Výsledky vyhledávání - "Ming-Biao Wei"

Akademický článek

MRNIP condensates promote DNA double-strand break sensing and end resection

Autor: Yun-Long Wang, Wan-Wen Zhao, Shao-Mei Bai, Li-Li Feng, Shu-Ying Bie, Li Gong, Fang Wang, Ming-Biao Wei, Wei-Xing Feng, Xiao-Lin Pang, Cao-Litao Qin, Xin-Ke Yin, Ying-Nai Wang, Weihua Zhou, Daniel R. Wahl, Quentin Liu, Ming Chen, Mien-Chie Hung, Xiang-Bo Wan

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

The MRN complex is a critical sensor and processor of DNA double-strand breaks (DSBs). Here, the authors show that MRNIP forms liquid-like condensates to accelerate the MRN-mediated sensing and end resection of DSB, thereby promoting DSB repair.

Externí odkaz: https://doaj.org/article/0d2d630dc0a747b8807be46604e76da1

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Akademický článek

The watch-and-wait strategy versus surgical resection for rectal cancer patients with a clinical complete response after neoadjuvant chemoradiotherapy

Autor: Qiao-xuan Wang, Rong Zhang, Wei-wei Xiao, Shu Zhang, Ming-biao Wei, Yong-heng Li, Hui Chang, Wei-hao Xie, Li-ren Li, Pei-rong Ding, Gong Chen, Zhi-fan Zeng, Wei-hu Wang, Xiang-bo Wan, Yuan-hong Gao

Publikováno v: Radiation Oncology, Vol 16, Iss 1, Pp 1-8 (2021)

Abstract Background The watch-and-wait strategy offers a non-invasive therapeutic alternative for rectal cancer patients who have achieved a clinical complete response (cCR) after chemoradiotherapy. This study aimed to investigate the long-term clini

Externí odkaz: https://doaj.org/article/babda910c4bb48308aaf8a3cb193ba1f

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PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer

Publikováno v: Oncogene

Arginine methylation is an important posttranslational modification catalyzed by protein arginine methyltransferases (PRMTs). However, the role of PRMTs in colorectal cancer (CRC) progression is not well understood. Here we report that non-POU domain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be130a9de8d6fed76d135093fe2877c3
http://europepmc.org/articles/PMC7892343

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Epidermal growth factor receptor stabilizes programmed death ligand 1 by glycosylation in colorectal cancer with microstatellite instability status

Autor: Yi-Kan Cheng, Xin-Ke Yin, Shao-Mei Bai, Wang Yunlong, Xiang-Bo Wan, Xinjuan Fan, Haiyang Chen, Jian Zheng, Fang He, Xiaolin Pang, Dalu Zhang, Shuai Liu, Ming-Biao Wei, Lei Wang, Wan-Wen Zhao, Wei-Xing Feng, Junxiang Yin, Li-Li Feng

Publikováno v: Journal of Bio-X Research, Vol 2, Iss 1, Pp 1-8 (2019)

Programmed death ligand-1 (PD-L1) is involved in inhibiting of T lymphocyte proliferation, producing cytokine, cytolytic activity, and suppressing of the immune response. Genes with molecular alterations involved in DNA mismatch repair promote cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e93cd0b909f6d941ce03d775776b44
http://journals.lww.com/10.1097/JBR.0000000000000025

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MRNIP condensates promote DNA double-strand break sensing and end resection

Publikováno v: Nature communications. 13(1)

The rapid recognition of DNA double-strand breaks (DSBs) by the MRE11/RAD50/NBS1 (MRN) complex is critical for the initiation of DNA damage response and DSB end resection. Here, we show that MRN complex interacting protein (MRNIP) forms liquid-like c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70457948559196bed4ddf8a076c8e3a5
https://pubmed.ncbi.nlm.nih.gov/35551189

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Additional file 1 of The watch-and-wait strategy versus surgical resection for rectal cancer patients with a clinical complete response after neoadjuvant chemoradiotherapy

Autor: Qiao-Xuan Wang, Zhang, Rong, Xiao, Wei-Wei, Zhang, Shu, Ming-Biao Wei, Li, Yong-Heng, Chang, Hui, Wei-Hao Xie, Li, Li-Ren, Ding, Pei-Rong, Chen, Gong, Zeng, Zhi-Fan, Wei-Hu Wang, Wan, Xiang-Bo, Gao, Yuan-Hong

Additional file 1. S1: Characteristics of patients according to treatment group (non-matched cohort). S2: Number and location of distant metastasis in the matched groups. S3: Distant metastasis-free survival (A), non-regrowth disease-free survival (B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5602ebcb576f6c5b27de5ba42886d0

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The watch-and-wait strategy versus surgical resection for rectal cancer patients with a clinical complete response after neoadjuvant chemoradiotherapy

Autor: Pei-Rong Ding, Zhifan Zeng, Yuanhong Gao, Gong Chen, Liren Li, Rong Zhang, Shu Zhang, Yongheng Li, Weiwei Xiao, Weihu Wang, Qiaoxuan Wang, Wei-Hao Xie, Ming-biao Wei, Hui Chang, Xiang-Bo Wan

Publikováno v: Radiation Oncology (London, England)
Radiation Oncology, Vol 16, Iss 1, Pp 1-8 (2021)

BackgroundThe watch-and-wait strategy offers a non-invasive therapeutic alternative for rectal cancer patients who have achieved a clinical complete response (cCR) after chemoradiotherapy. This study aimed to investigate the long-term clinical outcom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b5f4e772b94fa97c55b8979d824ba1
http://europepmc.org/articles/PMC7816381

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College of American Pathologists Tumor Regression Grading System for Long-Term Outcome in Patients with Locally Advanced Rectal Cancer

Publikováno v: Oncologist

Background The National Comprehensive Cancer Network's Rectal Cancer Guideline Panel recommends American Joint Committee of Cancer and College of American Pathologists (AJCC/CAP) tumor regression grading (TRG) system to evaluate pathologic response t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb015e339e310a29bec6dc7854fb4a7
https://pubmed.ncbi.nlm.nih.gov/33543577

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Watch-and-wait Strategy against Surgical Resection for Rectal Cancer Patients with Complete Clinical Response after Neoadjuvant Chemoradiotherapy

Autor: Pei-Rong Ding, Yuanhong Gao, Wei-Hao Xie, Xiang-Bo Wan, Zhifan Zeng, Ming-biao Wei, Liren Li, Wei-hu Wang, Yong-heng Li, Rui-Hua Xu, Zhenhai Lu, Qiaoxuan Wang, Hui Chang, Rong Zhang, Xiaojun Wu, Shu Zhang, Weiwei Xiao, Gong Chen, Zhizhong Pan

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 108:e596

Background: The watch-and-wait strategy offers a non-invasive therapeutic alternative for rectal cancer patients who achieved clinical complete response (cCR) after chemoradiotherapy. However, concerns about the safety of this treatment strategy rema

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2618d9fbb7ab9776d6e2cae5f6c18d
https://doi.org/10.1016/j.ijrobp.2020.07.1821

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