Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Ming-Han Chen"'
Autor:
Huai-Chia Chuang, Chia-Hsin Hsueh, Pu-Ming Hsu, Ching-Yi Tsai, Ying-Chun Shih, Hsien-Yi Chiu, Yi-Ming Chen, Wen-Kuang Yu, Ming-Han Chen, Tse-Hua Tan
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Dual-specificity phosphatase 8 (DUSP8) is a MAPK phosphatase that dephosphorylates and inactivates the kinase JNK. DUSP8 is highly expressed in T cells; however, the in vivo role of DUSP8 in T cells remains unclear. Using T cell–specific Dusp8 cond
Externí odkaz:
https://doaj.org/article/f37e99b47c2e42e8982271f79bee0148
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Dual-specificity phosphatases (DUSPs) can dephosphorylate both tyrosine and serine/threonine residues of their substrates and regulate T cell-mediated immunity and autoimmunity. The aim of this study was to investigate the potenti
Externí odkaz:
https://doaj.org/article/5bdb14d1afbf4c02a1469beb2baccc6f
Autor:
Yen-Po Tsao, Fang-Yu Tseng, Chih-Wei Chao, Ming-Han Chen, Yi-Chen Yeh, Babamale Olarewaju Abdulkareem, Se-Yi Chen, Wen-Ting Chuang, Pei-Ching Chang, I-Chun Chen, Pin-Hsuan Wang, Chien-Sheng Wu, Chang-Youh Tsai, Szu-Ting Chen
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/fb91f1ce06e141e08e07dbbc5e66f9ee
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss 1 (2022)
Objective Diagnosis of SLE is based on clinical manifestations but is heterogeneous in early onset. Hence, we aimed to evaluate the feature of the immunoprofiling in patients with SLE and apply it to develop an immune signature algorithm for supporti
Externí odkaz:
https://doaj.org/article/c3bf259771164501861b28d43722be42
Autor:
Shih-Yun Wu, Ching-Yi Wu, Ming-Han Chen, Hsin-Yi Huang, Yu-hsuan Chen, Yen-Po Tsao, Yu-Lin Lai, Shih-Yuan Lee
Publikováno v:
Journal of Dental Sciences, Vol 16, Iss 4, Pp 1222-1232 (2021)
Sjögren's syndrome (SS) is a chronic autoimmune rheumatic disease characterized by a progressive lymphocytic infiltration of salivary glands, resulting in xerostomia and other oral diseases. The pathogenesis and mechanisms of SS on periodontal tissu
Externí odkaz:
https://doaj.org/article/58600e55fbc3428d9c570577a4e0f54d
Autor:
Shan-Fu Yu, Ming-Han Chen, Jia-Feng Chen, Yu-Wei Wang, Ying-Chou Chen, Chung-Yuan Hsu, Han-Ming Lai, Wen-Chan Chiu, Chi-Hua Ko, Hsiao-Ru He, Tien-Tsai Cheng
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 13 (2022)
Background: To establish a FRAX®-based prediction model for rheumatoid arthritis (RA)-associated fragility fracture. Methods: This study is a longitudinal, real-world, registry cohort study. Patients with RA were registered to start in September 201
Externí odkaz:
https://doaj.org/article/aa07e4ac830043a4a35d051479ec020c
Autor:
Ming-Han Chen, Shan-Fu Yu, Jia-Feng Chen, Wei-Sheng Chen, The-Ling Liou, Chung-Tei Chou, Chung-Yuan Hsu, Han-Ming Lai, Ying-Chou Chen, Chang-Youh Tsai, Tien-Tsai Cheng
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
ObjectiveTo compare changes in bone mineral density (BMD) in rheumatoid arthritis (RA) patients receiving three-year conventional synthetic disease-modifying anti-rheumatic drugs (csDMARD), tumor necrosis factor-α inhibitors (TNFi), and abatacept.Me
Externí odkaz:
https://doaj.org/article/05f4e47d12124530b1c058e88adc0d68
Autor:
Po-Chun Liu, Chih-Tai Ssu, Yen-Po Tsao, Teh-Ling Liou, Chang-Youh Tsai, Chung-Tei Chou, Ming-Han Chen, Chuen-Miin Leu
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background Cytotoxic T lymphocyte-associated antigen-4-Ig (CTLA-4-Ig) competes with CD28 for binding CD80/CD86 on antigen-presenting cells (APCs) to limit T cell activation. B cells are believed to be important APCs in the pathogenesis of au
Externí odkaz:
https://doaj.org/article/54411dbe04fb4ab1b44cd1a954ff2836
Autor:
Ming-Han Chen, Ming-Ting Huang, Wen-Kuang Yu, Shinn-Shing Lee, Jia-Horng Wang, Ting-Jen R. Cheng, Michael R. Bowman, Shie-Liang Hsieh
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-12 (2019)
Abstract Background Dectin-2, which is a C-type lectin, interacts with the house dust mite (HDM) Dermatophagoides pteronyssinus allergen. This study aimed to investigate whether Dectin-2 blockade by antagonistic monoclonal antibodies (MoAbs) attenuat
Externí odkaz:
https://doaj.org/article/c062eb9bc197464890eb2f07a165030d
Autor:
MingLi Hung, Deh-Feng Huang, Wei-Sheng Chen, Chien-Chih Lai, Ming-Han Chen, Hsien-Tzung Liao, Chang-Youh Tsai
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 52, Iss 1, Pp 114-121 (2019)
Background: The clinical features and outcomes of cytomegalovirus (CMV) diseases in patients with systemic lupus erythematosus (SLE) are unknown. We analyzed such data from a medical center in Taiwan. Methods: We retrospectively reviewed the medical
Externí odkaz:
https://doaj.org/article/8624b621604b434782dbdb0a0a00a8d1