Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Ming Der Perng"'
Publikováno v:
Endocrines, Vol 3, Iss 2, Pp 214-222 (2022)
Self-monitoring of blood glucose (SMBG) is common in patients with diabetes. The aim of this study was to explore how frequency/behavior of SMBG affect glucose control in patients with type 2 diabetes. This cross-sectional study was conducted at a re
Externí odkaz:
https://doaj.org/article/cdff708ea5a7407a97c09974037c6508
Autor:
Ching Lu, Chao-Lun Lai, Chih-Man Yang, Karen Chia-Wen Liao, Chie-Shung Kao, Tien-Chu Chang, Ming-Der Perng
Publikováno v:
Medicina, Vol 58, Iss 12, p 1748 (2022)
Background and Objectives: The aim of this study was to investigate the relationships between obesity-related factors including body mass index (BMI), diabetes or prediabetes, hyperlipidemia, fasting plasma glucose, fasting plasma insulin, homeostasi
Externí odkaz:
https://doaj.org/article/47f43fbb00ef46d6a6d0c6a8d6a10d60
Autor:
Ni-Hsuan Lin, Angela Goh, Shyh-Horng Lin, Kai-An Chuang, Chih-Hsuan Chang, Ming-Han Li, Chu-Hsun Lu, Wen-Yin Chen, Pei-Hsuan Wei, I-Hong Pan, Ming-Der Perng, Shu-Fang Wen
Publikováno v:
Journal of Alzheimer's Disease Reports. 7:51-76
Background: Alzheimer’s disease (AD) is a multifactorial disorder characterized by cognitive decline. Current available therapeutics for AD have limited clinical benefit. Therefore, preventive therapies for interrupting the development of AD are cr
Autor:
So-Hyun Lee, Tai-Seung Nam, Kun-Hee Kim, Jin Hee Kim, Woong Yoon, Suk-Hee Heo, Min Jung Kim, Boo Ahn Shin, Ming-Der Perng, Hyon E. Choy, Jihoon Jo, Myeong-Kyu Kim, Seok-Yong Choi
Publikováno v:
BMC Neurology, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Alexander disease (AxD) is an astrogliopathy that predominantly affects the white matter of the central nervous system (CNS), and is caused by a mutation in the gene encoding the glial fibrillary acidic protein (GFAP), an intermed
Externí odkaz:
https://doaj.org/article/b59d8d53adf148b0bae0da01012b67a5
Autor:
Rachel A Battaglia, Adriana S Beltran, Samed Delic, Raluca Dumitru, Jasmine A Robinson, Parijat Kabiraj, Laura E Herring, Victoria J Madden, Namritha Ravinder, Erik Willems, Rhonda A Newman, Roy A Quinlan, James E Goldman, Ming-Der Perng, Masaki Inagaki, Natasha T Snider
Publikováno v:
eLife, Vol 8 (2019)
Alexander disease (AxD) is a fatal neurodegenerative disorder caused by mutations in glial fibrillary acidic protein (GFAP), which supports the structural integrity of astrocytes. Over 70 GFAP missense mutations cause AxD, but the mechanism linking d
Externí odkaz:
https://doaj.org/article/1a944b07b95f440191c0e5f0e38980a8
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180694 (2017)
Alexander disease (AxD) is a neurodegenerative disease caused by heterozygous mutations in the GFAP gene, which encodes the major intermediate filament protein of astrocytes. This disease is characterized by the accumulation of cytoplasmic protein ag
Externí odkaz:
https://doaj.org/article/6904c79a477a4df28429d437f64e1c85
Publikováno v:
Molecular biology of the cell. 33(8)
Alexander disease is a primary genetic disorder of astrocytes caused by dominant mutations in the gene encoding glial fibrillary acidic protein (GFAP). How single-amino-acid changes can lead to cytoskeletal catastrophe and brain degeneration remains
Autor:
Ming-Hsiang Chen, Muhammed Muhsin Varikkodan, Ting-Hui Lin, Chien-Min Chiang, Indah Permata Sari, Ming-Der Perng, Tzong-Yuan Wu
Publikováno v:
Processes; Volume 10; Issue 5; Pages: 895
Classical swine fever virus (CSFV) and porcine circovirus type 2 (PCV2) have caused severe diseases in swine populations worldwide. Here, a polycistronic baculovirus vector was developed to express a bivalent vaccine, consisting of the CSFV-E2 and PC
Autor:
Amy Waldman, Ming Der Perng, Marzena Walkiewicz, Michael Brenner, Omar Sherbini, Guy Helman, Adeline Vanderver, Cas Simons, Sunetra Sase, Ling Zhao, Bret C. Haake, Zachary Cross, Sarah Woidill, Asako Takanohashi, Yangzhu Du, Ali Fatemi, Tracy L. Hagemann, Albee Messing
Publikováno v:
Hum Mutat
Alexander disease results from gain of function mutations in the gene encoding glial fibrillary acidic protein (GFAP), an intermediate filament protein expressed in astrocytes. At least eight GFAP isoforms have been described, however, the predominan
Autor:
Berit Powers, Albee Messing, Ahmed F. Mohamed, Tracy L. Hagemann, Curt Mazur, Robert F. Berman, Seth C. Hannah, Ni-Hsuan Lin, Katerina L. Dague, Mel B. Feany, Abby L. Olsen, Frank Rigo, Ming-Der Perng, Gemma Bachmann
Publikováno v:
Sci Transl Med
Science translational medicine, vol 13, iss 620
Science translational medicine, vol 13, iss 620
Alexander disease (AxD) is a devastating leukodystrophy caused by gain-of-function mutations in GFAP, and the only available treatments are supportive. Recent advances in antisense oligonucleotide (ASO) therapy have demonstrated that transcript targe