Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Ming Chieh Ma"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Chronic rhinosinusitis (CRS) can be traditionally classified as CRSwNP [with nasal polyps (NPs)] and CRSsNP (without NPs) based on the clinical phenotypes but recently suggested to be classified by the endotypes. We have identified overexpre
Externí odkaz:
https://doaj.org/article/f65fae0ac51d4472a8112178f9c3c9bb
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 9, Iss 5, p 111 (2024)
The purpose of this study is to clarify the role of IL-33 in the immune response to angiostrongyliasis, especially in terms of antibody production and isotype switching. In our experiment, C57BL/6 mice were each infected with 35 infectious larvae and
Externí odkaz:
https://doaj.org/article/27b4bd0c72e2430dab8c71013f7cc9aa
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1899 (2022)
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complicated inflammatory disease, and the underlying mechanism remains unclear. While some reactive oxygen/nitrogen species-related gene products are reported to participate in CRSwNP, a systemic
Externí odkaz:
https://doaj.org/article/e5e83906470444dcb64ea10c5eeee497
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 361 (2022)
Hydrogen sulfide (H2S) was the third gasotransmitter to be recognized as a cytoprotectant. A recent study demonstrated that exogenous supplementation of H2S ameliorates functional insufficiency in chronic kidney disease (CKD). However, how the H2S sy
Externí odkaz:
https://doaj.org/article/aaf1101998c94508a68727397ece03a1
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6204 (2021)
Inflammation worsens oxalate nephropathy by exacerbating tubular damage. The transient receptor potential vanilloid 1 (TRPV1) channel is present in kidney and has a polymodal sensing ability. Here, we tested whether TRPV1 plays a role in hyperoxaluri
Externí odkaz:
https://doaj.org/article/51e60bbc22dd4590b834eecaf945bcf2
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 936 (2021)
The accumulation of the uremic toxin indoxyl sulfate (IS) induces target organ damage in chronic kidney disease (CKD) patients, and causes complications including cardiovascular diseases, renal osteodystrophy, muscle wasting, and anemia. IS stimulate
Externí odkaz:
https://doaj.org/article/907486df101f4c71a867b1ae0a428692
Autor:
Jiun Hsu, Chih-Hsien Wang, Shu-Chien Huang, Yung-Wei Chen, Shengpin Yu, Juey-Jen Hwang, Jou-Wei Lin, Ming-Chieh Ma, Yih-Sharng Chen
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221039 (2019)
Ischemic neuron loss contributes to brain dysfunction in patients with cardiac arrest (CA). Histidine-tryptophan-ketoglutarate (HTK) solution is a preservative used during organ transplantation. We tested the potential of HTK to protect neurons from
Externí odkaz:
https://doaj.org/article/54f62dc6a79b47e0a50d6f8d8e55380b
Autor:
Tong-Hong Cheng, Ming-Chieh Ma, Min-Tser Liao, Cai-Mei Zheng, Kuo-Cheng Lu, Chun-Hou Liao, Yi-Chou Hou, Wen-Chih Liu, Chien-Lin Lu
Publikováno v:
Toxins, Vol 12, Iss 11, p 684 (2020)
Indoxyl sulfate (IS), a uremic toxin, causes chronic kidney disease (CKD) progression via its tubulotoxicity. After cellular uptake, IS directly induces apoptotic and necrotic cell death of tubular cells. Additionally, IS increases oxidative stress a
Externí odkaz:
https://doaj.org/article/7ce08f4d30fc4112a65cf073b8569a0c
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6212 (2020)
Indoxyl sulfate (IS) is accumulated during severe renal insufficiency and known for its nephrotoxic properties. Transient receptor potential vanilloid 1 (TRPV1) is present in the kidney and acts as a renal sensor. However, the mechanism underlying IS
Externí odkaz:
https://doaj.org/article/d297f3acf12c4532b10f0794daa9967c
Publikováno v:
American Journal of Physiology-Renal Physiology. 320:F799-F813
Ionotropic N-methyl-d-aspartate receptors (NMDARs) are not only present in the nervous system but also expressed in the kidney. Overstimulation of renal NMDARs leads to oxidative stress via the signal pathway of calcium/protein kinase C/NADPH oxidase