Výsledky vyhledávání - "Ming Cheng Wei"

Abstract 818: Preclinical studies of the cabazitaxel nanoformulation MPB-1734 support therapeutic application in chemo-resistant solid tumors and synergistic benefit in combination with immune checkpoint inhibitor

Autor: Yuan Hung Hsu, Chih-Lung Chen, Jhih-Yun Jian, Ming-Cheng Wei, Wen-Yuan Hsieh, Chia-Wen Huang, Yung-Chu Chen, Tzu-Hsin Liao, Shian-Jy Wang

Publikováno v: Cancer Research. 83:818-818

Background: Cabazitaxel (CBZ) is a second-generation taxane that has the potential to overcome taxane-resistance due to the low affinity for the P-glycoprotein efflux pump. However, with the high systemic toxicity such as neutropenia and hypersensiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::984fa5691738192d95fce45c79964e9e
https://doi.org/10.1158/1538-7445.am2023-818

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Osteoporosis and Stress Urinary Incontinence in Women: A National Health Insurance Database Study

Autor: Yu-Hsun Wang, Ying-Hsiang Chou, Chien-Ning Huang, Edy Kornelius, Ming-Cheng Wei, Yi-Sun Yang

Publikováno v: International Journal of Environmental Research and Public Health, Vol 17, Iss 4449, p 4449 (2020)
International Journal of Environmental Research and Public Health
Volume 17
Issue 12

We aimed to determine the influence of osteoporosis and stress urinary incontinence in women. We hypothesized that women with osteoporosis had an increased risk of stress urinary incontinence. This retrospective study used data from the Taiwan Longit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d88179089843b112501f25236cf6ad9
https://www.mdpi.com/1660-4601/17/12/4449

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Akademický článek

Pharmacokinetic analysis of 111 in-labeled liposomal Doxorubicin in murine glioblastoma after blood-brain barrier disruption by focused ultrasound.

Autor: Feng-Yi Yang, Hsin-Ell Wang, Ren-Shyan Liu, Ming-Che Teng, Jia-Je Li, Maggie Lu, Ming-Cheng Wei, Tai-Tong Wong

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e45468 (2012)

The goal of this study was to evaluate the pharmacokinetics of targeted and untargeted (111)In-doxorubicin liposomes after these have been intravenously administrated to tumor-bearing mice in the presence of blood-brain barrier disruption (BBB-D) ind

Externí odkaz: https://doaj.org/article/0ad4eb0c6fb3405a995f002339129b72

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Optimal Initial Blood Pressure in Intensive Care Unit Patients with Non-Traumatic Intracranial Hemorrhage

Autor: Edy Kornelius, Chien-Ning Huang, Jing-Yang Huang, Ming-Cheng Wei, Ying-Hsiang Chou, Yi-Sun Yang

Publikováno v: International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 17, Iss 3436, p 3436 (2020)
Volume 17
Issue 10

Blood pressure (BP) control is crucial for minimizing the risk of mortality and hematoma growth in patients with acute intracranial hemorrhage (ICH). We aimed to determine the optimal BP range associated with improved patient outcomes. From the Medic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244208f95ff65fe318b40f4cc212b679
https://doi.org/10.3390/ijerph17103436

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Hyperthermia-Mediated Local Drug Delivery by a Bubble-Generating Liposomal System for Tumor-Specific Chemotherapy

Autor: Ming Cheng Wei, Shiaw-Pyng Wey, Kun-Ju Lin, Chun Min Liu, Hsiang-Wen Tseng, Hao-Li Liu, Chia Chen Lin, Chih Peng Liu, Hsing-Wen Sung, Ko Jie Chen, Felice Cheng, Er Yuan Chaung

Publikováno v: ACS Nano. 8:5105-5115

As is widely suspected, lysolipid dissociation from liposomes contributes to the intravenous instability of ThermoDox (lysolipid liposomes), thereby impeding its antitumor efficacy. This work evaluates the feasibility of a thermoresponsive bubble-gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d74564d5d3f82874c9fd4e5fae9cace
https://doi.org/10.1021/nn501162x

