Zobrazeno 1 - 10
of 284
pro vyhledávání: '"Ming Jang Chiu"'
Publikováno v:
Journal of Epidemiology, Vol 32, Iss 11, Pp 502-509 (2022)
Background: Screening or diagnosis for the elderly with dementia in rural regions might be delayed and underestimated due to limited utilization of healthcare resources. This study aimed to evaluate the disparities of prevalence and risk factors of m
Externí odkaz:
https://doaj.org/article/c2097e35238b4510bcb0a4d30d19757d
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Amyloid plaques and tau tangles are pathological hallmarks of Alzheimer’s disease (AD). Parkinson’s disease (PD) results from the accumulation of α-synuclein. TAR DNA-binding protein (TDP-43) and total tau protein (T-Tau) play roles in
Externí odkaz:
https://doaj.org/article/ba541146059349ae88b24127a33a729a
Autor:
Hui Jing Yu, Samuel P. Dickson, Pei-Ning Wang, Ming-Jang Chiu, Chin-Chang Huang, Chiung-Chih Chang, Hope Liu, Suzanne B. Hendrix, Jean-Cosme Dodart, Ajay Verma, Chang Yi Wang, Jeffrey Cummings
Publikováno v:
EBioMedicine, Vol 94, Iss , Pp 104665- (2023)
Summary: Background: Anti-amyloid vaccines may offer a convenient, affordable, and accessible means of preventing and treating Alzheimer's disease. UB-311 is an anti–amyloid-β active immunotherapeutic vaccine shown to be well-tolerated and to have
Externí odkaz:
https://doaj.org/article/e0d10c1151da41e3866df1f7753243bb
Autor:
Ta-Fu Chen, Sheng-Han Lee, Wan-Ru Zheng, Ching-Chou Hsu, Kuan-Hung Cho, Li-Wei Kuo, Charles C.-K. Chou, Ming-Jang Chiu, Boon Lead Tee, Tsun-Jen Cheng
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Air pollution, especially fine particulate matter (PM), can cause brain damage, cognitive decline, and an increased risk of neurodegenerative disease, especially alzheimer’s disease (AD). Typical pathological findings of amyloid
Externí odkaz:
https://doaj.org/article/b951a6eb4c8841b4839eda24332e9cb2
Autor:
Ming-Chyi Pai, Chau-Chung Wu, Yi-Chou Hou, Jiann-Shing Jeng, Sung-Chun Tang, Wei-Che Lin, Cheng-Hsien Lu, Ming-Jang Chiu, Ta-Fu Chen, Sui-Hing Yan, Chaur-Jong Hu, Shieh-Yueh Yang
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Subjects with comorbidities are at risk for neurodegeneration. There is a lack of a direct relationship between comorbidities and neurodegeneration. In this study, immunomagnetic reduction (IMR) assays were utilized to assay plasma Aβ1–42
Externí odkaz:
https://doaj.org/article/cc74d06a16f94954a0841daf380571fd
Publikováno v:
Journal of the Formosan Medical Association, Vol 119, Iss 12, Pp 1862-1870 (2020)
Background/Purpose: Post-stroke dysphagia is a frequent complication. Although most patients with dysphagia recover after the acute phase, some patients require long-term enteral feeding, either through a nasogastric (NG) or gastrostomy tube; the eff
Externí odkaz:
https://doaj.org/article/a49da1343a2d4748af5e263d4d67af90
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2020)
Abstract Background Optimization of vascular risk factor control is emerging as an alternative approach to improve cognitive outcomes in Alzheimer’s disease, although its efficacy is still under debate. We aimed to investigate the contribution of v
Externí odkaz:
https://doaj.org/article/76ff4e6c1d8841a89fac248c1e31dd28
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 10, Iss 1, Pp 46-55 (2020)
Introduction: Blood biomarkers of Alzheimer’s disease (AD) have attracted much attention of researchers in recent years. In clinical studies, repeated freeze/thaw cycles often occur and may influence the stability of biomarkers. This study aims to
Externí odkaz:
https://doaj.org/article/a1dfb905ac3c40adbfb55c75bca8633f
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 9, Iss 1, Pp 77-86 (2019)
Background: The stability of Alzheimer’s disease (AD) biomarkers in plasma, measured by immunomagnetic reduction (IMR) after long-term storage at –80°C, has not been established before. Method: Ninety-nine human plasma samples from 53 normal con
Externí odkaz:
https://doaj.org/article/32e55535cc0c471aaa05c470f965f362
Integrated 18F-T807 Tau PET, Structural MRI, and Plasma Tau in Tauopathy Neurodegenerative Disorders
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Background and Objective: Tau-specific positron emission topography (PET) imaging enables in vivo assessment of Alzheimer's disease (AD). We aimed to investigate its performance in combination with plasma tau levels in patients with non-AD tauopathy.
Externí odkaz:
https://doaj.org/article/d79f6e1513b249fcbc678d0b0caade65