Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Ming-Hu Han"'
Autor:
Yi Han, Lin Ai, Lingzhen Song, Yu Zhou, Dandan Chen, Sha Sha, Ran Ji, Qize Li, Qingyang Bu, Xiangyu Pan, Xiaojing Zhai, Mengqiao Cui, Jiawen Duan, Junxia Yang, Dipesh Chaudhury, Ankang Hu, He Liu, Ming-Hu Han, Jun-Li Cao, Hongxing Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The potential brain mechanism underlying resilience to socially transferred allodynia remains unknown. Here, we utilize a well-established socially transferred allodynia paradigm to segregate male mice into pain-susceptible and pain-resilien
Externí odkaz:
https://doaj.org/article/5e29d2a303854ab692253dc0a0ccda0e
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3875 (2024)
The midbrain dopamine system is a sophisticated hub that integrates diverse inputs to control multiple physiological functions, including locomotion, motivation, cognition, reward, as well as maternal and reproductive behaviors. Dopamine is a neurotr
Externí odkaz:
https://doaj.org/article/48da73624ca6415db452a06bbdc400b0
Autor:
Min Cai, Yingbo Zhu, Mary Regis Shanley, Carole Morel, Stacy M. Ku, Hongxing Zhang, Yuan Shen, Allyson K. Friedman, Ming-Hu Han
Publikováno v:
Neurobiology of Stress, Vol 26, Iss , Pp 100565- (2023)
Repeated, long-term (weeks to months) exposure to standard antidepressant medications is required to achieve treatment efficacy. In contrast, acute ketamine quickly improves mood for an extended time. Recent work implicates that hyperpolarization-act
Externí odkaz:
https://doaj.org/article/2ead91ec8e4545f393f903b88152f259
Autor:
Hualong Wang, Guiqin Chen, Eun Hee Ahn, Yiyuan Xia, Seong Su Kang, Xia Liu, Chang Liu, Ming-Hu Han, Shengdi Chen, Keqiang Ye
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Parkinson’s disease (PD) is the most common neurodegenerative motor disorder, and its pathologic hallmarks include extensive dopaminergic neuronal degeneration in the Substantia nigra associated with Lewy bodies, predominantly consisting o
Externí odkaz:
https://doaj.org/article/e6b4b28683c344a0b073d73e4544a94e
Autor:
Carole Morel, Sarah E. Montgomery, Long Li, Romain Durand-de Cuttoli, Emily M. Teichman, Barbara Juarez, Nikos Tzavaras, Stacy M. Ku, Meghan E. Flanigan, Min Cai, Jessica J. Walsh, Scott J. Russo, Eric J. Nestler, Erin S. Calipari, Allyson K. Friedman, Ming-Hu Han
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Anxiety and depression are highly comorbid, yet the distinct or shared neurobiological correlates of anxiety remain elusive. Here, Morel et al. define that the midbrain projection to the basolateral amygdala control anxiety but not depression.
Externí odkaz:
https://doaj.org/article/d94aa0f05915423889c5257d381347f6
Autor:
Qingbo Lu, Fangfang Wu, Jiao Jiao, Le Xue, Ruize Song, Yachen Shi, Yan Kong, Jianfei Sun, Ning Gu, Ming-Hu Han, Zhijun Zhang
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104201- (2022)
Summary: Emerging evidence suggests that dysfunction of the visual cortex may be involved in major depressive disorder (MDD). However, the underlying mechanisms remain unclear. We previously established that combined magnetic stimulation system treat
Externí odkaz:
https://doaj.org/article/84d36a0264d44e689098dd97a6e4b310
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2378 (2022)
Norepinephrine is a catecholamine neurotransmitter that has been extensively implicated in the neurobiology of major depressive disorder (MDD). An accumulating body of evidence indicates that investigations into the action of norepinephrine at the sy
Externí odkaz:
https://doaj.org/article/a02f3f715f4e4810b984814767c9fae7
Autor:
Efrain A. Ribeiro, Marine Salery, Joseph R. Scarpa, Erin S. Calipari, Peter J. Hamilton, Stacy M. Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L. Neve, Rosemary C. Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J. Nestler
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
While making up a small percentage of neurons in the nucleus accumbens, somatostatin interneurons may have important function in dopamine- and addiction-related behavior. Here, Ribeiro and colleagues show that somatostatin interneurons regulate behav
Externí odkaz:
https://doaj.org/article/de460a0a87ff48c7a645aa7091dbb3fb
Autor:
Jun Wang, Georgia E. Hodes, Hongxing Zhang, Song Zhang, Wei Zhao, Sam A. Golden, Weina Bi, Caroline Menard, Veronika Kana, Marylene Leboeuf, Marc Xie, Dana Bregman, Madeline L. Pfau, Meghan E. Flanigan, Adelaida Esteban-Fernández, Shrishailam Yemul, Ali Sharma, Lap Ho, Richard Dixon, Miriam Merad, Ming-Hu Han, Scott J. Russo, Giulio M. Pasinetti
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Polyphenols have partial antidepressant effect without known mechanism. Here, the authors identify two phytochemicals from bioactive dietary polyphenols, show their antidepressant effect in a rodent model of depression, and that this effect is mediat
Externí odkaz:
https://doaj.org/article/23f3bdbf01a249bd99070c55d3345edc
Autor:
Barbara Juarez, Carole Morel, Stacy M. Ku, Yutong Liu, Hongxing Zhang, Sarah Montgomery, Hilledna Gregoire, Efrain Ribeiro, Marshall Crumiller, Ciorana Roman-Ortiz, Jessica J. Walsh, Kelcy Jackson, Denise E. Croote, Yingbo Zhu, Song Zhang, Leandro F. Vendruscolo, Scott Edwards, Amanda Roberts, Georgia E. Hodes, Yongke Lu, Erin S. Calipari, Dipesh Chaudhury, Allyson K. Friedman, Ming-Hu Han
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Mice exposed to a two-bottle alcohol choice paradigm can be divided into high and low drinking groups. Here, the authors show that stimulating VTA neurons to induce higher phasic activity patterns that are observed in low alcohol drinking mice, suppr
Externí odkaz:
https://doaj.org/article/c7189739a90a4202b1484c7c8679ab16