Multi-target modulation of ion channels underlying the analgesic effects of α-mangostin in dorsal root ganglion neurons

Autor: Sung Eun Kim, Ming Zhe Yin, Jae Won Roh, Hyun Jong Kim, Seong Woo Choi, Brian J. Wainger, Woo Kyung Kim, Sung Joon Kim, Joo Hyun Nam

Publikováno v: Phytomedicine. 115:154791

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21386157401ca4b331a8fac73b882ac9
https://doi.org/10.1016/j.phymed.2023.154791

Increased inward rectifier K + current of coronary artery smooth muscle cells in spontaneously hypertensive rats; partial compensation of the attenuated endothelium‐dependent relaxation via Ca 2+ ‐activated K + channels

Autor: Hae Jin Kim, Ming Zhe Yin, Suhan Cho, Seong Woo Choi, Sung Joon Kim, Hae Young Yoo, Sung Eun Kim, Sang Kyu Ye

Publikováno v: Clinical and Experimental Pharmacology and Physiology. 47:38-48

Endothelium-dependent vasorelaxation is partly mediated by small-conductance (SK3) and intermediate-conductance Ca2+ -activated K+ channels (SK4) in the endothelium that results in endothelium-dependent hyperpolarization (EDH). Apart from the electri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a7dd06d6e1934c3e09bd95f16990fc3
https://doi.org/10.1111/1440-1681.13168

Neuronal nitric oxide synthase modulation of intracellular Ca2+ handling overrides fatty acid potentiation of cardiac inotropy in hypertensive rats

Autor: Chae Hun Leem, Yue Wang, Chun Zi Jin, Sung Joon Kim, Jeong Hoon Lee, Yin Hua Zhang, Chun Li Jin, Jin Chul Paeng, Zai Hao Zhao, Jong Wan Park, Ming Zhe Yin, Seunggyun Ha, Keon Wook Kang, Peng Jin

Publikováno v: Jin, C L, Yin, M Z, Paeng, J C, Seunggyun, H, Lee, J H, Jin, P, Jin, C Z, Hao Zhao, Z, Wang, Y, Kang, K W, Leem, C H, Park, J-W, Kim, S J & Zhang, Y 2017, ' Neuronal nitric oxide synthase modulation of intracellular Ca 2+ handling overrides fatty acid-potentiation of cardiac inotropy in hypertensive rats ', Pflügers Archiv European Journal of Physiology, pp. 1-13 . https://doi.org/10.1007/s00424-017-1991-1

Cardiac neuronal nitric oxide synthase (nNOS) is an important molecule that regulates intracellular Ca2+ homeostasis and contractility of healthy and diseased hearts. Here, we examined the effects of nNOS on fatty acid (FA) regulation of left ventric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb36a981f6c59bc464ab84a49329242
https://doi.org/10.1007/s00424-017-1991-1

Activation of K⁺ channel by 1-EBIO rescues the head and neck squamous cell carcinoma cells from Ca²⁺ ionophore-induced cell death.

Autor: Ming Zhe Yin^1,2,3, Seok-Woo Park^4,5 sjoonkim@snu.ac.kr, Tae Wook Kang¹, Kyung Soo Kim^1,2,3, Hae Young Yoo⁶, Junho Lee⁴, J. Hun Hah^4,5, Myung Hun Sung^4,5, Sung Joon Kim^1,2,3

Publikováno v: Korean Journal of Physiology & Pharmacology. 2016, Vol. 20 Issue 1, p25-33. 9p.

Decreased inward rectifier and voltage-gated K+ currents of the right septal coronary artery smooth muscle cells in pulmonary arterial hypertensive rats

Autor: Ming Zhe Yin, Sung Joon Kim, Hae Jin Kim, Hae Young Yoo, Sung Eun Kim, Rany Vorn

Publikováno v: The Korean Journal of Physiology & Pharmacology. 24:111

In vascular smooth muscle, K+ channels, such as voltage-gated K+ channels (Kv), inward-rectifier K+ channels (Kir), and big-conductance Ca2+-activated K+ channels (BKCa), establish a hyperpolarized membrane potential and counterbalance the depolarizi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82d0cc612634ef7012f5ce3dab536bdc
https://doi.org/10.4196/kjpp.2020.24.1.111