Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ming Kun Lu"'
Ziprasidone triggers inflammasome signaling via PI3K-Akt-mTOR pathway to promote atrial fibrillation
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116649- (2024)
Background: Second-generation antipsychotics increase the risk of atrial fibrillation. This study explores whether the atypical antipsychotic ziprasidone triggers inflammasome signaling, leading to atrial arrhythmia. Methods: Electromechanical and ph
Externí odkaz:
https://doaj.org/article/c823d723a06046f4ab69c8d06673d4ef
Autor:
Xin-Yu Wang, Jin-Jia Lin, Ming-Kun Lu, Fong-Lin Jang, Huai-Hsuan Tseng, Po-See Chen, Po-Fan Chen, Wei-Hung Chang, Chih-Chun Huang, Ke-Ming Lu, Hung-Pin Tan, Sheng-Hsiang Lin
Publikováno v:
npj Schizophrenia, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract In support of the neurodevelopmental model of schizophrenia, minor physical anomalies (MPAs) have been suggested as biomarkers and potential pathophysiological significance for schizophrenia. However, an integrated, clinically useful tool th
Externí odkaz:
https://doaj.org/article/bd020bc31bc04e4bb08637f9fa903d0b
Publikováno v:
npj Schizophrenia, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Early-onset schizophrenia (EOS) may have stronger familial aggregation and a more severe outcome than adult-onset schizophrenia (AOS). MicroRNA (miRNA) takes on dual roles as a genetic and epigenetic modulator, which may mediate the influenc
Externí odkaz:
https://doaj.org/article/af5f35c8f9da41ce8df26dfab4c34c08
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 976 (2022)
Background: Atypical antipsychotics increase the risk of atrial arrhythmias and sudden cardiac death. This study investigated whether ziprasidone, a second-generation antipsychotic, affected intracellular Ca2+ and Na+ regulation and oxidative stress,
Externí odkaz:
https://doaj.org/article/af66113509904ed690af421a31c3c09c
Publikováno v:
Synlett. 31:2049-2053
A visible-light-induced and iron-catalyzed oxidative radical addition/cyclization cascade reaction of N-(o-cyanoaryl)acrylamides with dimethyl sulfoxide has been developed. The method exhibits a wide substrate scope and an excellent functional-group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::082532fa6dd7f2bb965343d9ca50a560
https://doi.org/10.1055/s-0039-1691574
https://doi.org/10.1055/s-0039-1691574
Autor:
Sheng Hsiang Lin, Hung Pin Tan, Jin Jia Lin, Jia Yun Liu, Ming Kun Lu, Han Yu Chen, Fong Lin Jang
Publikováno v:
International Journal of Medical Sciences
Several studies have been suggested that immunity plays a part in neurodevelopment and schizophrenia pathogenesis. Early age of onset in schizophrenia is associated with genetic factors which affect neurodevelopment. This study aims to identify immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d5c91ccf653a259abd867b8f603e04
http://europepmc.org/articles/PMC6990880
http://europepmc.org/articles/PMC6990880
Autor:
Xin-Yu Wang, Jin-Jia Lin, Ming-Kun Lu, Fong-Lin Jang, Huai-Hsuan Tseng, Po-See Chen, Po-Fan Chen, Wei-Hung Chang, Chih-Chun Huang, Ke-Ming Lu, Hung-Pin Tan, Sheng-Hsiang Lin
Publikováno v:
Schizophrenia (Heidelberg, Germany). 8(1)
In support of the neurodevelopmental model of schizophrenia, minor physical anomalies (MPAs) have been suggested as biomarkers and potential pathophysiological significance for schizophrenia. However, an integrated, clinically useful tool that used q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b837715e8c2fc6d96449c7f1742b27c
https://pubmed.ncbi.nlm.nih.gov/35210439
https://pubmed.ncbi.nlm.nih.gov/35210439
Publikováno v:
NPJ Schizophrenia
npj Schizophrenia, Vol 7, Iss 1, Pp 1-9 (2021)
npj Schizophrenia, Vol 7, Iss 1, Pp 1-9 (2021)
Early-onset schizophrenia (EOS) may have stronger familial aggregation and a more severe outcome than adult-onset schizophrenia (AOS). MicroRNA (miRNA) takes on dual roles as a genetic and epigenetic modulator, which may mediate the influence of gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3338c37e09209c9bd33ca91a2bcd71e1
https://doi.org/10.1038/s41537-021-00164-1
https://doi.org/10.1038/s41537-021-00164-1
Autor:
Hung-Pin Tan, Fong-Lin Jang, Shu-Ting Gan, Sheng Hsiang Lin, Bao-Yu Chen, Ming-Kun Lu, Jin-Jia Lin, I-Ning Tsai
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 8, Iss 9, p 1443 (2019)
Volume 8
Issue 9
Journal of Clinical Medicine, Vol 8, Iss 9, p 1443 (2019)
Volume 8
Issue 9
Age at onset is one of the most important clinical features of schizophrenia that could indicate greater genetic loadings. Neurological soft signs (NSS) are considered as a potential endophenotype for schizophrenia. However, the association between N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d137e4797f5504ed3374ede76f7b15
http://europepmc.org/articles/PMC6781040
http://europepmc.org/articles/PMC6781040
Autor:
Ming Chyi Huang, Hsi-Chung Chen, Ming Kun Lu, Yi Hang Chiu, Yin Chieh Lai, Winston W. Shen, Po-Hsiu Kuo, Ru Band Lu
Publikováno v:
Journal of Psychosomatic Research. 76:61-67
Sleep disturbances are frequently observed in major depressive (MDD) and bipolar disorder (BD). This study reported sleep profiles of patients and their relatives versus controls, and examined the familiality of sleep features in mood disorder famili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9df40a655dab819dd8342803f33d30
https://doi.org/10.1016/j.jpsychores.2013.10.020
https://doi.org/10.1016/j.jpsychores.2013.10.020