Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ming Dauh Wang"'
Autor:
Alan R. Shuldiner, Chalothorn Dan, Sarah Sharman Moser, Morton Lori C, Ming-Dauh Wang, Gabriel Chodick, Yan G. Ni, Ophira Salomon, Jessica J. Jalbert
Publikováno v:
Thrombosis and Haemostasis. 122:808-817
The objective of this study was to assess the relationship between factor XI (FXI) deficiency and the risks of bleeding and cardiovascular (CV) events. We conducted a retrospective cohort study using data from Maccabi Healthcare Services (MHS). We id
Autor:
Günsel Kutluk, Sevgi Bilgic Eltan, Camille Lake, Samuel D. Chauvin, Reha Artan, Dilara Fatma Kocacık Uygun, Camille Alba, Erdem Topal, Figen Özçay, Foo Cheung, Ali Islek, Yu Zhang, Michael J. Lenardo, Poorani Subramanian, Elif Karakoc-Aydiner, Yan G. Ni, Yasmine Belkaid, Buket Dalgic, Richard Apps, Clifton L. Dalgard, Rabia Ergelen, Kishor Devalaraja-Narashimha, Oya Balci Sezer, Merve Selcuk, Ivan Vujkovic-Cvijin, Deniz Ertem, Ming-Dauh Wang, Giovanna Fantoni, Engin Tutar, Nurhan Kasap, Bilge Şahin Akkelle, Ayşen Bingöl, Safa Baris, Gamze Akgun, Ismail Ogulur, Roderick H. J. Houwen, Andrew L. Snow, Brian Sellers, Cigdem Ataizi Celikel, Ersin Sayar, Olivier Harari, Ahmet Ozen, John S. Tsang, Sinan Sari, Şükrü Nail Güner
Publikováno v:
Nature immunology
Ozcay, Figen/0000-0002-5214-516X; celikel, cigdem/0000-0002-9360-8116 WOS: 000604865800004 PubMed: 33398182 CHAPLE disease is a lethal syndrome caused by genetic loss of the complement regulatory protein CD55. Lenardo, Ozen and their colleagues repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18248f1a632f11f433492a76826bdc14
https://doi.org/10.1038/s41590-020-00830-z
https://doi.org/10.1038/s41590-020-00830-z
Autor:
Ming-Dauh Wang, Yimin Cui, David S. Small, Jian Jun Jin, Yan Liang, Jeffrey G. Suico, Ping Xin, Ellen A. Cannady, Xia Zhao
Publikováno v:
International Journal of Pharmacokinetics. 3:69-80
Aim: Evaluate steady-state pharmacokinetics and potential interactions between select statins and evacetrapib. Patients & methods: This open-label, two-part study included 62 healthy native Chinese subjects. Part 1 evaluated pharmacokinetics and phar
Autor:
Steven E. Nissen, Giacomo Ruotolo, Steven J. Adelman, John P. Kane, H. Bryan Brewer, Kathryn A. Krueger, Stephen J. Nicholls, Daniel J. Rader, Ming Dauh Wang
Publikováno v:
Journal of the American College of Cardiology. 66(20):2201-2210
Background Potent cholesteryl ester transfer protein (CETP) inhibitors have been shown to substantially increase high-density lipoprotein cholesterol (HDL-C) and apolipoprotein A-I levels as monotherapy and combined with statins. However, data on the
Autor:
Ming-Dauh Wang, Jonathan Weyne, Yan G. Ni, Cong Huang, Andrew J Rankin, Olivier Harari, Kishor Devalaraja-Narashimha, Morton Lori C, Umesh Chaudhari, Srinivasa Prasad
Publikováno v:
Blood. 134:2278-2278
INTRODUCTION: Blockade of complement factor C5 has demonstrated benefit in paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, generalized myasthenia gravis and neuromyelitis optica. We have completed a Phase I study of pozelimab
The trimmed mean is a method of dealing with patient dropout in clinical trials that considers early discontinuation of treatment a bad outcome rather than leading to missing data. The present investigation is the first comprehensive assessment of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2623b5eb952ac7bebc2bfc372ab2ecb9
http://hdl.handle.net/1942/26190
http://hdl.handle.net/1942/26190
Autor:
Ming Dauh Wang, Stephen J. Nicholls, Ellen A. Cannady, Stuart Friedrich, Jessica Rehmel, Jeffrey G. Suico, Kathryn A. Krueger
Publikováno v:
British Journal of Clinical Pharmacology
Aims Evacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor under development for reducing cardiovascular events in patients with high risk vascular disease. CETP inhibitors are likely to be utilized as ‘add-on’ therapy to statins i
Autor:
Ming-Dauh Wang, Alan Y. Chiang
Publikováno v:
Statistics in Biopharmaceutical Research. 7:66-75
Adverse effects of pharmaceuticals on electrocardiograms (ECGs) are one of the most critical drug safety concerns facing drug development companies today. It is recognized that a better understanding of the interrelationship between preclinical measu
Autor:
Paul Frewer, Erik Pulkstenis, Jianliang Zhang, Ming-Dauh Wang, Paul Metcalfe, Aaron Dane, Kaushik Patra
Publikováno v:
Clinical Trial Optimization Using R ISBN: 9781315120836
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e06c500eb249990f71e53e7ff8da9c80
https://doi.org/10.1201/9781315120836-4
https://doi.org/10.1201/9781315120836-4
Autor:
Giacomo Ruotolo, Stuart Friedrich, Ellen A. Cannady, Kathryn A. Krueger, Jeffrey G. Suico, Christopher S Konkoy, Ming-Dauh Wang
Publikováno v:
The Journal of Pharmacy and Pharmacology
Objectives We investigated the safety, tolerability, pharmacokinetics and pharmacodynamics of evacetrapib. Methods Healthy volunteers received multiple daily doses of evacetrapib (10–600 mg) administered for up to 15 days in a placebo-controlled st