Shang, Gang Deng, Jun Xiao, Wei Wang, Chuan Qin, Dai‐Shi Tian
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 16 (2024)
Background Stroke is a leading cause of death worldwide, with a lack of effective treatments for improving the prognosis. The aim of the present study was to identify novel therapeutic targets for functional outcome after ischemic stroke . Methods an
Externí odkaz:
https://doaj.org/article/e483fbd106114773a1a7c85bb90ee18b
Autor:
Dai-Shi Tian, Chuan Qin, Ming-Hao Dong, Michael Heming, Luo-Qi Zhou, Wen Wang, Song-Bai Cai, Yun-Fan You, Ke Shang, Jun Xiao, Di Wang, Chun-Rui Li, Min Zhang, Bi-Tao Bu, Gerd Meyer zu Hörste, Wei Wang
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 966-987 (2024)
Abstract B-cell maturation antigen (BCMA), expressed in plasmablasts and plasma cells, could serve as a promising therapeutic target for autoimmune diseases. We reported here chimeric antigen receptor (CAR) T cells targeting BCMA in two patients with
Externí odkaz:
https://doaj.org/article/bbc6bbd3f3864e94abcc50e72aa7cf93
Autor:
Sheng Yang, Chuan Qin, Man Chen, Yun‐Hui Chu, Yue Tang, Luo‐Qi Zhou, Hang Zhang, Ming‐Hao Dong, Xiao‐Wei Pang, Lian Chen, Long‐Jun Wu, Dai‐Shi Tian, Wei Wang
Publikováno v:
Advanced Science, Vol 11, Iss 10, Pp n/a-n/a (2024)
Abstract Microglia, the major resident immune cells in the central nervous system, serve as the frontline soldiers against cerebral ischemic injuries, possibly along with metabolic alterations. However, signaling pathways involved in the regulation o
Externí odkaz:
https://doaj.org/article/f6b9009f4a954c11b65cd093810c441d
Autor:
Lian Chen, Li-Fang Zhu, Lu-Yang Zhang, Yun-Hui Chu, Ming-Hao Dong, Xiao-Wei Pang, Sheng Yang, Luo-Qi Zhou, Ke Shang, Jun Xiao, Wei Wang, Chuan Qin, Dai-Shi Tian
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundGrowing evidence links immunological responses to Multiple sclerosis (MS), but specific immune factors are still unclear.MethodsMendelian randomization (MR) was performed to investigate the association between peripheral hematological trait
Externí odkaz:
https://doaj.org/article/89127e06f18348a79ec470760056cb25
Autor:
Chuan Qin, Dai-Shi Tian, Luo-Qi Zhou, Ke Shang, Liang Huang, Ming-Hao Dong, Yun-Fan You, Jun Xiao, Ying Xiong, Wen Wang, Hao Pang, Jing-Jing Guo, Song-Bai Cai, Di Wang, Chun-Rui Li, Min Zhang, Bi-Tao Bu, Wei Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Chimeric antigen receptor (CAR) T-cell therapy that targets B-cell maturation antigen (BCMA) have great potentials in autoimmune diseases and could be novel therapeutics for relapsed/refractory neuromyelitis optica spectrum disorder (NMOSD).
Externí odkaz:
https://doaj.org/article/1eb0bdae0281405d8d2cb3547cd24f23
Autor:
Chuan Qin, Sheng Yang, Man Chen, Ming-Hao Dong, Luo-Qi Zhou, Yun-Hui Chu, Zhu-Xia Shen, Dale B. Bosco, Long-Jun Wu, Dai-Shi Tian, Wei Wang
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106588- (2023)
Summary: Microglia exhibit diverse phenotypes in various central nervous system disorders and metabolic pathways exert crucial effects on microglial activation and effector functions. Here, we discovered two novel distinct microglial clusters, functi
Externí odkaz:
https://doaj.org/article/679353d10d6a4ca0a2220caa6d2d9783
Autor:
Ming-Hao Dong, Luo-Qi Zhou, Yue Tang, Man Chen, Jun Xiao, Ke Shang, Gang Deng, Chuan Qin, Dai-Shi Tian
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-9 (2022)
Abstract Background Soluble triggering receptor expressed on myeloid cells 2 (sTREM2) in cerebrospinal fluid (CSF) has been described as a biomarker for microglial activation, which were observed increased in a variety of neurological disorders. Obje
Externí odkaz:
https://doaj.org/article/050cc91d39c34ad2be8bc962d5c44ec8
Autor:
Xue ⁃ you XU, Zhen ⁃ yu YANG, Jia ⁃ quan SONG, Jian LIU, Xin XIANG, Liang ⁃zhao CHU, Yi⁃ min CHEN, Ming⁃hao DONG, Hua YANG
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 20, Iss 3, Pp 198-203 (2020)
Objective To compare the clinical efficacy and safety between endoscopic and microscopic surgery via transnasal⁃transsphenoidal approach for recurrent nonfunctional pituitary adenoma, and to explore the best way of operation. Methods The clinical d
Externí odkaz:
https://doaj.org/article/09d0d1d4d22f4988a29cc7c75fcd0dc0
Autor:
Xue-you XU, Zhen-yu YANG, Jia-quan SONG, Jian LIU, Xin XIANG, Liang-zhao CHU, Yi-min CHEN, Ming-hao DONG, Jian-mei SUI, Hua YANG
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 19, Iss 9, Pp 673-677 (2019)
Objective To investigate the effect of atorvastatin in the treatment of patients with epidual effusion after digital plastic titanium mesh cranioplasty. Methods A total of 58 patients with epidual effusion after digital plastic titanium mesh craniopl
Externí odkaz:
https://doaj.org/article/b9248c8ddf6e4c3b9d1eec146d2aa733