Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ming-Yue Zheng"'
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87791 (2014)
Cancer, which is a leading cause of death worldwide, places a big burden on health-care system. In this study, an order-prediction model was built to predict a series of cancer drug indications based on chemical-chemical interactions. According to th
Externí odkaz:
https://doaj.org/article/0ce38ee7da274a9e9c2b301e545f283e
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56517 (2013)
Toxicity is a major contributor to high attrition rates of new chemical entities in drug discoveries. In this study, an order-classifier was built to predict a series of toxic effects based on data concerning chemical-chemical interactions under the
Externí odkaz:
https://doaj.org/article/59f7103666444374bf87f60613f96f77
Autor:
Bi-Qing Li, Bing Niu, Lei Chen, Ze-Jun Wei, Tao Huang, Min Jiang, Jing Lu, Ming-Yue Zheng, Xiang-Yin Kong, Yu-Dong Cai
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65207 (2013)
Acquired immune deficiency syndrome (AIDS) is a severe infectious disease that causes a large number of deaths every year. Traditional anti-AIDS drugs directly targeting the HIV-1 encoded enzymes including reverse transcriptase (RT), protease (PR) an
Externí odkaz:
https://doaj.org/article/f796dc65a99c4603a6af5389f0a3027c
Publikováno v:
Journal of Information Processing Systems; Feb2024, Vol. 20 Issue 1, p53-66, 14p
Autor:
Jing-Yi, Zhou, Rui-Rui, Yang, Jie, Chang, Jia, Song, Zi-Sheng, Fan, Ying-Hui, Zhang, Cheng-Hao, Lu, Hua-Liang, Jiang, Ming-Yue, Zheng, Su-Lin, Zhang
Publikováno v:
Acta Pharmacologica Sinica. 44:475-485
The B-cell lymphoma 2 (BCL-2) protein family plays a pivotal role in regulating the apoptosis process. BCL-2, as an antiapoptotic protein in this family, mediates apoptosis resistance and is an ideal target for cell death strategies in cancer therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adaf22499c4e65de6b1abc755d2c9fec
https://doi.org/10.1038/s41401-022-00936-0
https://doi.org/10.1038/s41401-022-00936-0
Autor:
Lan-song Xu, Su-xin Zheng, Liang-he Mei, Ke-xin Yang, Ya-fang Wang, Qiang Zhou, Xiang-tai Kong, Ming-yue Zheng, Hua-liang Jiang, Cheng-ying Xie
Publikováno v:
Acta Pharmacologica Sinica.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76869105186e3600c11dada1296b9dc6
https://doi.org/10.1038/s41401-023-01053-2
https://doi.org/10.1038/s41401-023-01053-2
Autor:
Jia Song, Rui-rui Yang, Jie Chang, Ya-dan Liu, Cheng-hao Lu, Li-fan Chen, Hao Guo, Ying-hui Zhang, Zi-sheng Fan, Jing-yi Zhou, Gui-zhen Zhou, Ke-ke Zhang, Xiao-min Luo, Kai-xian Chen, Hua-liang Jiang, Su-lin Zhang, Ming-yue Zheng
Publikováno v:
Acta pharmacologica Sinica.
Cyclic GMP-AMP synthase (cGAS), a cytosolic DNA sensor, acts as a nucleotidyl transferase that catalyzes ATP and GTP to form cyclic GMP-AMP (cGAMP) and plays a critical role in innate immunity. Hyperactivation of cGAS-STING signaling contributes to h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0ff544a594b503f89e956a5e12b1c7
https://pubmed.ncbi.nlm.nih.gov/36229599
https://pubmed.ncbi.nlm.nih.gov/36229599
Publikováno v:
Journal of chromatography. A. 1625
The long identified toxic gas, hydrogen sulfide (H2S), which has also been confirmed as the third gaseous signaling molecule following NO and CO, plays important roles in various physiological and pathological process. The current most established qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c7ec87558346392513a9b911d18df5
https://pubmed.ncbi.nlm.nih.gov/32709315
https://pubmed.ncbi.nlm.nih.gov/32709315
Publikováno v:
Oral Diseases. 22:688-696
OBJECTIVE To evaluate the antitumor effects of fusion protein hGrB-TV of human granzyme B (hGrB) and truncated vascular endothelial growth factor (tVEGF) on human oral squamous cell carcinoma (OSCC) in vitro and in vivo. METHODS The fusion protein hG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442d26d7663cdd9e72930db8ca11485a
https://doi.org/10.1111/odi.12522
https://doi.org/10.1111/odi.12522
Publikováno v:
Procedia Computer Science. 92:536-542
The high penetration of renewable energy sources in power systems will deteriorate power quality and affect frequency stability. This issue is more severe in a small-capacity area or island power system that is weakly linked to the main grid. For the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15b9f25be71140b0f00d75dad167670