Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Ming C. Hammond"'
Autor:
Zhesen Tan, Chi Ho Chan, Michael Maleska, Bryan Banuelos Jara, Brian K. Lohman, Nathan J. Ricks, Daniel R. Bond, Ming C. Hammond
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1183 (2022)
The Hypr cGAMP signaling pathway was discovered via the function of the riboswitch. In this study, we show the development of a method for affinity capture followed by sequencing to identify non-coding RNA regions that bind nucleotide signals such as
Externí odkaz:
https://doaj.org/article/1cff22fe4f024d8083608754276cfd04
Autor:
Aiming Ren, Xin C. Wang, Colleen A. Kellenberger, Kanagalaghatta R. Rajashankar, Roger A. Jones, Ming C. Hammond, Dinshaw J. Patel
Publikováno v:
Cell Reports, Vol 11, Iss 1, Pp 1-12 (2015)
Cyclic dinucleotides are second messengers that target the adaptor STING and stimulate the innate immune response in mammals. Besides protein receptors, there are bacterial riboswitches that selectively recognize cyclic dinucleotides. We recently dis
Externí odkaz:
https://doaj.org/article/6f80ccb10dd84b85afd667301f28d7cc
Autor:
Elie J. Diner, Dara L. Burdette, Stephen C. Wilson, Kathryn M. Monroe, Colleen A. Kellenberger, Mamoru Hyodo, Yoshihiro Hayakawa, Ming C. Hammond, Russell E. Vance
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1355-1361 (2013)
The presence of foreign DNA in the cytosol of mammalian cells elicits a potent antiviral interferon response. Recently, cytosolic DNA was proposed to induce the synthesis of cyclic GMP-AMP (cGAMP) upon binding to an enzyme called cGAMP synthase (cGAS
Externí odkaz:
https://doaj.org/article/2a539847a7d542709f20c5ca08f20165
Autor:
Rebecca C Lowry, Zachary F Hallberg, Rob Till, Tyler J Simons, Ruth Nottingham, Fiona Want, R Elizabeth Sockett, Ming C Hammond, Carey Lambert
Publikováno v:
PLoS Genetics, Vol 18, Iss 5, p e1010164 (2022)
Bacterial second messengers are important for regulating diverse bacterial lifestyles. Cyclic di-GMP (c-di-GMP) is produced by diguanylate cyclase enzymes, named GGDEF proteins, which are widespread across bacteria. Recently, hybrid promiscuous (Hypr
Externí odkaz:
https://doaj.org/article/0547c364590f4a9aa39c405a5d63c08f
Publikováno v:
Journal of visualized experiments : JoVE. (186)
Fluorogenic RNA aptamers have been applied in live cells to tag and visualize RNAs, report on gene expression, and activate fluorescent biosensors that detect levels of metabolites and signaling molecules. In order to study dynamic changes in each of
Autor:
Nagaraja Mukkayyan, Raymond Poon, Philipp N. Sander, Li-Yin Lai, Zahra Zubair-Nizami, Ming C. Hammond, Som S. Chatterjee
Publikováno v:
ACS Omega. 7:32749-32753
Autor:
Zachary F Hallberg, Chi Ho Chan, Todd A Wright, Philip J Kranzusch, Kevin W Doxzen, James J Park, Daniel R Bond, Ming C Hammond
Publikováno v:
eLife, Vol 8 (2019)
A newfound signaling pathway employs a GGDEF enzyme with unique activity compared to the majority of homologs associated with bacterial cyclic di-GMP signaling. This system provides a rare opportunity to study how signaling proteins natively gain dis
Externí odkaz:
https://doaj.org/article/ef3b900a1173420ba4791918d80a83ac
Autor:
Sudeshna Manna, Michiko Kimoto, Johnny Truong, Praneeth Bommisetti, Ava Peitz, Ichiro Hirao, Ming C. Hammond
Engineered RNAs have applications in diverse fields, from biomedical to environmental. In many cases, folding of the RNA is critical to its function. Here we describe a strategy to improve the folding kinetics of a riboswitch-based fluorescent biosen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed67fb6afa73c7305033e5904a10e86b
https://doi.org/10.26434/chemrxiv-2023-xlth4
https://doi.org/10.26434/chemrxiv-2023-xlth4
Autor:
Bryan Banuelos Jara, Ming C. Hammond
Publikováno v:
Handbook of Chemical Biology of Nucleic Acids ISBN: 9789811613135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::711c7f594d27f32a85f57f24c042cd4b
https://doi.org/10.1007/978-981-16-1313-5_91-1
https://doi.org/10.1007/978-981-16-1313-5_91-1
Publikováno v:
Journal of Visualized Experiments.