Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Ming‐Sing Si"'
Autor:
Hüseyin Sicim, Pierre Emmanuel Noly, Suyash Naik, Vikram Sood, Richard G. Ohye, Jonathan W. Haft, Keith D. Aaronson, Francis D. Pagani, Ming-Sing Si, Paul C. Tang
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background Adult patients surviving with congenital heart disease (ACHD) is growing. We examine the factors associated with heart transplant outcomes in this challenging population with complex anatomy requiring redo-surgeries. Methods We re
Externí odkaz:
https://doaj.org/article/f157ad6dcaea4c91b6ab733b588aca39
Autor:
Gloria K. E. Zodanu, John H. Hwang, Zubin Mehta, Carlos Sisniega, Alexander Barsegian, Xuedong Kang, Reshma Biniwale, Ming-Sing Si, Gary M. Satou, Nancy Halnon, UCLA Congenital Heart Defect BioCore Faculty, Wayne W. Grody, Glen S. Van Arsdell, Stanley F. Nelson, Marlin Touma
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5469 (2024)
Fibrillin-1 and fibrillin-2, encoded by FBN1 and FBN2, respectively, play significant roles in elastic fiber assembly, with pathogenic variants causing a diverse group of connective tissue disorders such as Marfan syndrome (MFS) and congenital contra
Externí odkaz:
https://doaj.org/article/9d710e9660e847b7a5914b462c7b9909
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Ventricular assist devices have become a valuable tool in the treatment of heart failure in children. The use of ventricular assist devices has decreased mortality in children with end-stage heart failure awaiting transplant. It is not uncommon for c
Externí odkaz:
https://doaj.org/article/1e498abb366b424ba2c4519266760e0c
Autor:
Reiri Sono, Tania M. Larrinaga, Alden Huang, Frank Makhlouf, Xuedong Kang, Jonathan Su, Ryan Lau, Valerie A. Arboleda, Reshma Biniwale, Gregory A. Fishbein, Negar Khanlou, Ming-Sing Si, Gary M. Satou, Nancy Halnon, UCLA Congenital Heart Defects-BioCore Faculty, Glen S. Van Arsdell, Carol C. Gregorio, Stanly Nelson, Marlin Touma
Publikováno v:
Cells, Vol 12, Iss 11, p 1455 (2023)
As an essential component of the sarcomere, actin thin filament stems from the Z-disk extend toward the middle of the sarcomere and overlaps with myosin thick filaments. Elongation of the cardiac thin filament is essential for normal sarcomere matura
Externí odkaz:
https://doaj.org/article/1549951580934b4d81d7ef112d28c224
Autor:
Shuyun Wang, Shan Huang, Sean Johnson, Vadim Rosin, Jeffrey Lee, Eric Colomb, Russell Witt, Alexander Jaworski, Stephen J. Weiss, Ming‐Sing Si
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 9, Pp 1102-1113 (2020)
Abstract Although mesenchymal stem/stromal cells (MSCs) are being explored in numerous clinical trials as proangiogenic and proregenerative agents, the influence of tissue origin on the therapeutic qualities of these cells is poorly understood. Compl
Externí odkaz:
https://doaj.org/article/e44b75a6ee454a73bb58ae41b8a392ff
Autor:
Aisha Khan, Michael A. Bellio, Ivonne H. Schulman, Allan D. Levi, Bangon Longsomboon, Adriana Brooks, Krystalenia Valasaki, Darcy L. DiFede, Marietsy V. Pujol, Dileep R. Yavagal, Karen E. Bates, Ming-Sing Si, Sunjay Kaushal, Barth A. Green, Kimberly D. Anderson, James D. Guest, Stephen Shelby Burks, Risset Silvera, Andrea J. Santamaria, Anil Lalwani, W. Dalton Dietrich, Joshua M. Hare
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The U.S. Food and Drug Administration (FDA) provides guidance for expanded access to experimental therapies, which in turn plays an important role in the Twenty-first Century Cures Act mandate to advance cell-based therapy. In cases of incurable dise
Externí odkaz:
https://doaj.org/article/5fdee15486a94639ba28f46791a8f3d0
Autor:
Reilly D. Hobbs, MD, Ming-Sing Si, MD
Publikováno v:
JTCVS Open, Vol 1, Iss , Pp 49-50 (2020)
Externí odkaz:
https://doaj.org/article/d8e54997c2e345ad8f900d4fb388e064
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Newborns with critical congenital heart disease are at significant risk of developing heart failure later in life. Because treatment options for end-stage heart disease in children are limited, regenerative therapies for these patients would be of si
Externí odkaz:
https://doaj.org/article/79aec9c391224edaa2026895374f7f66
Autor:
Josue Chery, Shan Huang, Lianghui Gong, Shuyun Wang, Zhize Yuan, Joshua Wong, Jeffrey Lee, Sean Johnson, Ming-Sing Si
Publikováno v:
Bioengineering, Vol 6, Iss 1, p 15 (2019)
Right ventricle (RV) failure secondary to pressure overload is associated with a loss of myocardial capillary density and an increase in oxidative stress. We have previously found that human neonatal thymus mesenchymal stem cells (ntMSCs) promote neo
Externí odkaz:
https://doaj.org/article/e37a7de01e4e4ae68a47d9f06bc9902b
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Autologous and nonautologous bone marrow mesenchymal stem/stromal cells (MSCs) are being evaluated as proangiogenic agents for ischemic and vascular disease in adults but not in children. A significant number of newborns and infants with critical con
Externí odkaz:
https://doaj.org/article/129a7b86cdaa4b2fb53769e8bbf4e75c