Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ming Ru Wu"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 3, Pp 155-155 (2019)
OBJECTIVES/SPECIFIC AIMS: Glioblastoma (GBM) is a brain cancer with a devastatingly short overall survival of under two years. The poor prognosis of GBM is largely due to cell invasion and maintenance of cancer initiating cells that evade the brain
Externí odkaz:
https://doaj.org/article/b9e8f8ff1b014f499ddd9ae4bc9ac00e
Autor:
William C. W. Chen, Leonid Gaidukov, Yong Lai, Ming-Ru Wu, Jicong Cao, Michael J. Gutbrod, Gigi C. G. Choi, Rachel P. Utomo, Ying-Chou Chen, Liliana Wroblewska, Manolis Kellis, Lin Zhang, Ron Weiss, Timothy K. Lu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Precise and scalable regulation of gene expression in mammalian cells is challenging. Here, the authors created a highly tunable CRISPR-based synthetic transcription system for programmable control of mammalian gene expression and cellular activity.
Externí odkaz:
https://doaj.org/article/310dc9b5a9a34df28dfb75c848485687
Autor:
Ming-Ru Wu, Lior Nissim, Doron Stupp, Erez Pery, Adina Binder-Nissim, Karen Weisinger, Casper Enghuus, Sebastian R. Palacios, Melissa Humphrey, Zhizhuo Zhang, Eva Maria Novoa, Manolis Kellis, Ron Weiss, Samuel D. Rabkin, Yuval Tabach, Timothy K. Lu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Synthetic promoters can be superior to native ones but the design is challenging without knowledge of gene regulation. Here the authors develop a pipeline that allows for screening a synthetic promoter library to identify high performance promoters i
Externí odkaz:
https://doaj.org/article/4058b7f205214aa99e7ffdf21a5903d9
Autor:
Da-Hua Wei, Sheng-Kai Tong, Sheng-Chiang Chen, Yong-Han Hao, Ming-Ru Wu, Cheng-Jie Yang, Rong-Tan Huang, Ren-Jei Chung
Publikováno v:
Nanomaterials, Vol 12, Iss 15, p 2575 (2022)
The surface plasmonic resonance, surface wettability, and related mechanical nanohardness and of face-centered-cubic (fcc) chromium nitride (CrN) films have been successfully manipulated via the simple method of tuning nitrogen-containing gas with di
Externí odkaz:
https://doaj.org/article/cf06deaf34f942069bd9e68c5cbaac4d
Autor:
Jicong Cao, Pablo Perez-Pinera, Ky Lowenhaupt, Ming-Ru Wu, Oliver Purcell, Cesar de la Fuente-Nunez, Timothy K. Lu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The ability to combine the production of multiple biologics into a single ‘on demand’ system could help in situations where resources are limited. Here the authors demonstrate a proof-of-concept approach for the co-production of three biologics,
Externí odkaz:
https://doaj.org/article/6a69703c022e40fcb360d33fd32745bf
Publikováno v:
Journal of Biological Chemistry. 299:104335
Autor:
Michael E Johnson, J Matthew Mahoney, Jaclyn Taroni, Jennifer L Sargent, Eleni Marmarelis, Ming-Ru Wu, John Varga, Monique E Hinchcliff, Michael L Whitfield
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0114017 (2015)
Genome-wide expression profiling in systemic sclerosis (SSc) has identified four 'intrinsic' subsets of disease (fibroproliferative, inflammatory, limited, and normal-like), each of which shows deregulation of distinct signaling pathways; however, th
Externí odkaz:
https://doaj.org/article/190c1ebe5bba49acaa2d11bc4f958758
Autor:
William C.W. Chen, Leonid Gaidukov, Yong Lai, Ming-Ru Wu, Jicong Cao, Michael J. Gutbrod, Gigi C.G. Choi, Rachel P. Utomo, Ying-Chou Chen, Liliana Wroblewska, Manolis Kellis, Lin Zhang, Ron Weiss, Timothy K. Lu
Publikováno v:
Nature communications. 13(1)
Precise, scalable, and sustainable control of genetic and cellular activities in mammalian cells is key to developing precision therapeutics and smart biomanufacturing. We created a highly tunable, modular, versatile CRISPR-based synthetic transcript
Autor:
Oliver Purcell, Pablo Perez-Pinera, Ming-Ru Wu, Ky Lowenhaupt, Cesar de la Fuente-Nunez, Timothy K. Lu, Jicong Cao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
Current limitations to on-demand drug manufacturing can be addressed by technologies that streamline manufacturing processes. Combining the production of two or more drugs into a single batch could not only be useful for research, clinical studies, a
Publikováno v:
Applied Surface Science. 564:150091
In this work, a simple and effective method with different thicknesses in the ranges of 100–300 nm of insulating layer was investigated to enhance the performance of resistive switching behavior in polymetallic oxide-based spinel nickel ferrite (Ni