Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Ming-Ming Wu"'
Autor:
Ming‐Ming Wu, Yan‐Chao Yang, Yong‐Xu Cai, Shuai Jiang, Han Xiao, Chang Miao, Xi‐Yun Jin, Yu Sun, Xin Bi, Zi Hong, Di Zhu, Miao Yu, Jian‐Jun Mao, Chang‐Jiang Yu, Chen Liang, Liang‐Liang Tang, Qiu‐Shi Wang, Qun Shao, Qing‐Hua Jiang, Zhen‐Wei Pan, Zhi‐Ren Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract The risk for suffering immune checkpoint inhibitors (ICIs)‐associated myocarditis increases in patients with pre‐existing conditions and the mechanisms remain to be clarified. Spatial transcriptomics, single‐cell RNA sequencing, and fl
Externí odkaz:
https://doaj.org/article/f762988008d54502959e5c209199f42f
Autor:
Liang-Liang Tang, Xu Yang, Shu-Qi Yu, Qi Qin, Rong Xue, Yu Sun, Han Xiao, An-Qi Shang, Jia-Qun Liu, Song-Qi Han, Chen Liang, Jie Lou, Qiu-Shi Wang, Chang-Jiang Yu, Ming-Ming Wu, Zhi-Ren Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Previous studies have demonstrated that activated endothelial epithelial sodium channel (EnNaC) impairs vasodilatation, which contributes to salt-sensitive hypertension. Here, we investigate whether mesenteric artery (MA) EnNaC is involve
Externí odkaz:
https://doaj.org/article/50b83b65f87e48d3b4da752385de261d
Autor:
Chen Liang, Qiu-Shi Wang, Xu Yang, Di Zhu, Yu Sun, Na Niu, Jie Yao, Bi-Han Dong, Shuai Jiang, Liang-Liang Tang, Jie Lou, Chang-Jiang Yu, Qun Shao, Ming-Ming Wu, Zhi-Ren Zhang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
BackgroundHyperhomocysteinemia (HHcy) causes cardiovascular diseases via regulating inflammatory responses. We investigated whether and how the epithelial sodium channel (ENaC), a recently identified ion channel in endothelial cells, plays a role in
Externí odkaz:
https://doaj.org/article/b3379b58c6a74932ba3112b43f65a8f2
Autor:
Yong-Xu Cai, Bao-Long Zhang, Miao Yu, Yan-Chao Yang, Xue Ao, Di Zhu, Qiu-Shi Wang, Jie Lou, Chen Liang, Liang-Liang Tang, Ming-Ming Wu, Zhi-Ren Zhang, He-Ping Ma
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
We have shown that cholesterol regulates the activity of ion channels in mouse cortical collecting duct (CCD) mpkCCDc14 cells and that the transient receptor potential melastatin 4 (TRPM4) channel is expressed in these cells. However, whether TRPM4 c
Externí odkaz:
https://doaj.org/article/a488d6fafc37435190f74649a7756374
Autor:
Qiu-Shi Wang, Chen Liang, Shuai Jiang, Di Zhu, Yu Sun, Na Niu, Xu Yang, Yan-Chao Yang, Bi-Han Dong, Jie Yao, Chang-Jiang Yu, Jie Lou, Liang-Liang Tang, Ming-Ming Wu, Zhi-Ren Zhang, He-Ping Ma
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The use of cyclosporine A (CsA) in transplant recipients is limited due to its side effects of causing severe hypertension. We have previously shown that CsA increases the activity of the epithelial sodium channel (ENaC) in cultured distal nephron ce
Externí odkaz:
https://doaj.org/article/aa9bcbbf23bd4489a7bc642cfc0eafd9
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Antiangiogenic tyrosine kinases inhibitors induce hypertension, which may increase the incidents of cardiovascular complications and limit their use. However, the mechanisms by which usage of TKIs results in hypertension have not been fully understoo
Externí odkaz:
https://doaj.org/article/dd014d3508f84cdb826ad3a9217a62f6
Autor:
Yu-Jia Zhai, Bing-Chen Liu, Shi-Peng Wei, Chu-Fang Chou, Ming-Ming Wu, Bin-Lin Song, Valerie A. Linck, Li Zou, Shuai Zhang, Xue-Qi Li, Zhi-Ren Zhang, He-Ping Ma
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 3, Pp 1051-1059 (2018)
Background/Aims: The epithelial sodium channel (ENaC) in cortical collecting duct (CCD) principal cells plays a critical role in regulating systemic blood pressure. We have previously shown that cholesterol (Cho) in the apical cell membrane regulates
Externí odkaz:
https://doaj.org/article/dfaf7a60b0324aaab53855043374ac19
Autor:
Xiao Han, Zhi-Ren Zhang, Xiao Yan, Qiu-Shi Wang, Chen Liang, Zhi-Chao Dong, Ming-Ming Wu, Yun-Long Zhang, Lei-Xin Zou, Chen Chen, Bo Zhang
Publikováno v:
Acta Pharmacol Sin
Aflibercept, as a soluble decoy vascular endothelial growth factor receptor, Which has been used as a first-line monotherapy for cancers. Aflibercept often causes cardiovascular toxicities including hypertension, but the mechanisms underlying afliber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1603d98a5ad4f517c7fe4da9c4868ad1
https://doi.org/10.1038/s41401-020-00569-1
https://doi.org/10.1038/s41401-020-00569-1
Autor:
Chen, Liang, Di, Zhu, Wei, Xia, Zi, Hong, Qiu-Shi, Wang, Yu, Sun, Yan-Chao, Yang, Song-Qi, Han, Liang-Liang, Tang, Jie, Lou, Ming-Ming, Wu, Zhi-Ren, Zhang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1869:166586
Lenvatinib, a multitarget tyrosine kinase inhibitor (TKI), increases the incidence of severe hypertension and thus the incidence of cardiovascular complications. Inhibition of ferroptosis, a newly recognized type of cell death, alleviates endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb410cbec23ecfae65c8d9c5a3459bae
https://doi.org/10.1016/j.bbadis.2022.166586
https://doi.org/10.1016/j.bbadis.2022.166586
Autor:
Qiu-Shi Wang, Xu Yang, Chen Liang, Di Zhu, Jie Lou, Na Niu, Qun Shao, Liang-Liang Tang, Zhi-Ren Zhang, Shuai Jiang, Bi-Han Dong, Ming-Ming Wu, Jie Yao, Yu Sun, Chang-Jiang Yu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
BackgroundHyperhomocysteinemia (HHcy) causes cardiovascular diseases via regulating inflammatory responses. We investigated whether and how the epithelial sodium channel (ENaC), a recently identified ion channel in endothelial cells, plays a role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b47b7c7fc7d4f5069311bf38fa0b88a
https://www.frontiersin.org/articles/10.3389/fcell.2021.672335/full
https://www.frontiersin.org/articles/10.3389/fcell.2021.672335/full