Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ming Lang Zhao"'
Autor:
Zhongliang Jiang, Yanhao Lai, Jill M. Beaver, Pawlos S. Tsegay, Ming-Lang Zhao, Julie K. Horton, Marco Zamora, Hayley L. Rein, Frank Miralles, Mohammad Shaver, Joshua D. Hutcheson, Irina Agoulnik, Samuel H. Wilson, Yuan Liu
Publikováno v:
Cells, Vol 9, Iss 1, p 225 (2020)
DNA damage and base excision repair (BER) are actively involved in the modulation of DNA methylation and demethylation. However, the underlying molecular mechanisms remain unclear. In this study, we seek to understand the mechanisms by exploring the
Externí odkaz:
https://doaj.org/article/788c11cb8b9c443193a8998431ba13e9
Autor:
Ming-Lang Zhao, Donna F. Stefanick, Cristina A. Nadalutti, William A. Beard, Samuel H. Wilson, Julie K. Horton
Publikováno v:
DNA Repair. 126:103486
Publikováno v:
J Biol Chem
DNA polymerase (pol) β catalyzes two reactions at DNA gaps generated during base excision repair, gap-filling DNA synthesis and lyase-dependent 5´-end deoxyribose phosphate removal. The lyase domain of pol β has been proposed to function in DNA ga
Autor:
Cristina A. Nadalutti, Julie K. Horton, Donna F. Stefanick, Ashley M. Brooks, Rajendra Prasad, Ming-Lang Zhao, Jack D. Griffith, Samuel H. Wilson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Formaldehyde (FA) is a simple biological aldehyde that is produced inside cells by several processes such as demethylation of DNA and proteins, amino acid metabolism, lipid peroxidation and one carbon metabolism (1-C). Although accumulation of excess
Autor:
Julie K, Horton, Agnes K, Janoshazi, Cristina A, Nadalutti, Ming-Lang, Zhao, Donna F, Stefanick, Samuel H, Wilson
Publikováno v:
DNA Repair. 116:103357
Mouse fibroblasts lacking (null) DNA polymerase β (pol β) were transfected with fluorescently tagged pol β and stained with biomarkers to allow visualization within living cells by confocal microscopy. Transient transfection resulted in varying po
Publikováno v:
Computational Biology and Chemistry. 75:120-130
Histone deacetylases (HDACs) play a significant role in the epigenetic mechanism by catalyzing deacetylation of lysine on histone in both animals and plants. HDACs involved in growth, development and response to stresses in plants. Arabidopsis thalia
Autor:
Zhongliang, Jiang, Yanhao, Lai, Jill M, Beaver, Pawlos S, Tsegay, Ming-Lang, Zhao, Julie K, Horton, Marco, Zamora, Hayley L, Rein, Frank, Miralles, Mohammad, Shaver, Joshua D, Hutcheson, Irina, Agoulnik, Samuel H, Wilson, Yuan, Liu
Publikováno v:
Cells
DNA damage and base excision repair (BER) are actively involved in the modulation of DNA methylation and demethylation. However, the underlying molecular mechanisms remain unclear. In this study, we seek to understand the mechanisms by exploring the
Autor:
Ming-Lang Zhao, Rachel Krasich, William C. Copeland, Matthew J. Longley, Donna F. Stefanick, Cristina A. Nadalutti, Rajendra Prasad, Agnes K. Janoshazi, Natalie R. Gassman, Julie K. Horton, Da-Peng Dai, Melike Çağlayan, Jack D. Griffith, Samuel H. Wilson
Publikováno v:
DNA Repair. 60:77-88
Mitochondrial genome integrity is fundamental to mammalian cell viability. Since mitochondrial DNA is constantly under attack from oxygen radicals released during ATP production, DNA repair is vital in removing oxidatively generated lesions in mitoch
Autor:
Ming-Lang Zhao, C. Jeff Tucker, Agnes K. Janoshazi, Rajendra Prasad, Erica L. Scappini, Julie K. Horton, Samuel H. Wilson
Publikováno v:
DNA Repair (Amst)
Fluorescently-tagged repair proteins have been widely used to probe recruitment to micro-irradiation-induced nuclear DNA damage in living cells. Here, we quantify APE1 dynamics after micro-irradiation. Markers of DNA damage are characterized and UV-A
Autor:
Donna F. Stefanick, Samuel H. Wilson, Julie K. Horton, Melike Çağlayan, Ming-Lang Zhao, Agnes K. Janoshazi, Rajendra Prasad, Natalie R. Gassman
Publikováno v:
DNA Repair (Amst)
Aprataxin (APTX) is a DNA-adenylate hydrolase that removes 5′-AMP blocking groups from abortive ligation repair intermediates. XRCC1, a multi-domain protein without catalytic activity, interacts with a number of known repair proteins including APTX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab4dc228c6b6a1ba952d61145a5dfed
https://europepmc.org/articles/PMC9295255/
https://europepmc.org/articles/PMC9295255/