Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ming-Chao Zhong"'
Autor:
Rui Li, Cristian Camilo Galindo, Dominique Davidson, Huaijian Guo, Ming-Chao Zhong, Jin Qian, Bin Li, Zsolt Ruzsics, Colleen M. Lau, Timothy E. O'Sullivan, Silvia M. Vidal, Joseph C. Sun, André Veillette
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113800- (2024)
Summary: Infection of mice by mouse cytomegalovirus (MCMV) triggers activation and expansion of Ly49H+ natural killer (NK) cells, which are virus specific and considered to be “adaptive” or “memory” NK cells. Here, we find that signaling lymp
Externí odkaz:
https://doaj.org/article/adb6c93e5f704d00b240fb56f26c9322
Autor:
Zhenghai Tang, Dominique Davidson, Rui Li, Ming-Chao Zhong, Jin Qian, Jun Chen, André Veillette
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110111- (2021)
Summary: Blockade of the inhibitory checkpoint SIRPα-CD47 promotes phagocytosis of cancer cells by macrophages and is a promising avenue in anti-cancer therapy. Productive phagocytosis is strictly predicated on co-engagement of pro-phagocytic recept
Externí odkaz:
https://doaj.org/article/b4b262305880494d84b80c48aa485fbb
Autor:
Bin Li, Yan Lu, Ming-Chao Zhong, Jin Qian, Rui Li, Dominique Davidson, Zhenghai Tang, Kaiwen Zhu, Jérémy Argenty, Anne Gonzalez de Peredo, Bernard Malissen, Romain Roncagalli, André Veillette
Publikováno v:
Science Immunology
Science Immunology, 2022, 7 (74), ⟨10.1126/sciimmunol.abn6373⟩
Science Immunology, 2022, 7 (74), ⟨10.1126/sciimmunol.abn6373⟩
International audience; CD2 is largely described to promote T cell activation when engaged by its ligands, CD48 in mice and CD58 in humans, that are present on antigen-presenting cells (APCs). However, both CD48 and CD58 are also expressed on T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d62673f67a1c599119c138cc9bbe62
https://hal.science/hal-03867882
https://hal.science/hal-03867882
Autor:
Jinsam Chang, Woong-Kyung Suh, Joanna Li, Won Seog Kim, André Veillette, Thorsten Buch, Seok Jin Kim, Yasser Bouklouch, Young Hyeh Ko, Mariko Witalis, Vincent Panneton, Ming-Chao Zhong
Publikováno v:
Blood Advances. 4:868-879
Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive peripheral T-cell lymphoma driven by a pool of neoplastic cells originating from T follicular helper (Tfh) cells and concomitant expansion of B cells. Conventional chemotherapies for AITL hav
Autor:
Denis Faubert, Marija Landekic, Sonia Marin, Julia Luo, Alexis Blanchet-Cohen, Maziar Divangahi, Brinley R. Ford, Lucie Roussel, William D. Foulkes, Marc-Antoine Parent, Ming-Chao Zhong, André Veillette, Donald C. Vinh, Catherine Le, Luc Dansereau, Irah L. King, Christina Gavino, Mélanie J. Langelier, Makan Golizeh, Jun Chen
Publikováno v:
médecine/sciences. 35:625-628
Autor:
Julia Luo, Marija Landekic, André Veillette, Alexis Blanchet-Cohen, William D. Foulkes, Sonia Marin, Christina Gavino, Makan Golizeh, Denis Faubert, Mélanie Langelier, Brinley R. Ford, Maziar Divangahi, Donald C. Vinh, Irah L. King, Jun Chen, Marc-Antoine Parent, Catherine Le, Ming-Chao Zhong, Luc Dansereau, Lucie Roussel
Publikováno v:
The Journal of Experimental Medicine
Roussel et al. identify the first patient with autosomal recessive deficiency in ICOSLG, the gene encoding the ligand for ICOS. The missense allele impairs cell surface expression of ICOSL, compromises T–B lymphocyte costimulation, and results in c
Autor:
Jin Qian, Lingli Dong, Astrid Zahn, André Veillette, Irah L. King, Danielle Karo-Atar, Yan Lu, Javier M. Di Noia, Yingzi Zhu, Ming-Chao Zhong
Publikováno v:
The Journal of Experimental Medicine
SLAM family receptors are involved in humoral immune regulation. In this issue of JEM, Zhong et al. provide evidence that these receptors collectively suppress germinal center reaction but promote production of antigen-specific antibodies.
SLAM
SLAM
Autor:
Clifford A. Lowell, Virginie Calderon, Ming-Chao Zhong, Ning Wu, Shaohua Zhang, Dominique Davidson, Sabrin Mishel, Mario-Ernesto Cruz-Munoz, Luis-Alberto Pérez-Quintero, Jun Chen, Huaijian Guo, Inmoo Rhee, Meenal Sinha, Jayne S. Danska, André Veillette, Donald C. Vinh, Yan Lu
Publikováno v:
Nature. 544:493-497
Cancer cells elude anti-tumour immunity through multiple mechanisms, including upregulated expression of ligands for inhibitory immune checkpoint receptors1,2. Phagocytosis by macrophages plays a critical role in cancer control3–6. Therapeutic bloc
Autor:
André Veillette, Dominique Davidson, Hua Gu, Xin Li, Ming-Chao Zhong, Silvia Bolland, Pier Paolo Pandolfi, Ramnik J. Xavier, Brian Seed
Publikováno v:
Elsevier
Summary - The transmembrane adaptor PAG (Cbp) has been proposed to mediate membrane recruitment of Csk, a cytoplasmic protein tyrosine kinase playing a critical inhibitory role during T cell activation, by inactivating membrane-associated Src kinases
Autor:
Zhanguang Zhang, Christelle Lenoir, Zhongjun Dong, Luis-Alberto Pérez-Quintero, Huaijian Guo, Ming-Chao Zhong, André Veillette, Ning Wu, Sylvain Latour, Romain Roncagalli
Publikováno v:
Nature Immunology. 17:387-396
Activation of natural killer (NK) cells by hematopoietic target cells is controlled by the SLAM family of receptors and by the associated SAP family of adaptors. Here we found that SLAM receptors also enhanced NK cell activation by nonhematopoietic t