Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Ming Poi"'
Autor:
Ji Young Kim, Yuntao Bai, Laura A. Jayne, Ralph D. Hector, Avinash K. Persaud, Su Sien Ong, Shreshtha Rojesh, Radhika Raj, Mei Ji He Ho Feng, Sangwoon Chung, Rachel E. Cianciolo, John W. Christman, Moray J. Campbell, David S. Gardner, Sharyn D. Baker, Alex Sparreboom, Rajgopal Govindarajan, Harpreet Singh, Taosheng Chen, Ming Poi, Katalin Susztak, Stuart R. Cobb, Navjot Singh Pabla
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Protein kinases have emerged as critical regulators of disease pathogenesis. Here, the authors have utilized kinome-wide screening approaches to reveal a pathogenic role of CDKL5 kinase in acute kidney injury, which is dependent on suppression of a S
Externí odkaz:
https://doaj.org/article/f36413dcdc0f4c47bbdac00ac1a34b20
Autor:
Long-Sheng Chang, Janet L Oblinger, Abbi E Smith, Marc Ferrer, Steven P Angus, Eric Hawley, Alejandra M Petrilli, Roberta L Beauchamp, Lars Björn Riecken, Serkan Erdin, Ming Poi, Jie Huang, Waylan K Bessler, Xiaohu Zhang, Rajarshi Guha, Craig Thomas, Sarah S Burns, Thomas S K Gilbert, Li Jiang, Xiaohong Li, Qingbo Lu, Jin Yuan, Yongzheng He, Shelley A H Dixon, Andrea Masters, David R Jones, Charles W Yates, Stephen J Haggarty, Salvatore La Rosa, D Bradley Welling, Anat O Stemmer-Rachamimov, Scott R Plotkin, James F Gusella, Justin Guinney, Helen Morrison, Vijaya Ramesh, Cristina Fernandez-Valle, Gary L Johnson, Jaishri O Blakeley, D Wade Clapp, Synodos for NF2 Consortium
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0252048 (2021)
Neurofibromatosis Type 2 (NF2) is an autosomal dominant genetic syndrome caused by mutations in the NF2 tumor suppressor gene resulting in multiple schwannomas and meningiomas. There are no FDA approved therapies for these tumors and their relentless
Externí odkaz:
https://doaj.org/article/d5cdd322a442449ebaffcbfad82ea6a3
Autor:
Naifa L. Busaidy, Bhavana Konda, Lai Wei, Lori J. Wirth, Catherine Devine, Gregory A. Daniels, Jonas A. DeSouza, Ming Poi, Nathan D. Seligson, Maria E. Cabanillas, Jennifer A. Sipos, Matthew D. Ringel, Ann-Kathrin Eisfeld, Cynthia Timmers, Manisha H. Shah
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 32(10)
lt;bgt;lt;igt;Background:lt;/igt;lt;/bgt; Oncogenic BRAF mutations are commonly found in advanced differentiated thyroid cancer (DTC), and reports have shown efficacy of BRAF inhibitors in these tumors. We investigated the difference in response betw
Autor:
Ernest Duah, Nathan D. Seligson, Avinash K. Persaud, Quynh Dam, Navjot Pabla, James W. Rocco, Junan Li, Ming Poi
Publikováno v:
Molecular Carcinogenesis.
