Multivalent mRNA Vaccine Elicits Broad Protection against SARS-CoV-2 Variants of Concern

Autor: Monika Kumari, Kang-Hao Liang, Shih-Chieh Su, Hsiu-Ting Lin, Yu-Feng Lu, Ming-Jane Wu, Wan-Yu Chen, Han-Chung Wu

Publikováno v: Vaccines, Vol 12, Iss 7, p 714 (2024)

SARS-CoV-2 new waves are primarily caused by changes to the spike protein (S), which can substantially decrease the efficacy of vaccines. Therefore, we tested several multivalent mRNA-LNP vaccines, targeting the full-length S proteins of different va

Externí odkaz: https://doaj.org/article/065a807d43ca4f63bb9b8eec1855c9e7

5-HT7 Receptor Inhibition Transiently Improves Respiratory Function Following Daily Acute Intermittent Hypercapnic-Hypoxia in Rats With Chronic Midcervical Spinal Cord Contusion

Autor: Ming-Jane Wu, Kun-Ze Lee, Chun-Lin Chen, Stéphane Vinit

Publikováno v: Neurorehabilitation and Neural Repair
Neurorehabilitation and Neural Repair, SAGE Publications (UK and US), 2020, 34 (4), pp.333-343. ⟨10.1177/1545968320905806⟩

Background. Intermittent hypoxia can induce respiratory neuroplasticity to enhance respiratory motor outputs following hypoxic treatment. This type of respiratory neuroplasticity is primarily mediated by the activation of Gq-protein-coupled 5-HT2 rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b900ba273979cb08784a0ae334ed05b
https://pubmed.ncbi.nlm.nih.gov/32102596

Modulation of Serotonin and Adenosine 2A Receptors on Intermittent Hypoxia-Induced Respiratory Recovery following Mid-Cervical Contusion in the Rat

Autor: Ming-Jane Wu, Kun-Ze Lee, Stéphane Vinit, Ming-Han Wen

Publikováno v: Journal of neurotrauma. 36(21)

The present study was designed to evaluate the therapeutic effectiveness and mechanism of acute intermittent hypoxia on respiratory function at distinct injury stages following mid-cervical spinal contusion. In the first experiment, adult male rats r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b957b293aed5e00eb2568133b4e72531
https://pubmed.ncbi.nlm.nih.gov/31099299