Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Ming, H. Zheng"'
Autor:
Ziming Chen, Mengyuan Li, Peilin Chen, Andrew Tai, Jiayue Li, Euphemie Landao Bassonga, Junjie Gao, Delin Liu, David Wood, Brendan F. Kennedy, Qiujian Zheng, Ming H. Zheng
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 3, Pp 583-599 (2024)
Abstract Tendinopathy is one of the most common musculoskeletal diseases, and mechanical overload is considered its primary cause. However, the underlying mechanism through which mechanical overload induces tendinopathy has not been determined. In th
Externí odkaz:
https://doaj.org/article/e9bc9f1e1ecd44829ff9f4aa6ed28725
Autor:
Tao Wang, Peilin Chen, Lianzhi Chen, Yinghong Zhou, Allan Wang, Qiujian Zheng, Christopher A. Mitchell, Toby Leys, Rocky S. Tuan, Ming H. Zheng
Publikováno v:
Journal of Orthopaedic Translation, Vol 29, Iss , Pp 42-50 (2021)
Background: Tendons are the force transferring tissue that enable joint movement. Excessive mechanical loading is commonly considered as a primary factor causing tendinopathy, however, an increasing body of evidence supports the hypothesis that overl
Externí odkaz:
https://doaj.org/article/e45822d556364d23bb3a3145b3434c8d
Autor:
Claudio Pizzolato, David G. Lloyd, Rod S. Barrett, Jill L. Cook, Ming H. Zheng, Thor F. Besier, David J. Saxby
Publikováno v:
Frontiers in Computational Neuroscience, Vol 11 (2017)
Musculoskeletal tissues respond to optimal mechanical signals (e.g., strains) through anabolic adaptations, while mechanical signals above and below optimal levels cause tissue catabolism. If an individual's physical behavior could be altered to gene
Externí odkaz:
https://doaj.org/article/dae5562aebca4d80b246f05e878c1561
Autor:
Rocky S. Tuan, Ming H. Zheng, Peilin Chen, Yinghong Zhou, Toby Leys, Tao Wang, Christopher A. Mitchell, Allan Wang, Qiujian Zheng, Lianzhi Chen
Publikováno v:
Journal of Orthopaedic Translation
Journal of Orthopaedic Translation, Vol 29, Iss, Pp 42-50 (2021)
Journal of Orthopaedic Translation, Vol 29, Iss, Pp 42-50 (2021)
Background Tendons are the force transferring tissue that enable joint movement. Excessive mechanical loading is commonly considered as a primary factor causing tendinopathy, however, an increasing body of evidence supports the hypothesis that overlo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946db9558fdc87e0d1330acf3aae22cc
http://europepmc.org/articles/PMC8142054
http://europepmc.org/articles/PMC8142054
Pretreatment of Cisplatin in Recipients Attenuates Post-Transplantation Pancreatitis in Murine Model
Publikováno v:
International Journal of Biological Sciences, Vol 8, Iss 3, Pp 298-309 (2012)
Pancreas transplantation is the definite treatment for type 1 diabetes that enables the achievement of long-term normoglycemia and insulin independence. However Post-Transplantation Pancreatitis (PTP) due to ischemia reperfusion (IR) injury and prese
Externí odkaz:
https://doaj.org/article/6c5c29631f3844cf9071518357f60c5f
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125696 (2015)
Disulfiram (DSF), a cysteine modifying compound, has long been clinically employed for the treatment of alcohol addiction. Mechanistically, DSF acts as a modulator of MAPK and NF-κB pathways signaling pathways. While these pathways are crucial for o
Externí odkaz:
https://doaj.org/article/0020eaf6b8df4e2c835b95b423e3c710
Autor:
Rocky S. Tuan, Claudia Wittner, Sasha Senck, Renate Gehwolf, Qing Jiang, Huajian Teng, Toby Leys, Andreas Traweger, Allan Wang, Qiujian Zheng, Wenjin Yan, Ming H. Zheng, Christine B.F. Thien, Christine Lehner, Tao Wang, Herbert Tempfer, Nadja Weissenbacher, Andrea Wagner, Fabian S. Passini, Ming Ni, Jess G. Snedeker, Zhen Lin, John M. Papadimitriou, Jin Dai
Publikováno v:
Science Translational Medicine. 13
Tendons and tendon interfaces have a very limited regenerative capacity, rendering their injuries clinically challenging to resolve. Tendons sense muscle-mediated load; however, our knowledge on how loading affects tendon structure and functional ada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acf77d6e96c31cc5da3cc9a6ac6c334
https://doi.org/10.1126/scitranslmed.abe5738
https://doi.org/10.1126/scitranslmed.abe5738
Autor:
Ee Cheng Khor, Tamara Abel, Jennifer Tickner, Shek Man Chim, Cathy Wang, Taksum Cheng, Benjamin Ng, Pei Ying Ng, Dian Astari Teguh, Jacob Kenny, Xiaohong Yang, Honghui Chen, Keiichi I Nakayama, Keiko Nakayama, Nathan Pavlos, Ming H Zheng, Jiake Xu
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70815 (2013)
Bone remodeling is intrinsically regulated by cell signaling molecules. The Protein Kinase C (PKC) family of serine/threonine kinases is involved in multiple signaling pathways including cell proliferation, differentiation, apoptosis and osteoclast b
Externí odkaz:
https://doaj.org/article/b07293b3ee194bec97ada0b730e1bdba
Publikováno v:
Journal of Shoulder and Elbow Surgery. 27:e300-e307
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618cf997847b5312654c6d2889d419f4
https://doi.org/10.1016/j.jse.2018.06.013
https://doi.org/10.1016/j.jse.2018.06.013
Autor:
Rocky S. Tuan, Ming H. Zheng, Carolyn Wang, Qiujian Zheng, Allan Wang, Tao Wang, Junjie Gao, Qing Jiang, Christine B.F. Thien, Ming Ni
Publikováno v:
The FASEB Journal. 32:4804-4814
The tendon is a mechanosensitive tissue, but little is known about how mechanical stimulation selectively signals tenogenic differentiation and neo-tendon formation. In this study, we compared the impact of uniaxial and biaxial mechanical loading on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c59be98a5b10ea9e0ca69b8cc9d530
https://doi.org/10.1096/fj.201701384r
https://doi.org/10.1096/fj.201701384r