Autor:
William E. Carson, Robert J. Lee, Michael A. Caligiuri, John C. Byrd, Susheela Tridandapani, Mitch Phelps, Ming Poi, Jonathan P. Butchar, David Jarjoura, Melanie Davis, Hsaioyin Mao, Xueliang Pan, Xiaoli Zhang, Yanhui Lu, Alessandra C. Schmitt, Krista M. La Perle, Saranya Elavazhagan, Jilong Li, Hong Li, Volodymyr Karpa, Julie Roda, Aruna Mani, Natalie B. Jones, Eric Luedke, Bethany L. Mundy-Bosse, Cassandra C. Skinner, SriVidya Kondadasula, Elizabeth L. McMichael, Alena C. Jaime-Ramirez
Optimally effective antitumor therapies would not only activate immune effector cells but also engage them at the tumor. Folate conjugated to immunoglobulin (F-IgG) could direct innate immune cells with Fc receptors to folate receptor–expressing ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c371a84cc247c90f7e4a2639d239de02
https://doi.org/10.1158/2326-6066.c.6548893
https://doi.org/10.1158/2326-6066.c.6548893
Autor:
William E. Carson, Robert J. Lee, Michael A. Caligiuri, John C. Byrd, Susheela Tridandapani, Mitch Phelps, Ming Poi, Jonathan P. Butchar, David Jarjoura, Melanie Davis, Hsaioyin Mao, Xueliang Pan, Xiaoli Zhang, Yanhui Lu, Alessandra C. Schmitt, Krista M. La Perle, Saranya Elavazhagan, Jilong Li, Hong Li, Volodymyr Karpa, Julie Roda, Aruna Mani, Natalie B. Jones, Eric Luedke, Bethany L. Mundy-Bosse, Cassandra C. Skinner, SriVidya Kondadasula, Elizabeth L. McMichael, Alena C. Jaime-Ramirez
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88307b978bdee4c4227e473bd6e6dd51
https://doi.org/10.1158/2326-6066.22538788
https://doi.org/10.1158/2326-6066.22538788
Autor:
William E. Carson, Robert J. Lee, Michael A. Caligiuri, John C. Byrd, Susheela Tridandapani, Mitch Phelps, Ming Poi, Jonathan P. Butchar, David Jarjoura, Melanie Davis, Hsaioyin Mao, Xueliang Pan, Xiaoli Zhang, Yanhui Lu, Alessandra C. Schmitt, Krista M. La Perle, Saranya Elavazhagan, Jilong Li, Hong Li, Volodymyr Karpa, Julie Roda, Aruna Mani, Natalie B. Jones, Eric Luedke, Bethany L. Mundy-Bosse, Cassandra C. Skinner, SriVidya Kondadasula, Elizabeth L. McMichael, Alena C. Jaime-Ramirez
Supplemental Figure 1.F‑IgG and IL-12 mediated NK cell lysis is dependent on the folate receptor availability and does not correlate with FcR genotype. Supplemental Figure 2. MDSC inhibit NK cell lytic activity and IFN-y production. Supplement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689f6c67521308f2647a4861bc567089
https://doi.org/10.1158/2326-6066.22538791
https://doi.org/10.1158/2326-6066.22538791
Autor:
Mitch A. Phelps, Michael R. Grever, John C. Byrd, Amy J. Johnson, Yuan Zhao, Ming Poi, Amy S. Ruppert, Kristie A. Blum, Diane R. Mould, Jia Ji
PDF file - 255 KB, Figure 1. Flavopiridol conditional weighted residuals vs. time with a smoothed loess line. Figure 2. Flavopiridol conditional weighted residuals vs. population predicted values with a smoothed loess line. Figure 3. Visual predictiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd9a9aa5e2f081aa51ad4d7bd80d07b
https://doi.org/10.1158/1078-0432.22448223
https://doi.org/10.1158/1078-0432.22448223
Autor:
Mitch A. Phelps, Michael R. Grever, John C. Byrd, Amy J. Johnson, Yuan Zhao, Ming Poi, Amy S. Ruppert, Kristie A. Blum, Diane R. Mould, Jia Ji
PDF file - 51 KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d333c8ef85014298eb9a54bca8a02b
https://doi.org/10.1158/1078-0432.22448226
https://doi.org/10.1158/1078-0432.22448226
Autor:
Mitch A. Phelps, Michael R. Grever, John C. Byrd, Amy J. Johnson, Yuan Zhao, Ming Poi, Amy S. Ruppert, Kristie A. Blum, Diane R. Mould, Jia Ji
Purpose: Flavopiridol, the first clinically evaluated cyclin-dependent kinase inhibitor, shows activity in patients with refractory chronic lymphocytic leukemia, but prevalent and unpredictable tumor lysis syndrome (TLS) presents a major barrier to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f18a6ff9f75be1fbd997bf5a09f0b9e
https://doi.org/10.1158/1078-0432.c.6521337.v1
https://doi.org/10.1158/1078-0432.c.6521337.v1