Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ming Keat Sng"'
Autor:
Pazhanichamy Kalailingam, Hui Bing Tan, Neeraj Jain, Ming Keat Sng, Jeremy Soon Kiat Chan, Nguan Soon Tan, Thirumaran Thanabalu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Neural-Wiskott Aldrich Syndrome Protein (N-WASP) is expressed ubiquitously and regulates actin cytoskeleton remodeling. In order to characterize the role of N-WASP in epidermal homeostasis and cutaneous biology, we generated conditional N-WA
Externí odkaz:
https://doaj.org/article/fc361caafd504099aa1586a2013021c0
Autor:
Ziqiang Teo, Jeremy Soon Kiat Chan, Han Chung Chong, Ming Keat Sng, Chee Chong Choo, Glendon Zhi Ming Phua, Daniel Jin Rong Teo, Pengcheng Zhu, Cleo Choong, Marcus Thien Chong Wong, Nguan Soon Tan
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract In adult skin wounds, collagen expression rapidly re-establishes the skin barrier, although the resultant scar is aesthetically and functionally inferior to unwounded tissue. Although TGFβ signaling and fibroblasts are known to be responsib
Externí odkaz:
https://doaj.org/article/7887f24654604d11834355e7bd5e1492
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5115 (2019)
Non-alcoholic fatty liver disease (NAFLD) can progress from steatosis to non-alcoholic steatohepatitis (NASH) characterized by liver inflammation, possibly leading to cirrhosis and hepatocellular carcinoma (HCC). Mice with impaired macrophage activat
Externí odkaz:
https://doaj.org/article/dd22287dc4a64e2fb99c1341300f5832
Autor:
Yin Hao Lee, Nguan Soon Tan, Hong Sheng Cheng, Zun Siong Low, Jeremy Soon Kiat Chan, Ming Keat Sng, Benjamin Jia Juin Leong, Walter Wahli, Eddie Han Pin Tan, Damien Chua, Mark Wei Yi Tan, Mintu Pal, Xiaomeng Wang, Yun Sheng Yip
Publikováno v:
Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, In press, ⟨10.1038/s41418-020-0535-y⟩
Cell Death Differ
Cell Death and Differentiation, Nature Publishing Group, In press, ⟨10.1038/s41418-020-0535-y⟩
Cell Death Differ
The incidence of nonmelanoma skin cancer (NMSC) has been increasing worldwide. Most studies have highlighted the importance of cancer-associated fibroblasts (CAFs) in NMSC progression. However much less is known about the communication between normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b79431bc8658ad77b9e96b23a36e31
https://hdl.handle.net/10356/144773
https://hdl.handle.net/10356/144773
Autor:
Ming Keat Sng
The skin is the largest organ in the body and is made up of mainly the epidermis and dermis. The skin functions as a natural barrier against external stimuli, dehydration and injury. Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) is one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae1e423803e29543d6112227c4d1a03
https://doi.org/10.32657/10356/66431
https://doi.org/10.32657/10356/66431
Autor:
Chek Kun Tan, Jeremy Soon Kiat Chan, Ming Keat Sng, Ivan Shun Bo How, Jiapeng Chen, Nguan Soon Tan, Walter Wahli, Eddie Han Pin Tan
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2018, ⟨10.1038/s41388-017-0109-8⟩
Oncogene, . (2018)
Oncogene, vol. 37, no. 15, pp. 2067-2078
Oncogene, Nature Publishing Group, 2018, ⟨10.1038/s41388-017-0109-8⟩
Oncogene, . (2018)
Oncogene, vol. 37, no. 15, pp. 2067-2078
Tumor stroma has an active role in the initiation, growth, and propagation of many tumor types by secreting growth factors and modulating redox status of the microenvironment. Although PPARβ/δ in fibroblasts was shown to modulate oxidative stress i
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 20
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5115 (2019)
International Journal of Molecular Sciences 20 (20), 5115. (2019)
International Journal of Molecular Sciences, MDPI, 2019, 20 (20), pp.5115. ⟨10.3390/ijms20205115⟩
Volume 20
Issue 20
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5115 (2019)
International Journal of Molecular Sciences 20 (20), 5115. (2019)
International Journal of Molecular Sciences, MDPI, 2019, 20 (20), pp.5115. ⟨10.3390/ijms20205115⟩
Non-alcoholic fatty liver disease (NAFLD) can progress from steatosis to non-alcoholic steatohepatitis (NASH) characterized by liver inflammation, possibly leading to cirrhosis and hepatocellular carcinoma (HCC). Mice with impaired macrophage activat
Autor:
Ya Lin Tnay, Terri Phua, Mintu Pal, Shunsuke Chiba, Ming Keat Sng, Jia Peng Chen, Jonathan Wei Kiat Wee, Jeremy Soon Kiat Chan, Benny Meng Kiat Tong, Walter Wahli, Eddie Han Pin Tan, Nguan Soon Tan, Ziqiang Teo, Nikki Jun Ning Koh, Xuan Rui Ng, Xiaomeng Wang, Pengcheng Zhu, Chek Kun Tan
Publikováno v:
Cell Discovery
Cell Discovery, 2018, 4, ⟨10.1038/s41421-018-0014-5⟩
Cell Discovery, Vol 4, Iss 1, Pp 1-16 (2018)
Cell Discovery (4), . (2018)
Cell discovery, vol. 4, pp. 15
Cell Discovery, 2018, 4, ⟨10.1038/s41421-018-0014-5⟩
Cell Discovery, Vol 4, Iss 1, Pp 1-16 (2018)
Cell Discovery (4), . (2018)
Cell discovery, vol. 4, pp. 15
Connective tissue diseases of the skin are characterized by excessive collagen deposition in the skin and internal organs. Fibroblasts play a pivotal role in the clinical presentation of these conditions. Nuclear receptor peroxisome-proliferator acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aeba379b0856a59b339eea783f2354f
https://hal.inrae.fr/hal-02628817/document
https://hal.inrae.fr/hal-02628817/document
Autor:
Yinliang Li, Ming Keat Sng, Pengcheng Zhu, Chek Kun Tan, Nguan Soon Tan, Terri Phua, Eddie Han Pin Tan, Dickson Shao Liang Chee, Velmurugesan Arulampalam, Jonathan Wei Kiat Wee, Jeremy Soon Kiat Chan, Ziqiang Teo, Maegan Miang Kee Lim
Publikováno v:
Scientific Reports
Many gastrointestinal diseases exhibit a protracted and aggravated inflammatory response that can lead to hypercytokinaemia, culminating in extensive tissue damage. Recently, angiopoietin-like 4 (ANGPTL4) has been implicated in many inflammation-asso
Autor:
Zhen Wei Tan, Jeremy Soon Kiat Chan, Ziqiang Teo, Justin Yin Hao Lee, Pengcheng Zhu, Terri Phua, Nguan Soon Tan, Luchun Li, Ming Keat Sng, Maegan Miang Kee Lim, Yinliang Li
Publikováno v:
Oncogene
Metastatic cancer cells acquire energy-intensive processes including increased invasiveness and chemoresistance. However, how the energy demand is met and the molecular drivers that coordinate an increase in cellular metabolic activity to drive epith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60106c469edb604f0c56b46002dffdf
https://hdl.handle.net/10356/89157
https://hdl.handle.net/10356/89157