Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ming-Yun Chang"'
Autor:
Tien-Ying Tsai, Chun-Yu Chen, Tien-Wei Lin, Tien-Chang Lin, Feng-Lan Chiu, Orion Shih, Ming-Yun Chang, Yu-Chun Lin, An-Chung Su, Chiung-Mei Chen, U-Ser Jeng, Hung-Chih Kuo, Chi-Fon Chang, Yun-Ru Chen
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Abnormal polyglutamine (polyQ) expansion and fibrillization occur in Huntington’s disease (HD). Amyloid modifier SERF enhances amyloid formation, but the underlying mechanism is not revealed. Here, the fibrillization and toxicity effect of
Externí odkaz:
https://doaj.org/article/6e87385b553749fe86bdfe7efeea0311
Autor:
Tien-Ying Tsai, Chun-Yu Chen, Tien-Wei Lin, Tien-Chang Lin, Feng-Lan Chiu, Orion Shih, Ming-Yun Chang, Yu-Chun Lin, An-Chung Su, Chiung-Mei Chen, U-Ser Jeng, Hung-Chih Kuo, Chi-Fon Chang, Yun-Ru Chen
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/23195256cee845cba07ecc78881ccb80
Autor:
Tien-Ying Tsai, Chun-Yu Chen, Tien-Wei Lin, Tien-Chang Lin, Feng-Lan Chiu, Orion Shih, Ming-Yun Chang, Yu-Chun Lin, An-Chung Su, Chiung-Mei Chen, U-Ser Jeng, Hung-Chih Kuo, Chi-Fon Chang, Yun-Ru Chen
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/f4ca8793b2a14fec90efec80ad653915
Publikováno v:
European Journal of Medicinal Chemistry. 79:143-151
Structural optimization of the prior lead 3 led to the small molecular ( d )-leucinamides with potent modulating activity and Notch-sparing selectivity on the proteolytic processing of amyloid-β precursor proteins. The N -( R )-epoxypropyl analog 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69275d32b332651edc7f5e0b4c46918
https://doi.org/10.1016/j.ejmech.2014.04.006
https://doi.org/10.1016/j.ejmech.2014.04.006
Publikováno v:
Alzheimer's & Dementia. 15:P1296-P1296
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffa9b9a28cf4729a9f8304b3de63c337
https://doi.org/10.1016/j.jalz.2019.06.3720
https://doi.org/10.1016/j.jalz.2019.06.3720
Publikováno v:
Archiv der Pharmazie. 347:161-173
Synthesis and evaluation of difluorophenylglycinols as new modulators of proteolytic processing of the amyloid-β precursor proteins for Alzheimer's therapies were described. A range of N-substituted (R)- and (S)-difluorophenylglycinols, structured o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::173b68af31e3afd0dd889d8ffaabce3e
https://doi.org/10.1002/ardp.201300283
https://doi.org/10.1002/ardp.201300283
Retinoic acid (RA)-elicited signaling has been shown to play critical roles in development, organogenesis, and the immune response. RA regulates expression of Alzheimer’s disease (AD)-related genes and attenuates amyloid pathology in a transgenic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c08024b7b1d4d0de6d1cab96983f76
https://europepmc.org/articles/PMC3715835/
https://europepmc.org/articles/PMC3715835/
Autor:
Yu-Ching Chiou, Wen-Shan Li, Ming-Yun Chang, Shu-Chuan Jao, Yu-Ting Hsu, Wing See Lam, Wei-Jen Lo
Publikováno v:
Bioconjugate chemistry. 18(1)
A primary pathway for metabolism of electrophilic compounds in Schistosoma japonicum involves glutathione S-transferase (SjGST)-catalyzed formation of glutathione (GSH) conjugates. As part of a program aimed at gaining a better understanding of the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095fc86d04f6d144c572eb2799b6a5e5
https://pubmed.ncbi.nlm.nih.gov/17226963
https://pubmed.ncbi.nlm.nih.gov/17226963
Autor:
Wei-Jen Lo, Yu-Ching Chiou, Yu-Ting Hsu, Wing See Lam, Ming-Yun Chang, Shu-Chuan Jao, Wen-Shan Li
Publikováno v:
Bioconjugate Chemistry; Jan2007, Vol. 18 Issue 1, p109-120, 12p