Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ming-Tian Che"'
Autor:
Hui Jin, Yu-Ting Zhang, Yang Yang, Lan-Yu Wen, Jun-Hua Wang, Hao-Yu Xu, Bi-Qin Lai, Bo Feng, Ming-Tian Che, Xue-Cheng Qiu, Zhi-Ling Li, Lai-Jian Wang, Jing-Wen Ruan, Bin Jiang, Xiang Zeng, Qing-Wen Deng, Ge Li, Ying Ding, Yuan-Shan Zeng
Publikováno v:
Stem Cell Reports, Vol 12, Iss 2, Pp 274-289 (2019)
Summary: The hostile environment of an injured spinal cord makes it challenging to achieve higher viability in a grafted tissue-engineered neural network used to reconstruct the spinal cord circuit. Here, we investigate whether cell survival and syna
Externí odkaz:
https://doaj.org/article/53633a003e924f82864f286d0c0740e2
Autor:
Bi‐Qin Lai, Ming‐Tian Che, Bo Feng, Yu‐Rong Bai, Ge Li, Yuan‐Huan Ma, Lai‐Jian Wang, Meng‐Yao Huang, Ya‐Qiong Wang, Bin Jiang, Ying Ding, Xiang Zeng, Yuan‐Shan Zeng
Publikováno v:
Advanced Science, Vol 6, Iss 22, Pp n/a-n/a (2019)
Abstract Tissue engineering produces constructs with defined functions for the targeted treatment of damaged tissue. A complete spinal cord injury (SCI) model is generated in canines to test whether in vitro constructed neural network (NN) tissues ca
Externí odkaz:
https://doaj.org/article/fc9e523a3a044db99e36de113137000c
Autor:
Xin-Yi Lin, Bi-Qin Lai, Xiang Zeng, Ming-Tian Che, Eng-Ang Ling, Wutian Wu, Yuan-Shan Zeng M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Spinal cord injury (SCI) can cause severe traumatic injury to the central nervous system (CNS). Current therapeutic effects achieved for SCI in clinical medicine show that there is still a long way to go to reach the desired goal of full or significa
Externí odkaz:
https://doaj.org/article/6c11f852d8274ed28546fbacc44ca3d2
Autor:
Hui-Yong Shen, Ge Li, Xiang Zeng, Xue-Cheng Qiu, Ming-Tian Che, Bo Feng, Yuan-Shan Zeng, Bi-Qin Lai, Eng-Ang Ling
Publikováno v:
Journal of Biomedical Materials Research Part A. 106:2158-2170
Spinal cord injury (SCI) normally results in cell death, scarring, cavitation, inhibitory molecules release, etc., which are regarded as a huge obstacle to reconnect the injured neuronal circuits because of the lack of effective stimulus. In this stu
Autor:
Ying Ding, Yuan-Shan Zeng, Zaid Aljuboori, Limin Rong, Ming-Tian Che, Mao Pang, Qing-Shuai Wei, Zhou Liu, Inbo Han, Xiang Zeng, Guo-Hui Wu, Eng-Ang Ling, Xue-Cheng Qiu, Jia-Hui Sun, Yuan-Huan Ma, Bin Liu
Publikováno v:
Biomaterials. 160:37-55
The functional multipotency enables mesenchymal stem cells (MSCs) promising translational potentials in treating spinal cord injury (SCI). Yet the fate of MSCs grafted into the injured spinal cord has not been fully elucidated even in preclinical stu
Publikováno v:
Biomaterials. 279:121211
The inability of adult mammals to recover function lost after severe spinal cord injury (SCI) has been known for millennia and is mainly attributed to a failure of brain-derived nerve fiber regeneration across the lesion. Potential approaches to re-e
Autor:
Yuan-Huan Ma, Shu Liu, Yuan-Shan Zeng, Xiang Zeng, Ke Zhang, Bao-Ling Du, Jin-Lang Wu, Bo Feng, Ming-Tian Che, Huiyong Shen, Bi-Qin Lai, Xue-Chen Qiu, Eng-Ang Ling
Publikováno v:
Biomaterials. 109:40-54
Severe spinal cord injury (SCI) causes loss of neural connectivity and permanent functional deficits. Re-establishment of new neuronal relay circuits after SCI is therefore of paramount importance. The present study tested our hypothesis if co-cultur
Autor:
Ya-Qiong Wang, Bin Jiang, Bi-Qin Lai, Bo Feng, Yu-Rong Bai, Xiang Zeng, Yuan-Huan Ma, Yuan-Shan Zeng, Meng-Yao Huang, Ying Ding, Ming-Tian Che, Ge Li, Lai-Jian Wang
Publikováno v:
Advanced Science
Advanced Science, Vol 6, Iss 22, Pp n/a-n/a (2019)
Advanced Science, Vol 6, Iss 22, Pp n/a-n/a (2019)
Tissue engineering produces constructs with defined functions for the targeted treatment of damaged tissue. A complete spinal cord injury (SCI) model is generated in canines to test whether in vitro constructed neural network (NN) tissues can relay t
Autor:
Ge Li, Ming-Tian Che, Si-Mei Long, Shu Liu, Rui-Qiang Chen, Jin-Lang Wu, Ke Zhang, Yuan-Shan Zeng, Huiyong Shen, Li-Na Qin, Eng-Ang Ling, Yu-Ting Zhang, Limin Rong, Ying Ding
Publikováno v:
Biomaterials. 83:233-248
Persistent neurotrophic factor delivery is crucial to create a microenvironment for cell survival and nerve regeneration in spinal cord injury (SCI). This study aimed to develop a NT-3/fibroin coated gelatin sponge scaffold (NF-GS) as a novel control
Autor:
Hao-Yu Xu, Bo Feng, Xiang Zeng, Jing-Wen Ruan, Yu-Ting Zhang, Ying Ding, Bin Jiang, Lai-Jian Wang, Hui Jin, Jun-Hua Wang, Yuan-Shan Zeng, Lan-Yu Wen, Ming-Tian Che, Qing-Wen Deng, Bi-Qin Lai, Yang Yang, Ge Li, Xue-Cheng Qiu, Zhi-Ling Li
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 12, Iss 2, Pp 274-289 (2019)
Stem Cell Reports, Vol 12, Iss 2, Pp 274-289 (2019)
Summary The hostile environment of an injured spinal cord makes it challenging to achieve higher viability in a grafted tissue-engineered neural network used to reconstruct the spinal cord circuit. Here, we investigate whether cell survival and synap