Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ming-Kuei Jang"'
Autor:
Chi-Chang Weng, Ing-Tsung Hsiao, Qing-Fang Yang, Cheng-Hsiang Yao, Chin-Yin Tai, Meng-Fang Wu, Tzu-Chen Yen, Ming-Kuei Jang, Kun-Ju Lin
Publikováno v:
Molecules, Vol 25, Iss 7, p 1750 (2020)
Misfolding, aggregation, and cerebral accumulation of tau deposits are hallmark features of Alzheimer’s disease. Positron emission tomography study of tau can facilitate the development of anti-tau treatment. Here, we investigated a novel tau trace
Externí odkaz:
https://doaj.org/article/c7bf3fa6485943b29f56f0440e07552f
Autor:
Tabassum Majid, Yousuf O. Ali, Deepa V. Venkitaramani, Ming-Kuei Jang, Hui-Chen Lu, Robia G. Pautler
Publikováno v:
NeuroImage: Clinical, Vol 4, Iss C, Pp 711-717 (2014)
Background: Axonal transport is vital for neurons and deficits in this process have been previously reported in a few mouse models of Alzheimer's disease prior to the appearance of plaques and tangles. However, it remains to be determined whether axo
Externí odkaz:
https://doaj.org/article/cdaf9916cbab47f7b9bcb2c8c94459c0
Autor:
Masaomi Miyamoto, Chio Okuyama, Shinya Kagawa, Kuninori Kusano, Masaaki Takahashi, Keisuke Takahata, Ming-Kuei Jang, Hiroshi Yamauchi
Publikováno v:
Annals of Nuclear Medicine. 37:300-309
Objective Abnormal aggregation of tau in the brain is a major contributing factor in various neurodegenerative diseases. Florzolotau (18F) (florzolotau, APN-1607, PM-PBB3) has been shown to be a probe for tau fibrils in an animal model and patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e52d239e48544fd12c768e505fc1b577
https://doi.org/10.1007/s12149-023-01828-x
https://doi.org/10.1007/s12149-023-01828-x
Autor:
Paul Tempest, Yih‐Shyan Lin, Chin‐Yin Tai, Maiko Ono, David S Russell, Christine M Sandiego, Vincent Carroll, Roger N Gunn, Richard A Margolin, Makoto Higuchi, Ming‐Kuei Jang
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c24ac7d8f3fe8567417ecf384c099b36
https://doi.org/10.1002/alz.063028
https://doi.org/10.1002/alz.063028
Autor:
Paul Tempest, Yih‐Shyan Lin, Yen‐Ting Lai, Chin‐Yin Tai, Haou‐Tzong Ma, Sheng‐Chieh Huang, Richard A Margolin, Chia‐Lin Wu, Ming‐Kuei Jang
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8fbd268cc071ab9b686054a8aa2c959
https://doi.org/10.1002/alz.062995
https://doi.org/10.1002/alz.062995
Autor:
Paul Tempest, Chin‐Yin Tai, Maiko Ono, Marc B Skaddan, Kyle C Wilcox, Aimee Reed, Srirajan Vaidyanathan, Claus T Christoffersen, Pekka Kallunki, Benny Bang‐Andersen, Richard A Margolin, Tzu‐Huei Kao, Makoto Higuchi, Ming‐Kuei Jang
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dbbb2082a98dc64a4c481983ad9cd7c
https://doi.org/10.1002/alz.063036
https://doi.org/10.1002/alz.063036
Autor:
Yihui Guan, Jiaying Lu, Progressive Supranuclear Palsy Neuroimage Initiative, Qi-Si Chen, Weiqi Bao, Xin-Yi Li, Ling Li, Ming-Kuei Jang, Xin-Yue Zhou, Ming Li, Chuantao Zuo, Jian-Jun Wu, Xiaoniu Liang, Tzu-Chen Yen, Jian-Feng Luo, Feng-Tao Liu, Jian Wang, Yi-Min Sun
Publikováno v:
Movement Disorders. 36:2314-2323
Background 18 F-APN-1607 is a novel tau PET tracer characterized by high binding affinity for 3- and 4-repeat tau deposits. Whether 18 F-APN-1607 PET imaging is clinically useful in PSP remains unclear. Objectives The objective of this study was to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3929a493d4024ec57e8d2c4bb30cb124
https://doi.org/10.1002/mds.28672
https://doi.org/10.1002/mds.28672
Autor:
Shi, Yang, G Murzin, Alexey, Falcon, Benjamin, Epstein, Alexander, Machin, Jonathan, Tempest, Paul, L Newell, Kathy, Vidal, Ruben, J Garringer, Holly, Sahara, Naruhiko, Higuchi, Makoto, Ghetti, Bernardino, Ming-Kuei, Jang, H W Scheres, Sjors, Goedert, Michel, Naruhiko, Sahara, Makoto, Higuchi
Publikováno v:
Acta neuropathologica. 141:697-708
Tau and Aβ assemblies of Alzheimer's disease (AD) can be visualized in living subjects using positron emission tomography (PET). Tau assemblies comprise paired helical and straight filaments (PHFs and SFs). APN-1607 (PM-PBB3) is a recently described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::397a0ac7e1fbf65b3f38f583242b6a7a
https://repo.qst.go.jp/records/82299
https://repo.qst.go.jp/records/82299
Autor:
Hwan-Ching Tai, Haou-Tzong Ma, Shien-Chieh Huang, Meng-Fang Wu, Chia-Lin Wu, Yen-Ting Lai, Zhong-Lin Li, Richard Margolin, Anthony J. Intorcia, Geidy E. Serrano, Thomas G. Beach, Madhaven Nallani, Bradford Navia, Ming-Kuei Jang, Chin-Yin Tai
Numerous tau immunotherapies are being developed against Alzheimer’s disease (AD), but it has been challenging to specifically target early-stage tau aggregates using conformation-dependent antibodies. Here, we report a monoclonal antibody, APNmAb0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28034efadcf6cbf1c842c67300ea321c
https://doi.org/10.1101/2022.06.24.497452
https://doi.org/10.1101/2022.06.24.497452
Autor:
Yi-Ching Weng, Jung-Lung Hsu, Ming-Kuei Jang, Tzu-Chen Yen, Chiung-Chih Chang, Hsiu-Chuan Wu, Kun-Ju Lin, Kuo-Lun Huang, Chi-Hung Liu, Chu-Yun Huang, Ing-Tsung Hsiao, Makoto Higuchi, Chin-Chang Huang
Publikováno v:
Clinical Nuclear Medicine. 45:747-756
PURPOSE OF THE REPORT In vivo tau PET imaging could help clarify the spatial distribution of tau deposition in Alzheimer disease (AD) and aid in the differential diagnosis of tauopathies. To date, there have been no in vivo F-APN1607 tau PET studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2846d69280bd922689cc94d697b93c33
https://doi.org/10.1097/rlu.0000000000003164
https://doi.org/10.1097/rlu.0000000000003164