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Mechanisms of cellular uptake and intracellular trafficking with chitosan/DNA/poly(γ-glutamic acid) complexes as a gene delivery vector

Autor: Ming-Cheng Wei, Shu-Fen Peng, Zi-Xian Liao, Michael T. Tseng, Yi Cheng Ho, Hsing-Wen Sung

Publikováno v: Biomaterials. 32:239-248

Chitosan (CS)-based complexes have been considered as a vector for DNA delivery; nonetheless, their transfection efficiency is relatively low. An approach by incorporating poly(γ-glutamic acid) (γ-PGA) in CS/DNA complexes was developed in our previ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d50c61122f16ede84ed65b05031783
https://doi.org/10.1016/j.biomaterials.2010.08.081

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Effects of the nanostructure of dendrimer/DNA complexes on their endocytosis and gene expression

Autor: Po-Wei Lee, Shu-Fen Peng, Zi-Xian Liao, Hsin-Lung Chen, Chun-Jen Su, Chun-Yu Chen, Hsing-Wen Sung, Ming-Cheng Wei

Publikováno v: Biomaterials. 31:5660-5670

Cationic dendrimers constitute a potential nonviral vector for gene therapy due to their ability of forming electrostatic complexes with DNA (dendriplexes). However, the supramolecular structure of dendriplexes and its impact on the cellular uptake a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93646d5785dccdf51ecfc4d2d3f00fa6
https://doi.org/10.1016/j.biomaterials.2010.03.059

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The use of biodegradable polymeric nanoparticles in combination with a low-pressure gene gun for transdermal DNA delivery

Autor: Hao Jan Lin, Fwu Long Mi, Hsing-Wen Sung, Chun Jen Su, Shu Fen Peng, Ming Cheng Wei, Po Wei Lee, Hsin-Lung Chen

Publikováno v: Biomaterials. 29:742-751

Gold particles have been used as a carrier for transdermal gene delivery, which may cause adverse side effects when accumulated. In this study, biodegradable nanoparticles, composed of chitosan (CS) and poly-gamma-glutamic acid (gamma-PGA), were prep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac52d48ec9a3388958e2365cac3665a8
https://doi.org/10.1016/j.biomaterials.2007.10.034

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Interleukin-4 receptor-targeted liposomal doxorubicin as a model for enhancing cellular uptake and antitumor efficacy in murine colorectal cancer

Autor: Hong-Wen Liu, Chin-Yau Chen, Maggie Lu, Wei-Nan Lian, Chih-Yung Yang, Jeng-Kai Jiang, Chi Hung Lin, Ya-Ching Tsai, Ming-Cheng Wei, Ju-Yu Tseng, Ruey-Hwa Lu, Shu-Ching Liang

Publikováno v: Cancer biologytherapy. 16(11)

Our previous studies showed that colorectal tumor has high interleukin-4 receptor α (IL-4Rα) expression, whereas adjacent normal tissue has low or no IL-4Rα expression. We also observed that human atherosclerotic plaque-specific peptide-1 (AP1) ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad3714642d28a41f4f1e40cd2ad1b0f
https://pubmed.ncbi.nlm.nih.gov/26436767

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A New Approach to Reduce Toxicities and to Improve Bioavailabilities of Platinum-Containing Anti-Cancer Nanodrugs

Autor: Shen-Chuan Lo, Ya-Chin Lo, Ming-Cheng Wei, Chien Ho, Yu-Hsiang Chen, Maggie Lu, Daniel J. Bain, Li Liu, Yuan-Hung Hsu, Qing Ye, Shian-Jy Wang

Publikováno v: Scientific Reports

Platinum (Pt) drugs are the most potent and commonly used anti-cancer chemotherapeutics. Nanoformulation of Pt drugs has the potential to improve the delivery to tumors and reduce toxic side effects. A major challenge for translating nanodrugs to cli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584f7411a7ea1b5c535ab6c980e244e3
https://doi.org/10.1038/srep10881

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