Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Ming⁃ming HU"'
Autor:
Chaojun Yan, Jingjing Xiong, Zirui Zhou, Qifang Li, Chuan Gao, Mengyao Zhang, Liya Yu, Jinpeng Li, Ming-Ming Hu, Chen-Song Zhang, Cheguo Cai, Haojian Zhang, Jing Zhang
Publikováno v:
eLife, Vol 12 (2023)
N6-methyladenosine (m6A) methylation of RNA by the methyltransferase complex (MTC), with core components including METTL3–METTL14 heterodimers and Wilms’ tumor 1-associated protein (WTAP), contributes to breast tumorigenesis, but the underlying r
Externí odkaz:
https://doaj.org/article/d8a43705d24e475c9588915e832d39a2
Autor:
Shan Su, Duo Hua, Jin-Peng Li, Xia-Nan Zhang, Lei Bai, Li-Bo Cao, Yi Guo, Ming Zhang, Jia-Zhen Dong, Xiao-Wei Liang, Ke Lan, Ming-Ming Hu, Hong-Bing Shu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract Whether and how innate antiviral response is regulated by humoral metabolism remains enigmatic. We show that viral infection induces progesterone via the hypothalamic-pituitary-adrenal axis in mice. Progesterone induces downstream antiviral
Externí odkaz:
https://doaj.org/article/a7a982087ef54da1a75415abf94a99d1
Autor:
Wenjun Xiong, Xueliang Gao, Tiantian Zhang, Baishan Jiang, Ming-Ming Hu, Xia Bu, Yang Gao, Lin-Zhou Zhang, Bo-Lin Xiao, Chuan He, Yishuang Sun, Haiou Li, Jie Shi, Xiangling Xiao, Bolin Xiang, Conghua Xie, Gang Chen, Haojian Zhang, Wenyi Wei, Gordon J. Freeman, Hong-Bing Shu, Haizhen Wang, Jinfang Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The regulatory mechanisms of PD-L1 posttranslational modifications are not completely understood. Here the authors show that USP8 negatively regulates PD-L1 protein abundance by removing the K63-linked ubiquitination of PD-L1; while USP8 inhibition i
Externí odkaz:
https://doaj.org/article/e769071990584a6aa031c02542686ae3
Autor:
Meng-Yun Li, Zhi-Hong Lin, Ming-Ming Hu, Li-Qing Kang, Xiao-xia Wu, Qi-wei Chen, Xin Kong, Jian Zhang, Hui-Ying Qiu, De-Pei Wu
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-6 (2020)
Abstract Background Mixed phenotype acute leukemia (MPAL) is a rare leukemia and is regarded as a high-risk entity with a poor prognosis. Induction therapy of an acute lymphoblastic leukemia type or hybrid regimen and hematopoietic stem cell transpla
Externí odkaz:
https://doaj.org/article/94106da34ed2401093bcb170a914ec9a
Autor:
Da Zhang, Lin Lu, Hui-Juan Zhu, Yu Xiao, Xian-Lin Han, Shun-Da Du, Hua-Dan Xue, Qing-Xing Liu, Zhao-Hui Zhu, Ming-Ming Hu, Xiao Zhai, Xiao-Ping Xing, Zhao-Lin Lu
Publikováno v:
International Journal of Endocrinology, Vol 2022 (2022)
Objectives. To analyze and summarize the effect of SSA treatment on EAS due to p-NETs (EAS-p-NETs). Methods. Thirteen patients with EAS-p-NETs treated with SSAs at our center or described in the literature were included in this study. Clinical charac
Externí odkaz:
https://doaj.org/article/4af07185acd04753a2f2bd4e3874a349
Autor:
Huan Lian, Jin Wei, Ru Zang, Wen Ye, Qing Yang, Xia-Nan Zhang, Yun-Da Chen, Yu-Zhi Fu, Ming-Ming Hu, Cao-Qi Lei, Wei-Wei Luo, Shu Li, Hong-Bing Shu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
cGAS is an important mediator of antiviral immune responses, but the regulation of its activity is unknown. Here, the authors identify a zinc finger protein, ZCCHC3, that enhances the binding of cGAS to dsDNA and is important for its activation follo
Externí odkaz:
https://doaj.org/article/787e1f46425144ed98d0dc92723cdac6
Publikováno v:
Tongxin xuebao, Vol 38, Pp 34-47 (2017)
In short-range wireless communication system(SWCS)，the complex scenarios make its transmission face the diverse interference，and lower hardware resource leads to its limited anti-interference capability.To achieve the reliable transmission，a fr
Externí odkaz:
https://doaj.org/article/06a2ac78779a43b68a1b943f920ee69f
Autor:
Huan Lian, Jin Wei, Ru Zang, Wen Ye, Qing Yang, Xia-Nan Zhang, Yun-Da Chen, Yu-Zhi Fu, Ming-Ming Hu, Cao-Qi Lei, Wei-Wei Luo, Shu Li, Hong-Bing Shu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/6bbe448f6a6e4e3688bfcad46115a65d
Autor:
Jin Wei, Huan Lian, Wei Guo, Yun-Da Chen, Xia-Nan Zhang, Ru Zang, Li Zhong, Qing Yang, Ming-Ming Hu, Wei-Wei Luo, Hong-Bing Shu, Shu Li
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007336 (2018)
MITA (also called STING) is a central adaptor protein in innate immune response to cytosolic DNA. Cellular trafficking of MITA from the ER to perinuclear microsomes after DNA virus infection is critical for MITA activation and onset of innate antivir
Externí odkaz:
https://doaj.org/article/657fb8dc74d64bec9a985d3c4ead900b
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006648 (2017)
Sensing of viral RNA by RIG-I-like receptors initiates innate antiviral response, which is mediated by the central adaptor VISA. How the RIG-I-VISA-mediated antiviral response is terminated at the late phase of infection is enigmatic. Here we identif
Externí odkaz:
https://doaj.org/article/719b88a94978489b906fd4c23ef6a462