Zobrazeno 1 - 10
of 1 492
pro vyhledávání: '"Ming‐Sound Tsao"'
Autor:
Ellen Yang, MD, FRCPC, Najd Alshamlan, MD, Katrina Hueniken, MSc, Jessica Weiss, MSc, Michael Cabanero, MD, Ming-Sound Tsao, MD, FRCPC
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 7, Pp 100682- (2024)
Introduction: Lepidic growth is considered noninvasive in lung nonmucinous adenocarcinoma, whereas other patterns are invasive. Considerable interobserver variability in assessing “invasion” has been reported. We assessed the utility of cytokerat
Externí odkaz:
https://doaj.org/article/7c10847babb54e9cab8465002c004d7d
Autor:
Mohamed Bourmoum, Nikolina Radulovich, Amit Sharma, Johnny M Tkach, Ming-Sound Tsao, Laurence Pelletier
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0295030 (2024)
Colorectal cancer is the third most common cancer and the second leading cause of cancer-related deaths worldwide. The centrosome is the main microtubule-organizing center in animal cells and centrosome amplification is a hallmark of cancer cells. To
Externí odkaz:
https://doaj.org/article/2ed4175e77cb4cff86ba7f89c0480ecb
Autor:
Kaitlin H. Chen, BSc, Tristan A. Barnes, MD, BS, Janessa Laskin, MD, Parneet Cheema, MD, MBiotech, Geoffrey Liu, MD, MS, Mussawar Iqbal, MD, Jeffrey Rothenstein, MD, Ronald Burkes, MD, Ming-Sound Tsao, MD, Natasha B. Leighl, MD, MMSc
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 1, Pp 100615- (2024)
Introduction: Liquid biopsy is recommended to diagnose molecular resistance to targeted therapy in patients with lung cancer. Nevertheless, not all jurisdictions provide funding and patient access. We report patients’ perceived value of liquid biop
Externí odkaz:
https://doaj.org/article/bb83005dd58b4c3492bec95a48fdc8a9
Autor:
Sally C.M. Lau, MD, MPH, Kirstin Perdrizet, MD, Andrea S. Fung, MD, PhD, Danilo Giffoni M.M. Mata, MD, Jessica Weiss, PhD, Nick Holzapfel, MD, Geoffrey Liu, MD, Penelope A. Bradbury, MD, Frances A. Shepherd, MD, Adrian G. Sacher, MD, MMSc, Harriet Feilotter, MD, Brandon Sheffield, MD, David Hwang, MD, Ming Sound Tsao, MD, Susanna Cheng, MD, Parneet Cheema, MD, Natasha B. Leighl, MD, MMSc
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 10, Pp 100562- (2023)
Introduction: NSCLC with MET exon 14 skipping mutation (METex14) is associated with poor outcomes. Integration of novel targeted therapies is challenging because of barriers in testing and drug access. We, therefore, sought to characterize the treatm
Externí odkaz:
https://doaj.org/article/1c185004b807431a8e7cb5c371cc5890
Autor:
Tracy L. Stockley, Bryan Lo, Adrian Box, Andrea Gomez Corredor, John DeCoteau, Patrice Desmeules, Harriet Feilotter, Daria Grafodatskaya, Cynthia Hawkins, Weei Yuarn Huang, Iyare Izevbaye, Guylaine Lepine, Andreas I. Papadakis, Paul C. Park, Brandon S. Sheffield, Danh Tran-Thanh, Stephen Yip, Ming Sound Tsao
Publikováno v:
Current Oncology, Vol 30, Iss 4, Pp 3989-3997 (2023)
The detection of gene fusions by RNA-based next-generation sequencing (NGS) is an emerging method in clinical genetic laboratories for oncology biomarker testing to direct targeted therapy selections. A recent Canadian study (CANTRK study) comparing
Externí odkaz:
https://doaj.org/article/24b1f17f55c2433ebe284fadc6a7249a
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 5688-5702 (2023)
Abstract Background Lung squamous cell carcinoma (LUSC) currently has limited therapeutic options because of the relatively few validated targets and the lack of clinical drugs for some of these targets. Although NRF2/NFE2L2 pathway activation common
Externí odkaz:
https://doaj.org/article/43677a905b7b403981e1fc2c470aac97
Publikováno v:
The European respiratory journal [Eur Respir J] 2016 Sep; Vol. 48 (3), pp. 962.
Autor:
Kamdin Mirsanaye, Leonardo Uribe Castaño, Yasmeen Kamaliddin, Ahmad Golaraei, Lukas Kontenis, Edvardas Ẑurauskas, Roya Navab, Kazuhiro Yasufuku, Ming-Sound Tsao, Brian C. Wilson, Virginijus Barzda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The extracellular matrix (ECM) is amongst many tissue components affected by cancer, however, morphological changes of the ECM are not well-understood and thus, often omitted from diagnostic considerations. Polarimetric second-harmonic gener
Externí odkaz:
https://doaj.org/article/658ac9a3764a4af08435107b2ccd7fee
Autor:
Shideh Mirhadi, Shirley Tam, Quan Li, Nadeem Moghal, Nhu-An Pham, Jiefei Tong, Brian J. Golbourn, Jonathan R. Krieger, Paul Taylor, Ming Li, Jessica Weiss, Sebastiao N. Martins-Filho, Vibha Raghavan, Yasin Mamatjan, Aafaque A. Khan, Michael Cabanero, Shingo Sakashita, Kugeng Huo, Sameer Agnihotri, Kota Ishizawa, Thomas K. Waddell, Gelareh Zadeh, Kazuhiro Yasufuku, Geoffrey Liu, Frances A. Shepherd, Michael F. Moran, Ming-Sound Tsao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
With non-small cell lung cancer (NSCLC) being the leading cause of cancer deaths worldwide, the development of targeted therapies remains crucial. Here, the generation and multi-omics characterization of 137 NSCLC patient-derived xenografts provides
Externí odkaz:
https://doaj.org/article/ca6f25a2b4ee419cb65ec4d91e659e4f
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Kirsten rat sarcoma viral oncogene homolog mutations are observed in 25% of lung adenocarcinoma and 40% of these are G12C mutations. Historically, no approved targeted agents were available for patients with any KRAS mutation, and response rates to s
Externí odkaz:
https://doaj.org/article/a72cd08431844f868d2e8b1e1cddf4db