Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ming-Fo Hsu"'
Autor:
Ming-Fo Hsu, Shinichiro Koike, Chang-Shan Chen, Sonia M. Najjar, Tzu-Ching Meng, Fawaz G. Haj
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116590- (2024)
Alcohol-associated liver disease (ALD) is a leading factor of liver-related death worldwide. ALD has various manifestations that include steatosis, hepatitis, and cirrhosis and is currently without approved pharmacotherapies. The Src homology phospha
Externí odkaz:
https://doaj.org/article/7b38d6406b504e55b22e233feeb4e9be
Autor:
Aline Mello, Ming-Fo Hsu, Shinichiro Koike, Bryan Chu, Jeff Cheng, Jun Yang, Christophe Morisseau, Natalie J. Torok, Bruce D. Hammock, Fawaz G. Haj
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 815-830 (2021)
Background & Aims: Alcohol-associated liver disease (ALD) is a significant cause of liver-related morbidity and mortality worldwide and with limited therapies. Soluble epoxide hydrolase (sEH; Ephx2) is a largely cytosolic enzyme that is highly expres
Externí odkaz:
https://doaj.org/article/010aa7f991b54df68a730bdad2aaaead
Publikováno v:
Redox Biology, Vol 36, Iss , Pp 101658- (2020)
Alcoholic liver disease (ALD) is a major health problem and a significant cause of liver-related death. Currently, the mainstay for ALD therapy is alcohol abstinence highlighting the need to develop pharmacotherapeutic approaches. Protein-tyrosine ph
Externí odkaz:
https://doaj.org/article/37edabe68a404a0db9c5c82568bfa310
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Podocytes are specialized epithelial cells that play a significant role in maintaining the integrity of the glomerular filtration barrier and preventing urinary protein leakage. We investigated the contribution of protein tyrosine phosphatas
Externí odkaz:
https://doaj.org/article/596de7c5fb144f74bc697024e074dc19
Autor:
Ming-Fo Hsu, 徐銘佛
98
Enzymes in the protein tyrosine phosphatase (PTP) superfamily are involved in the regulation of many aspects of biological processes. The catalytic activity of PTPs is mediated by an invariant Cys residue, which has a remarkably low pKa, ther
Enzymes in the protein tyrosine phosphatase (PTP) superfamily are involved in the regulation of many aspects of biological processes. The catalytic activity of PTPs is mediated by an invariant Cys residue, which has a remarkably low pKa, ther
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/28894300698434482551
Publikováno v:
Cellular and Molecular Life Sciences. 79
Diabetic nephropathy (DN) is a significant complication of diabetes and the leading cause of end-stage renal disease. Hyperglycemia-induced dysfunction of the glomerular podocytes is a major contributor to the deterioration of renal function in DN. P
Autor:
Bruce D. Hammock, A. F. S. Mello, Natalie J. Török, Fawaz G. Haj, Jun Yang, Ming-Fo Hsu, Bryan Chu, Christophe Morisseau, Jeff Cheng, Shinichiro Koike
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 815-830 (2021)
Cellular and molecular gastroenterology and hepatology, vol 11, iss 3
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 11, iss 3
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Alcohol-associated liver disease (ALD) is a significant cause of liver-related morbidity and mortality worldwide and with limited therapies. Soluble epoxide hydrolase (sEH; Ephx2) is a largely cytosolic enzyme that is highly express
Autor:
Bryan Chu, Fawaz G. Haj, Ming-Fo Hsu, Peter J. Havel, Mark O. Huising, Christophe Morisseau, Bruce D. Hammock, Shinichiro Koike, Ahmed Bettaieb, Naoki Matsumoto
Publikováno v:
Free Radic Biol Med
Pancreatic β-cells are crucial regulators of systemic glucose homeostasis, and their dysfunction and loss are central features in type 2 diabetes. Interventions that rectify β-cell dysfunction and loss are essential to combat this deadly malady. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3daea74f9ae1f66e04517256832dd1
https://escholarship.org/uc/item/03b8h68k
https://escholarship.org/uc/item/03b8h68k
Protein tyrosine phosphatase 1B deficiency in podocytes mitigates hyperglycemia-induced renal injury
Autor:
Yoshihiro Ito, Miguel Calvo-Rubio, Shinichiro Koike, Ahmed Bettaieb, A. F. S. Mello, José M. Villalba, Ming-Fo Hsu, Fawaz G. Haj
Publikováno v:
Metabolism. 76:56-69
Objective Diabetic nephropathy is one of the most devastating complications of diabetes, and growing evidence implicates podocyte dysfunction in disease pathogenesis. The objective of this study was to investigate the contribution of protein tyrosine