Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Ming-T. Lin"'
Autor:
Jiunn Jong Wu, Ming T. Lin, Yuh Ling Chen, Yee Shin Lin, Jun Neng Roan, Pao Yen Lin, Tak Wah Wong, Yueh Hsia Luo, Ching Chuan Liu, Woei Jer Chuang
Publikováno v:
Laboratory Investigation. 90:1492-1506
Molecular mimicry between group A streptococcus and host antigens has important roles in the development of post-streptococcal sequelae, including glomerulonephritis and rheumatic heart disease (RHD). The etiology of RHD involves host cross-reactivit
Autor:
Jiunn Jong Wu, Ming-T. Lin, Chia-Wen Chang, Yee Shin Lin, Pei Jane Tsai, Woei Jer Chuang, Siang-Yu Wu, Ching Chuan Liu
Publikováno v:
Experimental Biology and Medicine. 234:1316-1326
We have previously identified αvβ3and Fas as receptors for the streptococcal pyrogenic exotoxin B (SPE B), and G308S, a mutant of SPE B with RSD motif, which interacts with Fas only. This study aims to evaluate how SPE B interacts with cells to ind
Autor:
Ching Chuan Liu, Pei Jane Tsai, Wan Hua Tsai, Jiunn Jong Wu, Yee Shin Lin, Woei Jer Chuang, Ming T. Lin, Chia Wen Chang
Publikováno v:
Journal of Biological Chemistry. 284:33195-33205
We have previously identified integrin alpha(v)beta(3) and Fas as receptors for the streptococcal pyrogenic exotoxin B (SPE B), and G308S, a mutant of SPE B that binds to Fas only. In the current study we found that after binding to alpha(v)beta(3),
Autor:
Jiunn Jong Wu, Po Xing Zheng, Chuan Chiang-Ni, Ming T. Lin, Woei Jer Chuang, Yueh Ren Ho, Ching Chuan Liu, Hsiu Mei Wu, Yee Shin Lin
Publikováno v:
Journal of Clinical Microbiology. 47:3161-3169
Streptococcus pyogenes (group A streptococcus [GAS]) is a versatile human pathogen, and emm1 /sequence type 28 (ST28) is the most frequently isolated type from GAS infections. The emm1 /ST28 strain is associated with necrotizing fasciitis and strepto
Autor:
Jiunn Jong Wu, Chih Feng Kuo, Wenya Huang, Pei Ju Wang, Woei Jer Chuang, Hsiang Chee Houng, Ching Chuan Liu, Ming T. Lin, Chun-Liang Chen, Yee Shin Lin, Chih Chieh Wang
Publikováno v:
Journal of Biological Chemistry. 284:10957-10967
Streptococcal pyrogenic exotoxin B (SPE B) is a cysteine protease expressed by Streptococcus pyogenes. The D9N, G163S, G163S/A172S, and G239D mutant proteins were expressed to study the effect of the allelic variants on their protease activity. In co
Autor:
Chuan Chiang-Ni, Chih Cheng Tsou, Yee Shin Lin, Ming T. Lin, Jiunn Jong Wu, Ching Chuan Liu, Woei Jer Chuang
Publikováno v:
Gene. 427:99-103
CovR/S is an important two component regulatory system, which regulates about 15% of the gene expression in Streptococcus pyogenes. The covR/S locus was identified as an operon generating an RNA transcript around 2.5-kb in size. In this study, we fou
Autor:
Wei Lun Tsai, Ching Chuan Liu, Ju Fei Hsu, Yi Hsuan Hsieh, Shu Chu Shiesh, Woei Jer Chuang, Tzu N. Fu, Yu Jun Huang, Ming T. Lin, Yee Shin Lin, Jui He Tsai, Chih Chieh Wang, Wenya Huang, Jiunn Jong Wu
Publikováno v:
The Journal of Infectious Diseases. 198:367-374
Group A Streptococcus is a common pathogen that causes pharyngitis, impetigo, myositis, and lethal streptococcal toxic shock syndrome. Streptococcal pyrogenic exotoxin B (SPE B) is strongly associated with the severity of disease. SPE B is a cysteine
Autor:
Wan Hua Tsai, Jiunn Jong Wu, Woei Jer Chuang, Pei Jane Tsai, Ming T. Lin, Yee Shin Lin, Ching Chuan Liu, Chia Wen Chang
Publikováno v:
Infection and Immunity. 76:1349-1357
Our previous work suggested that streptococcal pyrogenic exotoxin (SPE) B-induced apoptosis is mediated through a receptor-like mechanism. In this study, we have identified α v β 3 and Fas as the SPE B receptors for this function. The SPE B fragmen
Autor:
Ming T. Lin, Vasily1, Wen-Chi Su, Vasily1, Mei-Ling Cheng, Vasily1, Kwang-Shien Cheng, Vasily1, Wen-Chang Chang2, Lih-Yuh C. Wing, Vasily3, Chauyin J. Jen, Vasily3, Hua-Lin Wu, Vasily1
Publikováno v:
Journal of Biomedical Science. 1999, Vol. 6 Issue 4, p260-268. 9p. 1 Chart, 6 Graphs.
Autor:
Ching Chuan Liu, Pei Jane Tsai, Ming T. Lin, Wan Hua Tsai, Woei Jer Chuang, Chia Wen Chang, Yee Shin Lin, Jiunn Jong Wu
Publikováno v:
Journal of Biomedical Science. 14:419-427
After streptococcal pyrogenic exotoxin B (SPE B) induces apoptosis, its fate is unknown. Using confocal time-course microscopy at 37 degrees C, we detected green fluorescence 20 min after adding FITC-SPE B. Orange fluorescence, an indication of co-lo